Rabbit IgG, polyclonal - Isotype Control from Abcam

Product Specs
ItemRabbit IgG, polyclonal - Isotype Control
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab37415
Quantity1 mg, 5 mg
ApplicationsChIP/Chip, ELISA, Flow Cyt, ICC/IF, IHC-P
Concentration5 mg/ml
IsotypeIgG
HostRabbit
Conjugate/Tag/LabelUnconjugated
Validated ApplicationsELISA, FCM, IHC-p, ChIP, ICC, IF
ClonalityPolyclonal
Antibody TypeIsotype Control Antibody

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(1) Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinomaOncol RepApril 14, 2026Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin0.5% BSA and conjugated with 5 µg anti-H3K27ac (cat. no. ab4729) or control IgG antibody (cat. no. ab37415) (both Abcam) for ≥4 h at 4°C on a rotating platform. The antibody-conjugated beads were washed three

(2) Histone methyltransferase G9a crosstalks with H3K36 histone methyltransferases NSD3 and SETD2 to mediate gene activationFrontiers in Cell and Developmental BiologyMarch 26, 2026Arunim Shah, Chandra Prakash Chaturvedi, Kulwant Singh, Shobhita Katiyar, Akhilesh Sharma(SC-515695), anti-IgG mouse Isotype control (SC-2025). From Abcam, we used anti-IgG rabbit isotype control (ab37415). Anti-SETD2 (same as WB). For ChIP, we used the following antibodies Anti-NSD3 (same as IP); Anti-G9a

(3) Matrine improves bile acid metabolism and reduces inflammatory and oxidative stress in colitis via the JAK2 pathwayChin MedMarch 26, 2026Zhi-Xian Jiang, Xue-Liang Chen, Qi Sun, Li-Chao Yang, Ya-Wei Zhang, Qiang Wu, Heng-Chang Yao, Dan Zhang, Lian-Wen Yuanusing primary antibodies against JAK2 (bs-0908R, Bioss, Woburn, USA) or a rabbit IgG (isotype control, ab37415, Abcam, Cambridge, UK). The slices were washed in PBS, then incubated for 30 min at 37 °C with the poly-IgG-HRP

(4) Targeting Inhibin Enhances Wagyu Oocyte Competence and Embryo Quality: A Comparative Study of In Vivo Immunization and In Vitro Antibody SupplementationAntioxidants (Basel)March 26, 2026Jingyu Ren, Fuhan Liu, Gang Liu, Biao Wang, Jie Zhu, Yongbin Liu, Yanfeng DaiCambridge, UK) to verify antibody specificity. (4) IgG Group: Supplemented with non-specific IgG isotype (ab37415, Abcam, Cambridge, UK; 1 μg/mL). 2.9. In Vitro Maturation (IVM) COCs were washed and cultured in maturation

(5) Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeresCell ReportsMarch 24, 2026Erin R. Taylor, Bruce Proctor, Melina Vaurs, Guanhui Wu, Manon Mahieu, Shreya Shrestha, Daniel Morrison, Laila Weatherly, Shane Brelinsky, Maya Raghunandan, et al.used H3 (Abcam, #AB1791, 3μg), H3K9me3 (Abcam, #AB8898, 5μg), HP1α (Abcam, #AB77256, 10 μg), IgG (Abcam, #AB37415, 5μg). Cell growth assay Cells were seeded in a 24-well tissue culture plate and treated according

(6) Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasisCell Death & DiseaseMarch 20, 2026Yunzhen Qian, Zhixiu Yan, Junjie Wang, Qi An, Jiamei Luo, Musitaba Mutailifu, Aziguli Tulamaiti, Xue-Li Zhang, Zhi-Gang Zhang, Dong-Xue LiProteintech), and recombinant antibody against Ki-67 (GB1514499, Servicebio, China). The isotype control was ab37415 (polyclonal rabbit IgG, Abcam). Subsequently, a secondary HRP-conjugated antibody (M21002S, Abmart,

(7) Endothelial cells temporally orchestrate lymphocyte dynamics and functional outcomes after ischemic strokeFluids and Barriers of the CNSMarch 14, 2026Yongzhi Zhou, Feng Yang, Yimin Lu, Guangmao Yu, Jianli Wang, Huaming LiBioXcell, BE0020-1; at day 0, 1), or an equivalent dose of an isotype-matched control antibody (Abcam, ab37415) [32]. Brain tissue processing and sectioning Mice were euthanized and perfused transcardially with

(8) Neutrophil extracellular traps drive peritoneal inflammation and tissue remodeling in pediatric peritoneal dialysisPediatric NephrologyMarch 1, 2026Charlotte Maria Dücker, Martin Herrmann, Susanne Boettcher, Sarah Bauer-Carmona, Raphael-Sebastian Schild, Lavinia Schönfeld, Laia Pagerols Raluy, Konrad Reinshagen, Claus Peter Schmitt, Maria Bartosova Medvid, et al.following antibodies were used for DNase1: bs-7651R, 1: 100, Rabbit, Bioss Antibodies; Iso DNase1: ab37415, 1:500, Rabbit, Abcam and for DNase1L3: bs-7653R, 1:100, Rabbit, Bioss Antibodies; Iso DNase1L3: ab37415,

(9) microRNA-210 in red blood cells differentially regulates vascular endothelial function between type 1 and type 2 diabetesPhysiol RepFebruary 23, 2026Tong Jiao, John Tengbom, Eftychia Kontidou, Álvaro Santana-Garrido, Rawan Humoud, Michael Alvarsson, Kesavan Manickam, Jiangning Yang, Ali Mahdi, Aida Collado, et al.isotype controls (Abcam). Isotype controls were used as negative controls (rabbit IgG, catalog no. ab37415 or mouse IgG2b, catalog no. ab18469, both from Abcam). Images were captured with a microscope (Leica

(10) PKC-eta promotes breast cancer metastasis by regulating the Hippo–YAP signaling pathwaySignal Transduction and Targeted TherapyFebruary 17, 2026Vijayasteltar B. Liju, Kamran Waidha, Amitha Muraleedharan, Divya Ram Jayaram, Hodaya Haimov, Sankar Jagadeeshan, Dinesh Babu Manikandan, Raghda Abu Shareb, Livingstone Nurukurti, Menachem Sklarz, et al.mentioned above) and immunoblotted with an anti-YAP antibody. An anti-rabbit IgG isotype control (#ab37415; Abcam, Cambridge, UK) was used. Co-IP of 14-3-3 with a mouse monoclonal antibody against YAP1 Following

(11) Dental pulp stem cells and hydroxyapatite: a promising combination for maxillary bone regenerationBMC Oral HealthFebruary 12, 2026Nur Atmaliya Luchman, Rohaya Megat Abdul Wahab, Shahrul Hisham Zainal Ariffin, Farinawati Yazid, Nurrul Shaqinah Nasruddin, Seng Fong LauUK). Isotype-matched control antibodies, including mouse IgG1 (ab170190, Abcam, UK) and rabbit IgG (ab37415, Abcam, UK), were included at the same concentration as the primary antibodies to confirm staining specificity

(12) Developmental convergence and divergence in human stem cell models of autismNatureJanuary 29, 2026Aaron Gordon, Se-Jin Yoon, Lucy K. Bicks, Jacqueline M. Martín, Greta Pintacuda, Stephanie Arteaga, Brie Wamsley, Qiuyu Guo, Lubayna Elahi, Ricardo E. Dolmetsch, et al.were used: rabbit IgG monoclonal (EPR25A) (Abcam, no. ab172730), rabbit IgG polyclonal (Abcam, no. ab37415) and mouse IgG1 κ monoclonal [MOPC-21] (Abcam, no. ab18443). Mass spectrometry experiments that yielded

(13) Hypoxic-immune axis orchestrates metastatic dissemination via HIF isoform imbalance in pancreatic neuroendocrine tumorsiScienceJanuary 16, 2026Jianli Lin, Yi Lin, Min Cai, Yaoqi Chen, Xiafang Lin, Lizhi Li, Jianlin Lai, Huping Huang, Jinxin Li, Qinwen Liu, et al.AB_3261223 HIF-1α,Raybiotech,119–10671 HIF-1β,Raybiotech,119–10645 HIF-2α,Raybiotech,119–10639 GAPDH,NOVUS,Cat# nb02374; RRID: AB_2107445 IgG,Abcam,Cat# ab37415; RRID: AB_2631996 FITC Anti-Human CD3 Antibody [OKT-3],Elabscience,E-AB-F1001C APC Anti-Human CD8a Antibody [OKT-8

(14) Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8bioRxivJanuary 8, 2026Hyunkyung Kong, Jiyeon Choi, Tongwu Zhang, Cathrin Gräwe, Mai Xu, Rohit Thakur, Hayley Sowards, Rebecca C Hennessey, Andrew Vu, Jianxin Shi, et al.cells were used for each immunoprecipitation reaction with anti-E4F1, anti-IRF2 or anti-IgG (Abcam, ab37415) following the instructions. Purified immunoprecipitated DNA or input DNA was analyzed by SYBR Green

(15) IL-33 blockade attenuates vascular inflammation in a mouse model of Kawasaki disease vasculitisClinical and Experimental ImmunologyJanuary 6, 2026Thacyana T. Carvalho, Benjamin L. Ross, Prasant K. Jena, Asli E. Atici, Angela C. Gomez, Michael C. Fishbein, Emily A. Aubuchon, Youngho Lee, Richard T. Lee, Elizabeth A. Jacobsen, et al.control IgG from goat serum (Sigma-Aldrich, I5256) and Rabbit IgG, polyclonal (Isotype Control; Abcam, ab37415) were used as negative controls for IL-33 and ST2, respectively. On the next day, samples were washed

(16) PROCA11 early activation fuels prostate cancer neuroendocrine traits by regulating cell survival and migrationiScienceDecember 19, 2025Rocco Cipolla, Marc Gabriel, Ugo Szachnowski, Zhimin Wang, Martina Romani, Giorgia Ianese Regin, Micaela Piemontese, Virginie Firlej, Marina Pinskaya, Antonin Morillonpre-cleared as described in Feng et al.81 Precleared lysates (2 mg) were incubated overnight with IgG (Ab37415, Abcam) or CCAR2 (ab215852, Abcam) or CTNNA1 (ab51032, Abcam) antibody (Table S14) on a wheel at 4°C

(17) VNUT-mediated ATP release suppresses T helper 1 (T H 1) cell differentiation via the P2X7R-JNK-FOXO3a-Eomes signaling cascadeScience AdvancesDecember 19, 2025Bolong Wu, Linlin Sheng, Ziyi Feng, Xiaohu Wang, Ligong ChenSignaling Technology (CST)]. Brief, with anti-FoxO3 antibody (128290, CST) or rabbit immunoglobulin G (ab37415, Abcam). Primers for FoxO3a ChIP-qPCR were synthesized and are listed in table S2. Statistics All

(18) Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic CardiomyopathyJournal of Cardiovascular Development and DiseaseNovember 19, 2025Jamie R. Johnston, Isabella Leite Coscarella, Carson L. Rose, Yun Shi, Hosna Rastegarpouyani, Karissa M. Dieseldorff Jones, Jennifer M. Le Patourel, Feyikemi Ogunfuwa, Adriano S. Martins, Kathryn M. Crotty, et al.rabbit anti-PCM-1 (Sigma, St. Louis, MO, USA, HPA023374) or isotype rabbit IgG (Abcam, Waltham, MA, USA, ab37415), both used at 8 µg/mL final concentration in NSB (0.44 mol/L sucrose, 10 mmol/L Tris-HCl pH 7.2, 70

(19) Ben_0691 functions as an IRG-47 mycoplasma stimulator that mediates host cell resistance to Mycoplasma mycoides subsp. mycoides infectionCommunications BiologyNovember 14, 2025Tong Liu, Huanjun Zhao, Xiumei Wang, Qingyuan Xu, Yuan Li, Qi Wu, Yukun Wei, Jiuqing Xin, Qiao Panwith the rabbit anti-ATP5A1 polyclonal antibody or rabbit IgG isotype control polyclonal antibody (ab37415; Abcam) for 1 h at 37 °C. Subsequently, the cells were incubated with goat anti-rabbit IgG-Alexa Fluor

(20) Identifying TP53RK as a key regulator of colorectal cancer survival and a potential therapeutic targetSci RepOctober 16, 2025Younghee Choi, Seowoo Park, Seojin Yang, Eunju Kim, Youngwon Cho, Hye-Ju Yang, Eugene C. Yi, Sang-Hyun Song, Tae-You Kimwhole-cell extract and rotated at 4 °C for 4 h. The following antibodies were used: rabbit IgG (Abcam; ab37415); rabbit anti-HA tag (Abcam; ab9110); mouse IgG (Abcam; ab37355); mouse anti-HA tag (Abcam; ab18181);

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Rabbit IgG, polyclonal - Isotype Control from Abcam

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Rabbit IgG, polyclonal - Isotype Control from Abcam

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