Custom Select siRNA from Thermo Fisher Scientific

Product Specs
ItemCustom Select siRNA
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number4390827
Quantity5nmol
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
TypesiRNA

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) A Phosphorylation Switch Governs KIF11’s Mechanical Output During MitosisbioRxivJanuary 29, 2026Amila Šemić, Babu J N Reddy, Joseph M Muretta, Sarah E Vandal, Alex F Thompson, Cindy L Fonseca, Steven S Rosenfeld, Steven P Gross, Jason StumpffAM4613)) or KIF11 siRNA (antisense sequence: AUUGUCUUCAGGUCUUCAGtt; (ThermoFisher Silencer Select, 4390827)) for 24 hr before fixing or imaging. Generation & validation of RPE1 inducible cell lines HILO-RMCE

(2) Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiationCancer CellMay 12, 2025Mona Teng, Jiacheng Guo, Xin Xu, Xinpei Ci, Yulin Mo, Yakup Kohen, Zuyao Ni, Sujun Chen, Wang Yuan Guo, Martin Bakht, et al.backspliced junction of circRMST were ordered from ThermoFisher (Silencer select custom design siRNA, cat. #4390827). siRNA sequences can be found in Table S6. Silencer select negative control no.1 siRNA (ThermoFisher,

(3) Integrated mathematical and experimental modeling uncovers enhanced EMT plasticity upon loss of the DLC1 tumor suppressorPLoS Comput BiolMay 12, 2025Sebastian Höpfl, Merih Özverin, Helena Nowack, Raluca Tamas, Andrew G. Clark, Nicole Radde, Monilola A. Olayioyenon-targeting control pool D-001810–10 (Dharmacon), siDLC1#1 (Silencer Select Custom siDLC1#97, Cat No. 4390827, Ambion by life technologies) and siDLC1#2 (Hs_DLC1 siRNA_11, Cat No. 1027417, Qiagen). TGFβ stimulation For

(4) Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteriesEuropean Journal of Cell BiologyMarch 1, 2025Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Abigail J. Clevenger, Zarek Burton, Megan E. Goeckel, et al.siPORTAmine (ThermoFisher Scientific, Cat.#: AM4503) and 50 nM of siRNA to Piezo1 (Life Technologies, Cat. #: 4390827) versus a negative control 2 siRNA (Life Technologies, Cat. #: 4390847). Following 3 days of incubation

(5) Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stabilityThe Journal of biological chemistryNovember 1, 2021Graziano S, Coll-Bonfill N, Teodoro-Castro B, Kuppa S, Jackson J, Shashkova E, Mahajan U, Vindigni A, Antony E, Gonzalo S.h), SMARCAL1 (D-013058-02-0002; 50 nM, 48 h), whereas RAD51 was depleted by employing siRNA Ambion (4390827; 50 nM, 48 h) as described (28). In each experiment, silencer select negative siRNA (4390843; Ambion)

(6) Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowingNucleic acids researchFebruary 20, 2019Carvajal-Maldonado D, Byrum AK, Jackson J, Wessel S, Lemaçon D, Guitton-Sert L, Quinet A, Tirman S, Graziano S, Masson JY, et al.Rad50 (Dharmacon sequence: 5′-CTGCGACTTGCTCCAGATAAA-3′, 50 nM for 48 h) (43), Rad51 (Ambion, Cat. No. 4390827, sequence- 5′-GUGCUGCAGCCUAAUGATT-3′, 50 nM, 48 h) (40), Smarcal1 (Dharmacon, Cat. No. D-013058-04-002,

(7) Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampusMolecular and Cellular NeuroscienceOctober 1, 2018Jacqueline E. McDermott, Dena Goldblatt, Suzanne ParadisPlexin-B2 shRNAs were chosen from previously derived siRNA sequences [Life technologies; PlexinB1 (4390827) and PlexinB2 (4390771)], and were cloned into the pSuper shRNA expression vector as previously described

(8) Reticulon 3 regulates very low density lipoprotein secretion by controlling very low density lipoprotein transport vesicle biogenesisCanadian Journal of Physiology and PharmacologyJuly 1, 2018Shaila Siddiqi, Olga Zhelyabovska, Shadab A. Siddiqi5’CAAUGGUGCAUGUCAACAAtt3’, (Silencer select Custom-designed siRNA, Life Technologies, Grand Island, NY; #4390827) using Lipofectamine RNAiMax following the manufacturer’s instructions (Life Technologies, Grand Island,

(9) Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cellsOncotargetFebruary 9, 2018Sumati Gupta, Kelly Doyle, Timothy L. Mosbruger, Andrew Butterfield, Alexis Weston, Allison Ast, Mohan Kaadige, Anupam Verma, Sunil SharmaRabbit mAb #2184S. Abcam Mouse mAb to n-Myc [NCM II 100] ab16898. siRNA LSD1 SiRNA: Ambion Cat#: 4390827. Negative control Silencer – Negative Control siRNA #1 – Ambion AM4611 – 50 uM concentration.

(10) Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stressThe Journal of clinical investigationJanuary 2, 2018Ersoy BA, Maner-Smith KM, Li Y, Alpertunga I, Cohen DE.5′-CUCCUUCUUCUGCUUCUCAcU-3′ sequences (Invitrogen, catalog 152 jci.org Volume 128 Number 1 January 2018 4390827). cDNAs encoding ACOT7 and ACOT12 (Open Biosystems) were cloned into a pcDNA3 plasmid (Invitrogen) using

(11) MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cellsNature CommunicationsDecember 1, 2017Delphine Lemaçon et al.nM, 48 h), as described33. The following genes were depleted with siRNA purchased from Ambion: DNA2 (4390827, 10 nM, 48 h), EXO1 (#1: 4392420 and #2: S17502, 40 nM, 48 h), RAD51 (4390827, 50 nM, 48 h) and MUS81

(12) BRAF V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cellsScientific ReportsMay 1, 2016Toshinori Sueda et al.and transfection The oligonucleotide small interfering RNA (siRNA) specifically targeting Atg13 (Custom Select, #:4390827) and negative control siRNA (Silence Select, #:4390843) were purchased from Life Technologies. Atg7

(13) The spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5AAmino acidsDecember 1, 2014Oliverio S, Corazzari M, Sestito C, Piredda L, Ippolito G, Piacentini M.Ambion: Oligos a-1 or b-1 were eIF5A Silencer Selected Predesigned siRNA # 4392420 or Custom Selected siRNA #4390827 for eIF5A-1; siRNA #4390824 for DHS and #12935-300 as a negative control (siCtrl). 5 × 105 cells/well

(14) Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor β1-Induced B-Cell ApoptosisJournal of VirologyMay 1, 2014Eva M. Campion, Roya Hakimjavadi, Sinéad T. Loughran, Susan Phelan, Sinéad M. Smith, Brendan N. D'Souza, Rosemary J. Tierney, Andrew I. Bell, Paul A. Cahill, Dermot Walls(4390824), Silencer negative control siRNA (AM4611), and anti-SMAD3 siRNA56 and anti-SMAD3 siRNA57 (4390827). The plasmids pSGEBNA2, pSGEBNA2WW323SR, pcDNA3-HA-BIK, and pcDNA3-HA-BIK⌬BH3 have been described elsewhere

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Custom Select siRNA from Thermo Fisher Scientific

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Custom Select siRNA from Thermo Fisher Scientific

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