Description
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272.
BTLA contains one Ig-like V-type (immunoglobulin-like) domain.
As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response.
BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.