SIRT1 siRNA (r) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSIRT1 siRNA (r)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-108043
Gene Namesirtuin 1
Quantity10 µM
Speciesrat
NCBI Full Gene Namesirtuin 1
NCBI Gene AliasesSIR2, SIR2L1, Sir2alpha, Sir2, SIR2alpha, Sir2a
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Acacetin Attenuates Lysophosphatidylcholine-Induced Vascular Smooth Muscle Cell Injury via Sirt1-Nrf2/p62 Signaling AxisBiomedicinesJanuary 15, 2026Yun-Da Li, Yao Wu, Tian-Li Zhou, Qian Yuan, Gui-Rong Li, Wei-Yin Wu, Yan Wang, Gang Lirespectively. Gene silencing experiments utilized validated siRNAs targeting Nrf2 (sc-156128), Sirt1 (sc-108043), and non-targeting control (sc-37007) from Santa Cruz Biotechnology. 2.2. Cell Cultures Primary vascular smooth muscle

(2) Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytesCellular signallingMay 1, 2023Rogacka D, Rachubik P, Audzeyenka I, Kulesza T, Szrejder M, Myślińska D, Angielski S, Piwkowska A.

(3) Ferulic Acid, Pterostilbene, and Tyrosol Protect the Heart from ER-Stress-Induced Injury by Activating SIRT1-Dependent Deacetylation of eIF2αInternational journal of molecular sciencesJune 14, 2022Monceaux K, Gressette M, Karoui A, Pires Da Silva J, Piquereau J, Ventura-Clapier R, Garnier A, Mericskay M, Lemaire C.cells to that of the corresponding protein in untreated cells. 4.9. siRNA Transfection SIRT1 siRNA (sc-108043) and non-targeting control siRNA were purchased from Santa Cruz (sc-37007). H9c2 cells were plated in

(4) Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 PathwayMolecules (Basel, Switzerland)April 6, 2022Song X, Du Z, Yao Z, Tang X, Zhang M.from Thermo Fisher Scientific (Waltham, MA, USA). siRNA transfection reagent (sc-29528), SirT1 siRNA (sc-108043), STAT3 siRNA (sc-270027), control siRNA (sc-37007) was purchased from Santa Cruz Biotechnology (Santa

(5) Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathwayEuropean journal of pharmacologyApril 5, 2022Cui YK, Hong YX, Wu WY, Han WM, Wu Y, Wu C, Li GR, Wang Y.

(6) Fibroblast growth factor 20 attenuates pathological cardiac hypertrophy by activating the SIRT1 signaling pathwayCell death & diseaseMarch 28, 2022Chen Y, An N, Zhou X, Mei L, Sui Y, Chen G, Chen H, He S, Jin C, Hu Z, et al.RNA interference, transient transfection of small interfering RNA targeting SIRT1 (si-SIRT1) (Santa Cruz, sc-108043) or a control scramble (si-Scr) (Santa Cruz, sc-37007) in NRCMs was performed using Lipofectamine RNAiMAX

(7) Mangiferin prevents myocardial infarction-induced apoptosis and heart failure in mice by activating the Sirt1/FoxO3a pathwayJournal of cellular and molecular medicineMarch 1, 2021Chen L, Li S, Zhu J, You A, Huang X, Yi X, Xue M.

(8) Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 SignalingOxidative medicine and cellular longevityJanuary 1, 2021Liu J, Jiao K, Zhou Q, Yang J, Yang K, Hu C, Zhou M, Li Z.

(9) Doxorubicin cardiomyopathy is ameliorated by acacetin via Sirt1-mediated activation of AMPK/Nrf2 signal moleculesJournal of cellular and molecular medicineOctober 1, 2020Wu WY, Cui YK, Hong YX, Li YD, Wu Y, Li G, Li GR, Wang Y.Institute (Nanjing, Jiangsu, China). Small interfering RNA (siRNA) molecules targeting rat Sirt1 mRNA (sc‐108043) was from Santa Cruz Biotechnology (Dallas, TX, USA), whereas siRNA molecules targeting rat AMPK and

(10) Effect of Aldosterone on Senescence and Proliferation Inhibition of Endothelial Progenitor Cells Induced by Sirtuin 1 (SIRT1) in Pulmonary Arterial HypertensionMedical science monitor : international medical journal of experimental and clinical researchApril 18, 2020Wang Y, Zhong B, Wu Q, Tong J, Zhu T, Zhang M.

(11) SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent AutophagyCellsFebruary 12, 2020Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A, Lemaire C.France). 2.5. siRNA Transfection SIRT1, eEF2K, eEF2 and eIF2α siRNAs were purchased from Santa Cruz (sc-108043, sc-39012, sc-43542 and sc-35273). H9c2 cells were plated overnight at 30 × 104 cells in 24-well plate

(12) Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathwayMolecular and cellular endocrinologyJanuary 15, 2020Ren H, Shao Y, Wu C, Ma X, Lv C, Wang Q.

(13) Prednisolone suppresses adriamycin-induced vascular smooth muscle cell senescence and inflammatory response via the SIRT1-AMPK signaling pathwayPloS oneJanuary 1, 2020Sung JY, Kim SG, Kim JR, Choi HC.

(14) VASH-1 Regulates Oxidative Stress and Fibrosis in Diabetic Kidney Disease via SIRT1/HIF1α and TGFβ1/Smad3 Signaling PathwaysFrontiers in molecular biosciencesJanuary 1, 2020Ren H, Shao Y, Wu C, Lv C, Zhou Y, Wang Q.

(15) PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascadesAgingNovember 16, 2019Liu D, Ma Z, Xu L, Zhang X, Qiao S, Yuan J.

(16) Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1Biochimica et biophysica acta. Molecular basis of diseaseJune 1, 2019Li S, Zhu Z, Xue M, Yi X, Liang J, Niu C, Chen G, Shen Y, Zhang H, Zheng J, et al.

(17) Total Salvianolic Acid Injection Prevents Ischemia/Reperfusion-Induced Myocardial Injury Via Antioxidant Mechanism Involving Mitochondrial Respiratory Chain Through the Upregulation of Sirtuin1 and Sirtuin3Shock (Augusta, Ga.)June 1, 2019Huang DD, Wei XH, Mu HN, Pan CS, Li Q, Hu BH, Chang X, Yan L, Fan JY, Liu YY, et al.

(18) Berberine Ameliorates Doxorubicin-Induced Cardiotoxicity via a SIRT1/p66Shc-Mediated PathwayOxidative medicine and cellular longevityJanuary 1, 2019Wu YZ, Zhang L, Wu ZX, Shan TT, Xiong C.

(19) SIRT1 facilitates amyloid beta peptide degradation by upregulating lysosome number in primary astrocytesNeural regeneration researchNovember 1, 2018Li MZ, Zheng LJ, Shen J, Li XY, Zhang Q, Bai X, Wang QS, Ji JG.RNA interference Primary astrocytes were transfected with a specific siRNA against the target gene (SIRT1 siRNA: Cat. No. sc-108043; Santa Cruz Biotechnology, Santa Cruz, CA, USA) or the scrambled siRNA (control) with Lipofectamine

(20) Berberine protects renal tubular cells against hypoxia/reoxygenation injury via the Sirt1/p53 pathwayJournal of natural medicinesJune 1, 2018Lin Y, Sheng M, Ding Y, Zhang N, Song Y, Du H, Lu N, Yu W.

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SIRT1 siRNA (r)

SIRT1 siRNA (r) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SIRT1 siRNA (r) from Santa Cruz Biotechnology, Inc.

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