Orai1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemOrai1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-76001
Gene NameORAI calcium release-activated calcium modulator 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameORAI calcium release-activated calcium modulator 1
NCBI Gene AliasesCRACM1, IMD9, ORAT1, TAM2, TMEM142A
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Store-operated Ca 2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cellsAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyJune 1, 2025Aleksandra Babicheva, Ibrahim Elmadbouh, Shanshan Song, Michael A. Thompson, Ryan Powers, Pritesh P. Jain, Amin Izadi, Jiyuan Chen, Lauren Yung, Sophia Parmisano, et al.Santa Cruz Biotechnology), STIM1 siRNA (Cat# sc-76589, Santa Cruz Biotechnology) or Orai1 siRNA (Cat# sc-76001, Santa Cruz Biotechnology) at the concentration of 60 pM for 6 h. Lipofectamine RNAiMAX (Invitrogen,

(2) Reduction of TRPC1/TRPC3 mediated Ca2+-signaling protects oxidative stress-induced COPDCellular SignallingJuly 1, 2023Samuel Shin, Farai C. Gombedza, Eugenia Awuah Awuah Boadi, Allen J. Yiu, Sanjit K. Roy, Bidhan C. Bandyopadhyay(Santa Cruz Biotechnology, Santa Cruz CA; sc-42666), ORAI1 (Santa Cruz Biotechnology, Santa Cruz CA; sc-76001), STIM1 (Santa Cruz Biotechnology, Santa Cruz CA; sc-76589) and nontarget (scrambled) siRNA-A (Santa Cruz Biotechnology

(3) Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C ExposureInternational journal of molecular sciencesMay 16, 2022Lewuillon C, Guillemette A, Titah S, Shaik FA, Jouy N, Labiad O, Farfariello V, Laguillaumie MO, Idziorek T, Barthélémy A, et al.

(4) TRPC1 participates in the HSV-1 infection process by facilitating viral entryScience advancesMarch 1, 2020He D, Mao A, Li Y, Tam S, Zheng Y, Yao X, Birnbaumer L, Ambudkar IS, Ma X.

(5) Expression of Concern: The Orai-1 and STIM-1 complex controls human dendritic cell maturationPloS oneJanuary 1, 2020PLOS ONE Editors.following product information for reagents used in this study: siRNA ORAI-1 (h), Santa Cruz Biotechnology #sc-76001; siRNA STIM-1 Santa Cruz Biotechnology #sc-76589; anti-ORAI1 antibody, Santa Cruz Biotechnology #A47359. Supporting

(6) Targeting Orai1-Mediated Store-Operated Ca(2+) Entry in Heart FailureFrontiers in cell and developmental biologyJanuary 1, 2020Luo R, Gomez AM, Benitah JP, Sabourin J.

(7) Bradykinin-mediated Ca(2+) signalling regulates cell growth and mobility in human cardiac c-Kit(+) progenitor cellsJournal of cellular and molecular medicineOctober 1, 2018Li G, Che H, Wu WY, Jie LJ, Xiao GS, Wang Y, Li GR.

(8) High salt induces P-glycoprotein mediated treatment resistance in breast cancer cells through store operated calcium influxOncotargetMay 18, 2018Babaer D, Amara S, Ivy M, Zhao Y, Lammers PE, Titze JM, Tiriveedhi V.

(9) Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemiaOncotargetJanuary 19, 2018Zheng S, Leclerc GM, Li B, Swords RT, Barredo JC.

(10) SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid OhmlineOncotargetJune 14, 2016Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, et al.equal volume of medium with serum was added to each well. The siRNA sequences directed against Orai1 (sc-76001), TRPC1 (sc-42664) and STIM1 (sc-76589) were purchased from Santa Cruz Biotechnologies. For Control

(11) Roles of store-operated Ca2+ channels in regulating cell cycling and migration of human cardiac c-kit+ progenitor cellsAmerican journal of physiology. Heart and circulatory physiologyNovember 15, 2015Che H, Li G, Sun HY, Xiao GS, Wang Y, Li GR.

(12) Mycobacterium tuberculosis and Human Immunodeficiency Virus Type 1 Cooperatively Modulate Macrophage Apoptosis via Toll Like Receptor 2 and Calcium HomeostasisPloS oneJanuary 1, 2015Mehto S, Antony C, Khan N, Arya R, Selvakumar A, Tiwari BK, Vashishta M, Singh Y, Jameel S, Natarajan K.

(13) A reciprocal shift in transient receptor potential channel 1 (TRPC1) and stromal interaction molecule 2 (STIM2) contributes to Ca2+ remodeling and cancer hallmarks in colorectal carcinoma cellsThe Journal of biological chemistryOctober 17, 2014Sobradillo D, Hernández-Morales M, Ubierna D, Moyer MP, Núñez L, Villalobos C.

(14) Antibody-mediated targeting of the Orai1 calcium channel inhibits T cell functionPloS oneJanuary 1, 2013Cox JH, Hussell S, Søndergaard H, Roepstorff K, Bui JV, Deer JR, Zhang J, Li ZG, Lamberth K, Kvist PH, et al.

(15) The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cellsMolecular pharmacologyApril 1, 2012Sundivakkam PC, Freichel M, Singh V, Yuan JP, Vogel SM, Flockerzi V, Malik AB, Tiruppathi C.

(16) Histamine regulates cyclooxygenase 2 gene activation through Orai1-mediated NFκB activation in lung cancer cellsCell calciumJuly 1, 2011Huang WC, Chai CY, Chen WC, Hou MF, Wang YS, Chiu YC, Lu SR, Chang WC, Juo SH, Wang JY, et al.

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Orai1 siRNA (h)

Orai1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Orai1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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