METTL3 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMETTL3 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-92172
Gene Namemethyltransferase like 3
Quantity10 µM
Specieshuman
NCBI Full Gene Namemethyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
NCBI Gene AliasesIME4, M6A, MT-A70, Spo8, hMETTL3
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Paramyxovirus matrix protein redirects METTL3 for dual regulation of viral replication and immune evasionPLoS PathogDecember 1, 2025Takashi Okura, Yusuke Nakai, Taichi Kameya, Fuminori Mizukoshi, Hiyori Okura, Masatoshi Kakizaki, Fumihiro Kato, Yusuke Matsumoto, Yuichiro Nakatsu, Kaoru Takeuchi, et al.established by transfection of the gene-specific shRNA expression plasmids for METTL3 (Santa Cruz, Cat. #sc-92172-S) and METTL14 (Santa Cruz, Cat. # sc-89054-SH), and then selected with 1.5 μg/ml puromycin (InvivoGen,

(2) Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule FormationMicroorganismsOctober 26, 2024Guangze Zhao, Huifang M. Zhang, Yankuan T. Chen, Kerry Shi, Sana Aghakeshmiri, Fione Yip, Honglin Luo, Bruce McManus, Decheng Yangwith CVB3 at an MOI of 50. 2.2. siRNA and Plasmid Transfections The siRNAs targeting human METTL3 (sc-92172), YTHDF2 (sc-78661) or ALKBH5 (sc-93856) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA).

(3) Adenosine Methylation Level of miR-125a-5p Promotes Anti-PD-1 Therapy Escape through the Regulation of IGSF11/VSIG3 ExpressionCancersJune 14, 2023Bougras-Cartron G, Nadaradjane A, Joalland MP, Lalier-Bretaudeau L, Raimbourg J, Cartron PF.and the 2−ΔΔCt formula. 2.8. siRNA Transfection siRNA directed against METTL3, KHDRBS3, and HuR (#sc-92172, #sc-40922, and sc-35619 Santa Cruz, Morzine, France) were used in this article. siRNA-A (#sc-37007,

(4) SLERT, as a novel biomarker, orchestrates endometrial cancer metastasis via regulation of BDNF/TRKB signalingWorld journal of surgical oncologyJanuary 31, 2023Tian J, Cheng H, Wang N, Wang C.

(5) Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiationJournal of translational medicineDecember 16, 2022Luo H, Liu W, Zhou Y, Zhang Y, Wu J, Wang R, Shao L.

(6) Regulation of AR mRNA translation in response to acute AR pathway inhibitionNucleic acids researchJanuary 25, 2022Somasekharan SP, Saxena N, Zhang F, Beraldi E, Huang JN, Gentle C, Fazli L, Thi M, Sorensen PH, Gleave M.(5′-UCAAGGAACUCGAUCGUAUUU-3′) targeting full-length AR was from Dharmacon; siESR1 (Cat. No. sc-29305), siMETTL3 (Cat. No. sc-92172), siWTAP (Cat. No. sc-63224), siKIAA1429 (Cat. No. sc-77700), siMETTL14 (Cat. No. sc-89054), and siControl

(7) MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancerBMC cancerNovember 13, 2021Pan H, Pan Z, Guo F, Meng F, Zu L, Fan Y, Li Y, Li M, Du X, Zhang X, et al.

(8) Multi-omic analysis of altered transcriptome and epigenetic signatures in the UV-induced DNA damage responseDNA repairOctober 1, 2021Liu J, Liu L, He J, Xu Y, Wang Y.

(9) The m⁶A landscape of polyadenylated nuclear (PAN) RNA and its related methylome in the context of KSHV replicationRNASeptember 1, 2021Sarah Elizabeth Martin, Huachen Gan, Gabriela Toomer, Nikitha Sridhar, Joanna Sztuba-Solinskatransfection. For transfection, 80 pmol target-specific siRNAs (Santa Cruz Biotechnology, siMETTL3 sc-92172, siFTO sc-75002, siRBM15 sc-76365, and control siRNA-A sc-37007) were combined with 1 ml OPTI-MEM (Thermo Fisher

(10) METTL3-mediated m(6)A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lungMolecular therapy. Nucleic acidsMarch 5, 2021Cheng C, Wu Y, Xiao T, Xue J, Sun J, Xia H, Ma H, Lu L, Li J, Shi A, et al.

(11) RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathwayAngiogenesisFebruary 1, 2021Qiao K, Liu Y, Xu Z, Zhang H, Zhang H, Zhang C, Chang Z, Lu X, Li Z, Luo C, et al.

(12) An N(6)-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cellsBiochemical pharmacologyFebruary 1, 2019Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY.Medical Center, and Tufts University School of Medicine, Boston, MA) [42]. siRNAs targeting human METTL3 (sc-92172) [29], Gb3 synthase (sc-72831) [36] and the scrambled control (siRNA-SC, sc-37007) were purchased from

(13) N(6)-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cellsToxicology lettersAugust 1, 2018Gu S, Sun D, Dai H, Zhang Z.

(14) Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N⁶-Adenosine Methylation To Promote Lytic ReplicationJournal of virologyAugust 15, 2017Ye F, Chen ER, Nilsen TW.

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METTL3 siRNA (h)

METTL3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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METTL3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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