Rictor siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRictor siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-61478
Gene NameRPTOR independent companion of MTOR, complex 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameRPTOR independent companion of MTOR complex 2
NCBI Gene AliasesAVO3, PIA, hAVO3
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Endothelial Mechanistic Target of Rapamycin Activation with Different Strains of R. rickettsii: Possible Role in Rickettsial PathogenesisMicroorganismsJanuary 30, 2024Abha Sahni, Jessica Alsing, Hema P. Narra, Michelle Montini, Yasim Zafar, Sanjeev K. SahniRaptor siRNA (25 or 50 nM, catalog #sc-44069), mTORC2-specific Rictor siRNA (25 or 50 nM, catalog #sc-61478), or control siRNA (50 nM, catalog #sc-44230) (Santa Cruz Biotechnology, Dallas, TX, USA) were transfected

(2) Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolismMolecular metabolismApril 1, 2023Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, et al.

(3) mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncouplingCommunications biologyJuly 22, 2022Wang Y, Li Q, Zhang Z, Peng K, Zhang DM, Yang Q, Passerini AG, Simon SI, Sun C.control siRNA (sc-37007), siRNA targeting KLF2 (sc-35818), RPTOR (encoding Raptor) (sc-44069), RICTOR (sc-61478), MTOR (sc-35409), RPS6KB1 (encoding p70S6K) (sc-36165) were purchased from Santa Cruz Biotechnology

(4) Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cellsPloS oneJanuary 1, 2022Hatipoglu A, Menon D, Levy T, Frias MA, Foster DA.described in the figure legends. siRNAs were used in the study: Rictor siRNA (Santa Cruz Biotechnology sc-61478), lysophosphatidic acid acyltransferase-β (LPAAT-β) siRNA (Dharmacon M003811) and non-targeting siRNA

(5) Amino acid deprivation induces AKT activation by inducing GCN2/ATF4/REDD1 axisCell death & diseaseDecember 3, 2021Jin HO, Hong SE, Kim JY, Jang SK, Park IC.kindly provided by Dr. Jawed Alam [30]. GCN2 (#sc-45644), ATF4 (#sc-35112), REDD1 (#sc-45806), Rictor (#sc-61478), Sin1 (#sc-60984) and control (#sc-37007) siRNAs were purchased from Santa Cruz Biotechnology (Dallas,

(6) TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2Oncology reportsFebruary 1, 2021Guo Z, Zhang X, Zhu H, Zhong N, Luo X, Zhang Y, Tu F, Zhong J, Wang X, He J, et al.transfected cells Knockdown of RICTOR expression was performed by transfecting cells with siRNA duplexes (sc-61478; Santa Cruz Biotechnology) using Lipofectamine 3000 (Thermo Fischer Scientific). Scrambled RNA (scr-siRNA)

(7) Different Role of Raptor and Rictor in Regulating Rasfonin-Induced Autophagy and Apoptosis in Renal Carcinoma CellsChemistry & biodiversityDecember 1, 2020Hou B, Liu S, Li E, Jiang X.

(8) TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activationNature communicationsAugust 11, 2020Kim HK, Bhattarai KR, Junjappa RP, Ahn JH, Pagire SH, Yoo HJ, Han J, Lee D, Kim KW, Kim HR, et al.

(9) Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cellsThe ProstateApril 1, 2020Venugopal SV, Caggia S, Gambrell-Sanders D, Khan SA.

(10) Induction of HSP27 and HSP70 by constitutive overexpression of Redd1 confers resistance of lung cancer cells to ionizing radiationOncology reportsMay 1, 2019Jin HO, Hong SE, Kim JY, Kim MR, Chang YH, Hong YJ, Lee JK, Park IC.samples. siRNAs and transfections. Redd1 (cat. no. sc‑45806), AKT1/2 (cat. no. sc‑43609), Rictor (cat. no. sc‑61478) and control (cat. no. sc‑37007) siRNAs were purchased from Santa Cruz Biotechnology, Inc. (Dallas,

(11) Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF-α-induced VCAM-1 expression and monocytic cell adhesionAmerican journal of physiology. Heart and circulatory physiologyFebruary 1, 2019Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C.

(12) Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and AktOncogenesisJanuary 23, 2018Katreddy RR, Bollu LR, Su F, Xian N, Srivastava S, Thomas R, Dai Y, Wu B, Xu Y, Rea MA, et al.and UT2 (c14orf37) (SiRNA ID: SASI_Hs01_00126164) were purchased from Sigma Aldrich. Rictor siRNA (sc-61478) was purchased from Santa Cruz Biotechnology. Rictor-myc expressing and control vectors were from Dr.

(13) The mTOR Kinase Inhibitor CZ415 Inhibits Human Papillary Thyroid Carcinoma Cell GrowthCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Li X, Li Z, Song Y, Liu W, Liu Z.

(14) mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human MonocytesFrontiers in immunologyJanuary 1, 2018Sohrabi Y, Lagache SMM, Schnack L, Godfrey R, Kahles F, Bruemmer D, Waltenberger J, Findeisen HM.concentrations of 60 nM small interfering RNA for Raptor (Santa Cruz, #sc-44069) and Rictor (Santa Cruz, #sc-61478) for 24 h using Viromer technology according to the manufacturer's protocol (Viromer Green, Lipocalyx).

(15) Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acidThe Journal of biological chemistryApril 14, 2017Menon D, Salloum D, Bernfeld E, Gorodetsky E, Akselrod A, Frias MA, Sudderth J, Chen PH, DeBerardinis R, Foster DA.

(16) Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signalingOncotargetJanuary 3, 2017Liu Y, Chen Z, Cheng H, Chen J, Qian J.

(17) microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma CellsPloS oneJanuary 1, 2016Cui Y, Zhao J, Yi L, Jiang Y.

(18) A carbazole alkaloid deactivates mTOR through the suppression of rictor and that induces apoptosis in lung cancer cellsMolecular and cellular biochemistryJuly 1, 2015Chatterjee P, Seal S, Mukherjee S, Kundu R, Bhuyan M, Barua NC, Baruah PK, Babu SP, Bhattacharya S.

(19) Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinomaOncotargetJanuary 30, 2015Chang CH, Chan PC, Li JR, Chen CJ, Shieh JJ, Fu YC, Chen HC, Wu MJ.

(20) mTORC2 controls cancer cell survival by modulating gluconeogenesisCell death discoveryJanuary 1, 2015Khan MW, Biswas D, Ghosh M, Mandloi S, Chakrabarti S, Chakrabarti P.

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Rictor siRNA (h)

Rictor siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Rictor siRNA (h) from Santa Cruz Biotechnology, Inc.

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