GPR30 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGPR30 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-60743
Gene NameG protein-coupled estrogen receptor 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameG protein-coupled estrogen receptor 1
NCBI Gene AliasesCEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR, mER
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) LNS8801: An Enantiomerically Pure Agonist of the G Protein-Coupled Estrogen Receptor Suitable for Clinical DevelopmentCancer Res CommunApril 1, 2025Natale CA, Mercado S, Zhuang R, Aguirre-Portolés C, Olayide I, Arnatt CK, Seykora JT, Garyantes TK, Luke W, Ridky TW.GPER gene from genomic DNA followed by Sanger Sequencing (Supplementary Fig. S2A–S2C). GPER siRNA, sc-60743, was purchased from Santa Cruz Biotechnology. HL-60 cells were centrifuged and plated in a six-well

(2) Suppression of G Protein-coupled Estrogen Receptor 1 (GPER1) Enhances the Anti-invasive Efficacy of Selective ERβ AgonistsAnticancer researchNovember 1, 2022Schmitz V, Bauerschmitz G, Gallwas J, Gründker C.

(3) Assessment of G Protein-Coupled Oestrogen Receptor Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal AntibodyInternational journal of molecular sciencesMay 6, 2022Bubb M, Beyer AL, Dasgupta P, Kaemmerer D, Sänger J, Evert K, Wirtz RM, Schulz S, Lupp A.A431 cells using chemically synthesised, double-stranded GPER small interfering RNA (siRNA) duplexes (sc-60743; Santa Cruz Biotechnology, Dallas, TX, USA) according to the manufacturer’s instructions. As a negative

(4) G-Protein-Coupled Estrogen Receptor 1 Promotes Gender Disparities in Hepatocellular Carcinoma via Modulation of SIN1 and mTOR Complex 2 ActivityMolecular cancer research : MCRDecember 1, 2020Feng G, Cai J, Huang Y, Zhu X, Gong B, Yang Z, Yan C, Hu Z, Yang L, Wang Z.

(5) β-estradiol adjusts intestinal function via ERβ and GPR30 mediated PI3K/AKT signaling activation to alleviate postmenopausal dyslipidemiaBiochemical pharmacologyOctober 1, 2020Meng Q, Li J, Chao Y, Bi Y, Zhang W, Zhang Y, Ji T, Fu Y, Chen Q, Zhang Q, et al.

(6) Bisphenol A induces focal adhesions assembly and activation of FAK, Src and ERK2 via GPER in MDA-MB-231 breast cancer cellsToxicology in vitro : an international journal published in association with BIBRAAugust 1, 2020Castillo-Sanchez R, Ramirez-Ricardo J, Martinez-Baeza E, Cortes-Reynosa P, Candanedo-Gonzales F, Gomez R, Salazar EP.

(7) Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cellsBMC pharmacology & toxicologyMay 1, 2020Shi D, Zhao P, Cui L, Li H, Sun L, Niu J, Chen M.

(8) Cisplatin resistance in gastric cancer cells is involved with GPR30-mediated epithelial-mesenchymal transitionJournal of cellular and molecular medicineMarch 1, 2020Wang X, Xu Z, Sun J, Lv H, Wang Y, Ni Y, Chen S, Hu C, Wang L, Chen W, et al.plates and cultured until approximately 80% confluence, and they were then transfected with GPR30 siRNA (sc‐60743, Santa Cruz Biotechnology) or negative control siRNA (Invitrogen) combined with Lipofectamine 2000 (Invitrogen).

(9) GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoACancersJanuary 25, 2020Rice A, Cortes E, Lachowski D, Oertle P, Matellan C, Thorpe SD, Ghose R, Wang H, Lee DA, Plodinec M, et al.preparation of plasmids for transfections, lyophilised GPER siRNA plasmids (Santa Cruz Biotechnology, sc-60743, Dallas, TX, USA) were resuspended in 330 μL of RNase-free water to make a 10 μM solution. The constitutively

(10) G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell PolarizationFrontiers in cell and developmental biologyJanuary 1, 2020Lachowski D, Cortes E, Matellan C, Rice A, Lee DA, Thorpe SD, Del Río Hernández AE.(H+L) (LI-COR 925-32213, 1/15,000). siRNA targeting GPER was purchased from Santa Cruz Biotechnology (sc-60743). G protein-coupled estrogen receptor agonist (G1) and GPER antagonist (G15) were purchased from Tocris

(11) Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptorOncogeneApril 1, 2019Cortes E, Lachowski D, Rice A, Thorpe SD, Robinson B, Yeldag G, Lee DA, Ghemtio L, Rombouts K, Del Río Hernández AE.every 72 h in all cases. For GPER and HIF-1α knockdowns, siRNA for GPER (Santa Cruz Biotechnology, cat. sc-60743) and siRNA for HIF-1A (cat. Sc-35561, from Santa Cruz Biotechnology USA), respectively, were used to

(12) GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironmentEMBO reportsJanuary 1, 2019Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, Del Río Hernández AE.G1 (cat. 2577), PPT (cat. 1426), ERB041 (cat. 4276), siRNA for GPER (Santa Cruz Biotechnology, cat. sc‐60743). For the experiments using the AsPC1 conditioning media, cells were grown under normal culture media

(13) Chronic BDE-47 Exposure Aggravates Malignant Phenotypes and Chemoresistance by Activating ERK Through ERα and GPR30 in Endometrial CarcinomaFrontiers in oncologyJanuary 1, 2019Zhang F, Peng L, Huang Y, Lin X, Zhou L, Chen J.(sc-29305, Santa Cruz Biotechnology, Inc., Dallas, Texas, US) to silence ERα expression, or with siGPR30 (sc-60743, Santa Cruz Biotechnology, Inc., Dallas, Texas, US) to silence GPR30 expression. Control siRNAs (sc-44230,

(14) The treatment effects of flaxseed-derived secoisolariciresinol diglycoside and its metabolite enterolactone on benign prostatic hyperplasia involve the G protein-coupled estrogen receptor 1Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolismeDecember 1, 2016Ren GY, Chen CY, Chen WG, Huang Y, Qin LQ, Chen LH.(scrambled siRNA) and GPR30 t siRNA were provided by Santa Cruz Biotechnology ( Cat. No. sc-37007, sc-60743). Immunoblotting Proteins extraction and immunoblotting were performed as described previously (Chen

(15) Ultrasound-targeted microbubble destruction of calcium channel subunit α 1D siRNA inhibits breast cancer via G protein-coupled receptor 30Oncology reportsOctober 1, 2016Ji Y, Han Z, Shao L, Zhao Y.

(16) Bisphenol A Induces Migration through a GPER-, FAK-, Src-, and ERK2-Dependent Pathway in MDA-MB-231 Breast Cancer CellsChemical research in toxicologyMarch 21, 2016Castillo Sanchez R, Gomez R, Perez Salazar E.

(17) Estradiol and Estrogen Receptor Agonists Oppose Oncogenic Actions of Leptin in HepG2 CellsPloS oneJanuary 1, 2016Shen M, Shi H.

(18) Estrogen receptor variant ER-α36 is involved in estrogen neuroprotection against oxidative toxicityNeuroscienceDecember 3, 2015Han S, Zhao B, Pan X, Song Z, Liu J, Gong Y, Wang M.

(19) G15 sensitizes epithelial breast cancer cells to doxorubicin by preventing epithelial-mesenchymal transition through inhibition of GPR30American journal of translational researchJanuary 1, 2015Liu Y, Du FY, Chen W, Fu PF, Yao MY, Zheng SS.

(20) GPER functions as a tumor suppressor in triple-negative breast cancer cellsJournal of cancer research and clinical oncologyMay 1, 2014Weißenborn C, Ignatov T, Ochel HJ, Costa SD, Zenclussen AC, Ignatova Z, Ignatov A.

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GPR30 siRNA (h)

GPR30 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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GPR30 siRNA (h) from Santa Cruz Biotechnology, Inc.

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