Nox4 siRNA (r) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNox4 siRNA (r)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-61887
Gene NameNADPH oxidase 4
Quantity10 µM
Speciesrat
NCBI Full Gene NameNADPH oxidase 4
NCBI Gene AliasesKOX, RENOX, KOX-1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunctionFree radical biology & medicineApril 1, 2023Xie J, Lv H, Liu X, Xia Z, Li J, Hong E, Ding B, Zhang W, Chen Y.

(2) Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral HemorrhageFrontiers in cellular neuroscienceJanuary 1, 2020Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y.described (Feng et al., 2015; Lu et al., 2019). Briefly, the rats were deeply anesthetized, and NOX4 siRNA (sc-61887, Santa Cruz Biotechnology, United States) or control scramble siRNA (sc-37007, Santa Cruz Biotechnology,

(3) Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic ratsFree radical biology & medicineNovember 1, 2019Zhang WX, Tai GJ, Li XX, Xu M.

(4) Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cellsVascular pharmacologySeptember 1, 2019Liu X, Qin Z, Liu C, Song M, Luo X, Zhao H, Qian D, Chen J, Huang L.

(5) SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathwayBMC molecular and cell biologyJune 19, 2019Yu MH, Li X, Li Q, Mo SJ, Ni Y, Han F, Wang YB, Tu YX.

(6) Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic ratsScientific reportsAugust 22, 2018Su J, An XR, Li Q, Li XX, Cong XD, Xu M.represent cellular O2−. level. RNA interference of Nox4 Nox4 siRNA was purchased from Santa Cruz (sc-61887). Their targeting sequences were as follows: 5′-AAUUCUCCGAACGUGUCACGU-3′. The scrambled small RNA (5′-AAUUCUCCGAACGUGUCACGU-3′)

(7) H(2)S inhibits angiotensin II-induced atrial Kv1.5 upregulation by attenuating Nox4-mediated ROS generation during atrial fibrillationBiochemical and biophysical research communicationsJanuary 29, 2017Lu G, Xu C, Tang K, Zhang J, Li Q, Peng L, Wang Y, Huang Z, Gao X.

(8) Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial functionBiochimica et biophysica acta. General subjectsJanuary 1, 2017Sun Q, Zhang W, Zhong W, Sun X, Zhou Z.

(9) Reactive oxygen species are involved in insulin-dependent regulation of autophagy in primary rat podocytesThe international journal of biochemistry & cell biologyJune 1, 2016Audzeyenka I, Rogacka D, Piwkowska A, Rychlowski M, Bierla JB, Czarnowska E, Angielski S, Jankowski M.

(10) NADPH oxidase 4 contributes to connective tissue growth factor expression through Smad3-dependent signaling pathwayFree radical biology & medicineMay 1, 2016Liu XH, Zhang QY, Pan LL, Liu SY, Xu P, Luo XL, Zou SL, Xin H, Qu LF, Zhu YZ.

(11) Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neuronsMolecular and cellular neurosciencesJuly 1, 2015Chandrasekaran V, Lea C, Sosa JC, Higgins D, Lein PJ.

(12) Inhibition of NADPH oxidase 4-related signaling by sodium hydrosulfide attenuates myocardial fibrotic responseInternational journal of cardiologyOctober 9, 2013Pan LL, Liu XH, Shen YQ, Wang NZ, Xu J, Wu D, Xiong QH, Deng HY, Huang GY, Zhu YZ.

(13) The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosisFree radical biology & medicineAugust 1, 2013Ni J, Dong Z, Han W, Kondrikov D, Su Y.MRTF-A and Nox4 mRNA. The siRNAs were obtained from Santa Cruz Biotechnology (sc- 43944 for MRTF-A and sc-61887 for Nox4). A silencer negative control siRNA (AM4611, Applied Biosystems, Foster City, CA) was used

(14) Hydrogen peroxide-mediated oxidative stress and collagen synthesis in cardiac fibroblasts: blockade by tanshinone IIAJournal of ethnopharmacologyJanuary 9, 2013Wang P, Zhou S, Xu L, Lu Y, Yuan X, Zhang H, Li R, Fang J, Liu P.

(15) Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4Free radical biology & medicineJanuary 1, 2013Liu XH, Pan LL, Deng HY, Xiong QH, Wu D, Huang GY, Gong QH, Zhu YZ.

(16) Xanthine oxidase mediates hypoxia-inducible factor-2α degradation by intermittent hypoxiaPloS oneJanuary 1, 2013Nanduri J, Vaddi DR, Khan SA, Wang N, Makerenko V, Prabhakar NR.

(17) Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivoFree radical biology & medicineJuly 15, 2012Jiang JX, Chen X, Serizawa N, Szyndralewiez C, Page P, Schröder K, Brandes RP, Devaraj S, Török NJ.

(18) NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in ratsAntioxidants & redox signalingFebruary 15, 2011Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR.for Nox2, Nox4, or scrambled (control) sequences (Santa Cruz Biotechnology; Cat # sc-61838 (Nox2), sc-61887 (Nox4), and sc37007 Scrambled; 100 pmol=mL) using a DharmaFECT-2 (Dharmacon Research) according to the

(19) Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivationArchives of biochemistry and biophysicsJanuary 15, 2011Zhang HS, Sang WW, Ruan Z, Wang YO.

(20) Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidaseFree radical researchJune 1, 2007Peshavariya HM, Dusting GJ, Selemidis S.

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Nox4 siRNA (r)

Nox4 siRNA (r) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Nox4 siRNA (r) from Santa Cruz Biotechnology, Inc.

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