LSD1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemLSD1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-60970
Gene Namelysine (K)-specific demethylase 1A
Quantity10 µM
Specieshuman
NCBI Full Gene Namelysine demethylase 1A
NCBI Gene AliasesAOF2, BHC110, CPRF, KDM1, LSD1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanicsMolecular metabolismOctober 1, 2022Chianese U, Papulino C, Passaro E, Evers TM, Babaei M, Toraldo A, De Marchi T, Niméus E, Carafa V, Nicoletti MM, et al.C6 flow cytometer system (BD Biosciences, New Jersey, U.S.A.). 2.7 shLSD1 transfection shLSD1 vector (Santa Cruz, sc-60970) and the empty vector shSCR (Santa Cruz, sc-108060) were used. 1 μg of each vector was transfected into

(2) Discovery of the antitumor activities of a potent DCN1 inhibitor compound 383 targeting LSD1 in gastric cancerEuropean journal of pharmacologyFebruary 5, 2022Song Z, Gao K, Asmamaw MD, Liu YJ, Zheng YC, Shi XJ, Liu HM.

(3) Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic MechanismsAnalytical cellular pathology (Amsterdam)January 1, 2022Shen Z, Gu Y, Jiang R, Qian H, Li S, Xu L, Gu W, Zuo Y.Japan). 2.4. Transient Transfection The cells were inoculated in six-well plates. LSD1-specific siRNA (sc-60970, Santa Cruz, US) or nontarget-specific control siRNA (sc-37007, Santa Cruz, US) was transiently transfected

(4) LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing CatalaseCellsSeptember 18, 2021Sobczak M, Strachowska M, Gronkowska K, Karwaciak I, Pułaski Ł, Robaszkiewicz A.Cell Signaling Technology (LabJOT, Warsaw, Poland). Anti-CAT ((H-9): sc-271803) antibody, siCAT (sc-45330), siLSD1 (sc-60970) were from Santa Cruz Biotechnology (AMX, Lodz, Poland). 2.2. Monocyte Isolation, Differentiation to

(5) Downregulation of lysine-specific demethylase 1 enhances the sensitivity of hormone-sensitive prostate cancer cells to androgen deprivation therapyOncology lettersFebruary 1, 2021Wang M, Liu X, Chen Z, Zhang L, Weng X.cells were transfected with 10 nM of small interfering (si)RNA for LSD1 (siRNA-LSD1-LNCaP; cat. no. sc-60970; Santa Cruz Biotechnology) or 10 nM of scrambled siRNA control using Lipofectamine® 2000 (cat. no. 11668027;

(6) Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repressionNucleic acids researchSeptember 18, 2020Pezone A, Taddei ML, Tramontano A, Dolcini J, Boffo FL, De Rosa M, Parri M, Stinziani S, Comito G, Porcellini A, et al.

(7) Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockadeOncogeneJanuary 1, 2019Qin Y, Vasilatos SN, Chen L, Wu H, Cao Z, Fu Y, Huang M, Vlad AM, Lu B, Oesterreich S, et al.

(8) Lysine-specific demethylase 1 cooperates with BRAF-histone deacetylase complex 80 to enhance HIV-1 Tat-mediated transactivationVirus genesOctober 1, 2018Liu Y, Zhou D, Qi D, Feng J, Liu Z, Hu Y, Shen W, Liu C, Kong X.

(9) Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytesAutophagyJanuary 1, 2018Song H, Feng X, Zhang M, Jin X, Xu X, Wang L, Ding X, Luo Y, Lin F, Wu Q, et al.

(10) Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progressionOncogeneJanuary 5, 2017Cao C, Vasilatos SN, Bhargava R, Fine JL, Oesterreich S, Davidson NE, Huang Y.

(11) The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin stateScientific reportsMay 13, 2016Alarcon V, Hernández S, Rubio L, Alvarez F, Flores Y, Varas-Godoy M, De Ferrari GV, Kann M, Villanueva RA, Loyola A.either control siRNA (Silencer negative control #1 siRNA, Ambion, Life Technologies), human LSD1 siRNA (sc-60970, Santa Cruz Biotechnology), or human Set1A siRNA (sc-76484, Santa Cruz) was transfected with Lipofectamine. For

(12) Puerarin suppresses high glucose-induced MCP-1 expression via modulating histone methylation in cultured endothelial cellsLife sciencesJune 1, 2015Han P, Gao D, Zhang W, Liu S, Yang S, Li X.

(13) Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cellsCarcinogenesisJune 1, 2013Vasilatos SN, Katz TA, Oesterreich S, Wan Y, Davidson NE, Huang Y.

(14) The combined effect of retinoic acid and LSD1 siRNA inhibition on cell death in the human neuroblastoma cell line SH-SY5YCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2013Xu G, Xiao Y, Hu J, Xing L, Zhao O, Wu Y.

(15) Reversible methylation of promoter-bound STAT3 by histone-modifying enzymesProceedings of the National Academy of Sciences of the United States of AmericaDecember 14, 2010Yang J, Huang J, Dasgupta M, Sears N, Miyagi M, Wang B, Chance MR, Chen X, Du Y, Wang Y, et al.

(16) LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancerScientific reportsJanuary 1, 0001"Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, et al."hours before stimulating cells. Forward transfection reactions were performed with 40 nM human siRNA (sc-60970) and mock siRNA (sc-36869) (Santa Cruz Biotechnology) using Lipofectamine 2000 (Invitrogen). Vector

(17) "The Histone Lysine-specific Demethylase 1 Inhibitor, SP2509 Exerts Cytotoxic Effects against Renal Cancer Cells through Downregulation of Bcl-2 and Mcl-1"Journal of cancer preventionJanuary 1, 0001"Wu K, Woo SM, Kwon TK."

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LSD1 siRNA (h)

LSD1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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LSD1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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