Cryopyrin siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCryopyrin siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-45469
Gene NameNLR family, pyrin domain containing 3
Quantity10 µM
Specieshuman
NCBI Full Gene NameNLR family pyrin domain containing 3
NCBI Gene AliasesAGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCAS1, FCU, KEFH, MWS, NALP3, PYPAF1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR-mutated and overexpressed oral canceriScienceMarch 17, 2023Lin YC, Hua CH, Lu HM, Huang SW, Chen Y, Tsai MH, Lin FY, Canoll P, Chiu SC, Huang WH, et al.

(2) Nicotine exacerbates atherosclerosis and plaque instability via NLRP3 inflammasome activation in vascular smooth muscle cellsTheranosticsJanuary 1, 2023An J, Ouyang L, Yu C, Carr SM, Ramprasath T, Liu Z, Song P, Zou MH, Ding Y.(BML-CM110-0100) was from Enzo Life Sciences. Scr siRNA (sc-37007) and siRNAs targeting human NLRP3 (sc-45469), human ASC (sc-37281), human Cathepsin B (sc-29238) were from Santa Cruz. LysoTracker® Red DND-99 (L-7528)

(3) IL-23 production in human macrophages is regulated negatively by tumor necrosis factor α-induced protein 3 and positively by specificity protein 1 after stimulation of the toll-like receptor 7/8 signaling pathwayHeliyonFebruary 1, 2022Yamaguchi R, Sakamoto A, Yamaguchi R, Haraguchi M, Narahara S, Sugiuchi H, Yamaguch Y.(catalog#sc-72044) (50nM), TRAF6 (catalog#sc-36717) (50nM), OAS-1 (catalog#sc-61241) (50nM), and cryopyrin (catalog#sc-45469) (50nM) or control siRNA-A (catalog#sc-44236) (Santa Cruz Biotechnology, Santa Cruz, CA); Lipofectamine

(4) Oxymatrine attenuates oxidized low‑density lipoprotein‑induced HUVEC injury by inhibiting NLRP3 inflammasome‑mediated pyroptosis via the activation of the SIRT1/Nrf2 signaling pathwayInternational journal of molecular medicineOctober 1, 2021Jin X, Fu W, Zhou J, Shuai N, Yang Y, Wang B.purchased from Cell Signaling Technology, Inc. Small interfering (si)RNA for NLRP3 (siNLRP3; cat. no. sc-45469) and control siRNA-B (siNC; cat. no. sc-44230), siRNA for SIRT1 (siSIRT1; cat. no. sc-40986) and control siRNA-A

(5) GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsisAgingSeptember 28, 2021Zhang W, Wang W, Xu M, Xie H, Pu Z.5′-CATGGCTTACATCATCATCT-3′ and 5′-CTACAGAGTAGCAGTTTCCC-3′) or the si-GPR43 (sc-77339, Santa Cruz Biotechnology), si-NLRP3 (sc-45469, Santa Cruz Biotechnology), si-p47phox (sc-29422, Santa Cruz Biotechnology) and NOX-1 siRNAs (20 nmol/ml,

(6) Exposure to mono (2-ethylhexyl) phthalate facilitates apoptosis and pyroptosis of human endometrial microvascular endothelial cells through NLRP3 inflammasomeJournal of applied toxicology : JATMay 1, 2021An L.

(7) Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansionProceedings of the National Academy of Sciences of the United States of AmericaMarch 9, 2021Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, et al.

(8) Activation of NLRP3 inflammasome in hepatocytes after exposure to cobalt nanoparticles: The role of oxidative stressToxicology in vitro : an international journal published in association with BIBRADecember 1, 2020Feng S, Zhang Z, Mo Y, Tong R, Zhong Z, Chen Z, He D, Wan R, Gao M, Mo Y, et al.

(9) Nrf2/HO-1 partially regulates cytoprotective effects of carbon monoxide against urban particulate matter-induced inflammatory responses in oral keratinocytesCytokineSeptember 1, 2020Cheng CY, Vo TTT, Lin WN, Huang HW, Chuang CC, Chu PM, Lee IT.

(10) Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cellsParticle and fibre toxicologyAugust 10, 2020Wu R, Högberg J, Adner M, Ramos-Ramírez P, Stenius U, Zheng H.

(11) Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cellsAgingApril 22, 2020Bai Z, Liu W, He D, Wang Y, Yi W, Luo C, Shen J, Hu Z.

(12) ROS-induced NLRP3 inflammasome priming and activation mediate PCB 118- induced pyroptosis in endothelial cellsEcotoxicology and environmental safetyFebruary 1, 2020Long Y, Liu X, Tan XZ, Jiang CX, Chen SW, Liang GN, He XM, Wu J, Chen T, Xu Y.

(13) Relaxin Can Mediate Its Anti-Fibrotic Effects by Targeting the Myofibroblast NLRP3 Inflammasome at the Level of Caspase-1Frontiers in pharmacologyJanuary 1, 2020Pinar AA, Yuferov A, Gaspari TA, Samuel CS.four separate individual siRNAs—one control siRNA (#sc-37007), and three siRNAs each targeting NLRP3 (#sc-45469), ASC (#37281), or caspase-1 (#29235) were prepared separately (all purchased from Santa Cruz Biotechnology,

(14) Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritisArthritis research & therapyDecember 23, 2019Chen Z, Zhong H, Wei J, Lin S, Zong Z, Gong F, Huang X, Sun J, Li P, Lin H, et al.

(15) NLRP3 inflammasome mediate palmitate-induced endothelial dysfunctionLife sciencesDecember 15, 2019Xing JH, Li R, Gao YQ, Wang MY, Liu YZ, Hong J, Dong JZ, Gu HP, Li L.

(16) Overexpression of miR‑200a‑3p promoted inflammation in sepsis‑induced brain injury through ROS‑induced NLRP3International journal of molecular medicineNovember 1, 2019Yu J, Chen J, Yang H, Chen S, Wang Z.(5′-TAACACTGTCTGGTAACGATGT-3′ and 5′-GCGGGTCACCTTTGAACATC-3′), 100 ng of small interfering RNA (si)-NLRP3 (cat. no. sc-45469; Santa Cruz Biotechnology, Inc.) plasmid and 100 ng of negative plasmid (5′-TTCTCCGAACGTGTCACGT-3′ and

(17) Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis via regulation of ROS/NLRP3/Caspase-1 signaling pathwayInflammation research : official journal of the European Histamine Research Society ... [et al.]September 1, 2019Tang YS, Zhao YH, Zhong Y, Li XZ, Pu JX, Luo YC, Zhou QL.

(18) Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescenceJournal of cellular physiologyMay 1, 2019Sun C, Diao Q, Lu J, Zhang Z, Wu D, Wang X, Xie J, Zheng G, Shan Q, Fan S, et al.

(19) NLRP3 inflammasome promotes diabetes-induced endothelial inflammation and atherosclerosisDiabetes, metabolic syndrome and obesity : targets and therapyJanuary 1, 2019Wan Z, Fan Y, Liu X, Xue J, Han Z, Zhu C, Wang X.

(20) SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomesCell death discoveryJanuary 1, 2019Shi CS, Nabar NR, Huang NN, Kehrl JH.mCherry-Galectin 3 plasmid made by removing the GFP from the ptf-Galectin 3 vector. Pooled siRNAs targeting NLRP3 (sc-45469), ASC (sc-37281), GFP (sc-45924), and a scrambled control (sc-37007) were purchased from Santa Cruz Biotechnology

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