AMPKα1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemAMPKα1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29673
Quantity10 µM
Gene Nameprotein kinase, AMP-activated, alpha 1 catalytic subunit
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene Nameprotein kinase AMP-activated catalytic subunit alpha 1
NCBI Gene AliasesAMPK, AMPK alpha 1, AMPKa1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between polyP and the activity of AMPKMolecular MetabolismJanuary 1, 2025Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, et al.Master Mix was acquired from QIAGEN (Hilden, Germany). The scramble siRNA (sc-37007) and AMPKα1 siRNA (sc-29673) were acquired from Santa Cruz Biotechnology (Dallas, Texas, USA). All reagents and materials used in

(2) Mitochondria-encoded peptide MOTS-c participates in plasma membrane repair by facilitating the translocation of TRIM72 to membraneTheranosticsAugust 19, 2024Hong Jia, Lyu-Chen Zhou, Yong-Feng Chen, Wei Zhang, Wei Qi, Peng Wang, Xiao Huang, Jian-Wei Guo, Wai-Fang Hou, Ran-Ran Zhang, et al.ELISA kits for MOTS-c (Cat# CEX132Hu) were provided by Cloud-Clone (Katy, USA). AMPKα1-siRNA (Cat# sc-29673), and Mouse and rabbit antibodies against TRIM72 were purchased from Santa Cruz Biotechnology (Cat#

(3) AMPK inhibition induces MCL1 mRNA destabilization via the p38 MAPK/miR-22/HuR axis in chronic myeloid leukemia cellsBiochemical pharmacologyMarch 1, 2023Lee YC, Chiou JT, Chang LS.

(4) A Hydrodistillate of Gynostemma pentaphyllum and Damulin B Prevent Cisplatin-Induced Nephrotoxicity In Vitro and In Vivo via Regulation of AMPKα1 TranscriptionNutrientsNovember 24, 2022Song M, Kim M, Hoang DH, Kovale LM, Lee J, Kim Y, Lee C, Hong J, Park S, Choe W, et al.

(5) PHLPP1 regulates CFTR activity and lumen expansion through AMPKDevelopment (Cambridge, England)October 15, 2022Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, et al.5′-UGUAGAAUAUGGAGACUAA-3′; PHLPP2, 5′-GAACUUGUCCCAUAAUU-3′. AMPK siRNA was purchased from Santa Cruz (sc-29673). Immunofluorescence and confocal microscopy Cysts and transwells were fixed with 4% methanol-free

(6) Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activationThe Journal of biological chemistryJuly 1, 2022Ma S, Dong Z, Huang Y, Liu JY, Zhang JT.

(7) Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD-fed miceBritish journal of pharmacologyApril 1, 2022Yang Q, Ma Q, Xu J, Liu Z, Mao X, Zhou Y, Cai Y, Da Q, Hong M, Weintraub NL, et al.HUVECs were transfected at 70% confluence with siRNA targeting human PRKAA1 (PRKAA1 siRNA [siPRKAA1], sc‐29673; Santa Cruz Biotechnology) or non‐targeting negative control (Control siRNA [siCTRL], sc‐37007; Santa Cruz Biotechnology

(8) Ginkgolide B Protects Against Ischemic Stroke via Targeting AMPK/PINK1Frontiers in pharmacologyJanuary 1, 2022Cao Y, Yang L, Cheng H.RNA SH-SY5Y cells were subjected to transient transfection with 100 nM siRNAs targeting AMPKα1/α2 (sc-29673 and sc-38923) or non-silencing control siRNA (scram) (sc-37007) (Santa Cruz Biotechnology, Santa Cruz,

(9) Fatty acid transport protein-5 (FATP5) deficiency enhances hepatocellular carcinoma progression and metastasis by reprogramming cellular energy metabolism and regulating the AMPK-mTOR signaling pathwayOncogenesisNovember 12, 2021Wang MD, Wang NY, Zhang HL, Sun LY, Xu QR, Liang L, Li C, Huang DS, Zhu H, Yang T.

(10) Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXRα signal in an AMPK-dependent mannerJournal of physiology and biochemistryAugust 1, 2021Chen X, Zou D, Chen X, Wu H, Xu D.purchased from Merck Millipore (Billerica, MA, USA). The control siRNA (sc-37007), AMPK alpha 1 siRNA (sc-29673), and AMPK alpha 2 siRNA (sc-38923) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA).

(11) Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stressesJournal of receptor and signal transduction researchAugust 1, 2021Ma X, Zhang J, Wu Z, Wang X.

(12) Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathwayExperimental and therapeutic medicineMarch 1, 2021Zhao B, Li GP, Peng JJ, Ren LH, Lei LC, Ye HM, Wang ZY, Zhao S.Nrf2-specific siRNA (si-Nrf2; 100 nM; cat. no. sc-37030), AMPK-specific siRNA (si-AMPK; 100 nM; cat. no. sc-29673) or scrambled siRNA (100 nM; cat. no. sc-37007) as the negative control (Santa Cruz Biotechnology, Inc.)

(13) RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in colorectal cancer cellsJournal of ethnopharmacologyFebruary 10, 2021Wang J, Wang J, Li L, Feng L, Wang YR, Wang Z, Tan NH.

(14) AMPKα1 Regulates Lung and Breast Cancer Progression by Regulating TLR4-Mediated TRAF6-BECN1 Signaling AxisCancersNovember 6, 2020Kim MJ, Min Y, Son J, Kim JY, Lee JS, Kim DH, Lee KY.

(15) Metformin suppresses HIF-1α expression in cancer-associated fibroblasts to prevent tumor-stromal cross talk in breast cancerFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2020Shao S, Zhao L, An G, Zhang L, Jing X, Luo M, Li W, Meng D, Ning Q, Zhao X, et al.

(16) HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma modelsThe Journal of clinical investigationJuly 1, 2020Nguyen TTT, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela A, Humala N, Mahajan A, et al.

(17) Targeting PI3K and AMPKα Signaling Alone or in Combination to Enhance Radiosensitivity of Triple Negative Breast CancerCellsMay 19, 2020Johnson J, Chow Z, Napier D, Lee E, Weiss HL, Evers BM, Rychahou P.

(18) Disulfide Cleavage in a Dimeric Epipolythiodioxopiperazine Natural Product Diminishes Its Apoptosis-Inducing Effect but Enhances Autophagy in Tumor CellsJournal of natural productsMarch 27, 2020Li E, Hou B, Gao Q, Xu Y, Zhang C, Liu X, Jiang X, Che Y.

(19) A diterpene derivative enhanced insulin signaling induced by high glucose level in HepG2 cellsJournal of natural medicinesMarch 1, 2020Hou P, Qu Y, Liao Z, Zhao S, Feng Y, Zhang J.

(20) Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial CellsOxidative medicine and cellular longevityJanuary 1, 2020Bai X, Jia X, Lu Y, Zhu L, Zhao Y, Cheng W, Shu M, Jin S.

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AMPKα1 siRNA (h)

AMPKα1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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AMPKα1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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