Rock-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRock-2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29474
Gene NameRho-associated coiled-coil containing protein kinase 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameRho associated coiled-coil containing protein kinase 2
NCBI Gene AliasesROCK-II
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Induction of adipocyte thermogenic program by Rho-associated coiled-coil containing kinase 2iScienceApril 17, 2026Haw-Chih Tai, Xiaoou Li, Christina J. Park, Altayeb Alshaikh, Brian Yu, Daiqing Chen, Phetcharat Chen, James K. Liaosc-29381 ROCK1 siRNA (h),Santa Cruz Biotechnology,Cat# sc-29473 ROCK2 siRNA (h),Santa Cruz Biotechnology,Cat#sc-29474 "Silencer Select Pre-Designed siRNA, mouse Foxo1",Thermo Fisher Scientific,Cat# 4390771 ,, Software

(2) Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cellseLifeApril 19, 2023Julieta Martino, Sebastián Omar Siri, Nicolás Luis Calzetta, Natalia Soledad Paviolo, Cintia Garro, Maria F Pansa, Sofía Carbajosa, Aaron C Brown, José Luis Bocco, Israel Gloger, et al.cells were transfected for a total of 48 hr. siROCK1 (#sc-29473 Santa Cruz Biotechnology) and siROCK2 (#sc-29474, Santa Cruz Biotechnology) were used at 100 nM. siEMI1 (#sc-37611 Santa Cruz Biotechnology) and siCITK

(3) ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytesProceedings of the National Academy of Sciences of the United States of AmericaJanuary 17, 2023Tlili A, Pintard C, Hurtado-Nedelec M, Liu D, Marzaioli V, Thieblemont N, Dang PM, El-Benna J.serum and 1% penicillin/streptomycin. Cells were transfected with control (sc-37007) or ROCK2 siRNA (sc-29474) or ROCK1 (sc-29473) using reagents and protocol provided by Santa Cruz Biotechnology. After 48 h, the

(4) Numb inhibits migration and promotes proliferation of colon cancer cells via RhoA/ROCK signaling pathway repressionExperimental cell researchFebruary 15, 2022Yang Y, Li L, He H, Shi M, He L, Liang S, Qi J, Chen W.

(5) Oroxylin a Attenuates Limb Ischemia by Promoting Angiogenesis via Modulation of Endothelial Cell MigrationFrontiers in pharmacologyJanuary 1, 2021Zhang L, Chen L, Li C, Shi H, Wang Q, Yang W, Fang L, Leng Y, Sun W, Li M, et al.kit™ (#BK030) was bought from Cytoskeleton (CO, United States). ROCK-II small interfering RNA (siRNA) (sc-29474), scrambled siRNA (sc-37007), and siRNA transfection reagent (sc-29528) were obtained from Santa Cruz Biotechnology

(6) Roles of RAGE/ROCK1 Pathway in HMGB1-Induced Early Changes in Barrier Permeability of Human Pulmonary Microvascular Endothelial CellFrontiers in immunologyJanuary 1, 2021Zhao MJ, Jiang HR, Sun JW, Wang ZA, Hu B, Zhu CR, Yin XH, Chen MM, Ma XC, Zhao WD, et al.Phalloidin-iFluor 594 Conjugate was obtained from Absin Bioscience (Shanghai, China). ROCK1/2 siRNA (SC-29473/SC-29474), RAGE siRNA (SC-36374) and negative control siRNA were from Santa Cruz Biotechnology Co., Ltd (Shanghai,

(7) The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 proteinBMC cancerNovember 4, 2020Na T, Zhang K, Yuan BZ.

(8) Engineering blood outgrowth endothelial cells to optimize endothelial nitric oxide synthase and extracellular matrix production for coating of blood contacting surfacesActa biomaterialiaJune 1, 2020Yuan Y, Khan S, Stewart DJ, Courtman DW.

(9) LINC01638 lncRNA mediates the postoperative distant recurrence of bladder cancer by upregulating ROCK2Oncology lettersNovember 1, 2019Yuan S, Luan X, Han G, Guo K, Wang S, Zhang X.Ltd using the pcDNA3.1 vector as the primary vector. ROCK2 small interfering (si)RNA (human; cat. no. sc-29474) and negative control (NC) siRNA (cat. no. sc-37007) were purchased from Santa Cruz Biotechnology, Inc.

(10) Oxygen-Glucose Deprivation/Reoxygenation Induces Human Brain Microvascular Endothelial Cell Hyperpermeability Via VE-Cadherin Internalization: Roles of RhoA/ROCK2Journal of molecular neuroscience : MNSeptember 1, 2019Chen J, Sun L, Ding GB, Chen L, Jiang L, Wang J, Wu J.

(11) Role of phospho-ezrin in differentiating thyroid carcinomaScientific reportsApril 17, 2019Lathika LM, Nair JKKM, Saritha VN, Sujathan K, Sreeja S.

(12) ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial CellsInternational journal of molecular sciencesMarch 16, 2019Takeda Y, Matoba K, Kawanami D, Nagai Y, Akamine T, Ishizawa S, Kanazawa Y, Yokota T, Utsunomiya K.Predesigned human small interfering RNA (siRNA) duplexes against ROCK1 (Cat# sc-29473), ROCK2 (Cat# sc-29474), MCP-1 (Cat# sc-43914), E-selectin (Cat# sc-29296) and control siRNA (Cat# sc-37007) also were purchased

(13) Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertensionPloS oneJanuary 1, 2018Wilson JL, Warburton R, Taylor L, Toksoz D, Hill N, Polgar P.

(14) Rutin Prevents High Glucose-Induced Renal Glomerular Endothelial Hyperpermeability by Inhibiting the ROS/Rhoa/ROCK Signaling PathwayPlanta medicaSeptember 1, 2016Wang X, Zhao X, Feng T, Jin G, Li Z.

(15) A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cellsScientific reportsAugust 30, 2016Al-Ghabkari A, Deng JT, McDonald PC, Dedhar S, Alshehri M, Walsh MP, MacDonald JA.(CASMC, CC-2583; Lonza; Allendale, NJ) were cultured as previously described20. Human ROCKII siRNA (sc-29474) and scrambled siRNA (sc-37007) were purchased from Santa Cruz Biotechnology. CASMCs were transfected

(16) F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signallingNature communicationsJanuary 27, 2016Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, et al.sc-29354 (50 nM), PECAM-1 sc-29445 (50 nM), LARG sc-41800 (50 nM), Rock-1 (sc-29473) (50 nM), Rock-2b (sc-29474) (50 nM),and scrambled non-silencing siRNA were purchased from (Santa Cruz Biotechnology, Santa Cruz,

(17) MiR-124 Promote Neurogenic Transdifferentiation of Adipose Derived Mesenchymal Stromal Cells Partly through RhoA/ROCK1, but Not ROCK2 Signaling PathwayPloS oneJanuary 1, 2016Wang Y, Wang D, Guo D.

(18) Sevoflurane prevents lipopolysaccharide-induced barrier dysfunction in human lung microvascular endothelial cells: Rho-mediated alterations of VE-cadherinBiochemical and biophysical research communicationsDecember 4, 2015Huang Y, Tan Q, Chen R, Cao B, Li W.

(19) CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axisFree radical biology & medicineDecember 1, 2015Hwang S, Lee HJ, Kim G, Won KJ, Park YS, Jo I.

(20) Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathwayScientific reportsNovember 16, 2015Li S, Dang Y, Zhou X, Huang B, Huang X, Zhang Z, Kwan YW, Chan SW, Leung GP, Lee SM, et al.RNA interference The synthetic siRNA targeting ERα (sc-29305, Santa Cruz Biotechnology) and ROCK-II siRNA (h) (sc-29474, Santa Cruz Biotechnology) were used at the final concentration of 100 nM to silence ERα and ROCK-II,

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Rock-2 siRNA (h)

Rock-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Rock-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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