Keap1 siRNA (h) from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Piperlongumine conjugates induce targeted protein degradationCell chemical biologyFebruary 16, 2023Pei J, Xiao Y, Liu X, Hu W, Sobh A, Yuan Y, Zhou S, Hua N, Mackintosh SG, Zhang X, et al.

(2) AF8c, a Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer CellsCancersJune 21, 2022Jeong S, Farag AK, Yun HK, Jeong YA, Kim DY, Jo MJ, Park SH, Kim BR, Kim JL, Kim BG, et al.

(4) Acacetin exerts antioxidant potential against atherosclerosis through Nrf2 pathway in apoE(-/-) MiceJournal of cellular and molecular medicineJanuary 1, 2021Wu Y, Song F, Li Y, Li J, Cui Y, Hong Y, Han W, Wu W, Lakhani I, Li G, et al.

(6) SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarateNature communicationsOctober 2, 2020Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, et al.

(7) NRF2 Augments Epidermal Antioxidant Defenses and Promotes AtopyJournal of immunology (Baltimore, Md. : 1950)August 15, 2020Ogawa T, Ishitsuka Y, Nakamura Y, Kubota N, Saito A, Fujisawa Y, Watanabe R, Okiyama N, Suga Y, Roop DR, et al.

(10) Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin InflammationThe American journal of pathologyMarch 1, 2020Ogawa T, Ishitsuka Y, Inoue S, Nakamura Y, Saito A, Okiyama N, Fujisawa Y, Furuta J, Watanabe R, Fujimoto M.

(11) A loop involving NRF2, miR-29b-1-5p and AKT, regulates cell fate of MDA-MB-231 triple-negative breast cancer cellsJournal of cellular physiologyFebruary 1, 2020De Blasio A, Di Fiore R, Pratelli G, Drago-Ferrante R, Saliba C, Baldacchino S, Grech G, Scerri C, Vento R, Tesoriere G.

(12) PGK1 depletion activates Nrf2 signaling to protect human osteoblasts from dexamethasoneCell death & diseaseNovember 26, 2019Liang J, Zhang XY, Zhen YF, Chen C, Tan H, Hu J, Tan MS.

(13) Overexpression of miR‑200a‑3p promoted inflammation in sepsis‑induced brain injury through ROS‑induced NLRP3International journal of molecular medicineNovember 1, 2019Yu J, Chen J, Yang H, Chen S, Wang Z.plasmids (5′-ATTGTGACAGACCATTGCTACA-3′) and 100 ng of si-Keap1 (5′-TGGGGTCGTCGGTCTAGGG-3′; cat. no. sc-43878; Santa Cruz Biotechnology, Inc.), 100 ng of si-Nrf2 (5′-AGTAGTACTACCTGAACCTC-3′; cat. no. sc-37030;

(16) Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogrammingNature communicationsAugust 29, 2018Olagnier D, Brandtoft AM, Gunderstofte C, Villadsen NL, Krapp C, Thielke AL, Laustsen A, Peri S, Hansen AL, Bonefeld L, et al.

(18) Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathwayEuropean journal of medicinal chemistryFebruary 25, 2018Lu M, Liu T, Jiao Q, Ji J, Tao M, Liu Y, You Q, Jiang Z.

(19) Autophagy regulates vinorelbine sensitivity due to continued Keap1-mediated ROS generation in lung adenocarcinoma cellsCell death discoveryJanuary 1, 2018Wu YW, Lin CF, Lin YS, Su WC, Chiu WH.Health, Bethesda, MD, USA). Transfection Keap1 expression was silenced using commercialized siRNA (sc-43878) from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Transfection was performed using electroporation,

(20) Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cellsOncotargetSeptember 19, 2017Yong HJ, Park JS, Lee Jeong A, Han S, Lee S, Ka HI, Sumiyasuren B, Joo HJ, So SJ, Park JY, et al.

Keap1 siRNA (h)