MDR1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMDR1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29395
Gene NameATP-binding cassette, sub-family B (MDR/TAP), member 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameATP binding cassette subfamily B member 1
NCBI Gene AliasesABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, p-170
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Long non-coding RNA LUCAT1 regulates the RAS pathway to promote the proliferation and invasion of malignant glioma cells through ABCB1Experimental cell researchDecember 15, 2022Wu X, Song L, Chen X, Zhang Y, Li S, Tang X.

(2) Galectin-1 confers resistance to doxorubicin in hepatocellular carcinoma cells through modulation of P-glycoprotein expressionCell death & diseaseJanuary 24, 2022Carabias P, Espelt MV, Bacigalupo ML, Rojas P, Sarrias L, Rubin A, Saffioti NA, Elola MT, Rossi JP, Wolfenstein-Todel C, et al.were selected by puromycin resistance. P-gp silencing experiments were performed with MDR1 siRNA (h) (sc-29395, Santa Cruz Biotechnology, Inc.), a target-specific 19–25 nt siRNA. Control siRNA-A (sc-37007, Santa Cruz Biotechnology, Inc

(3) PXR-ABC drug transporters/CYP-mediated ursolic acid transport and metabolism in vitro and vivoArchiv der PharmazieSeptember 1, 2020Jinhua W, Ying Z, Yuhua L.

(4) Z-guggulsterone regulates MDR1 expression mainly through the pregnane X receptor-dependent manner in human brain microvessel endothelial cellsEuropean journal of pharmacologyMay 5, 2020Xu HB, Tang ZQ, Wang J, Kong PS.

(5) An inhibitory antibody targeting carbonic anhydrase XII abrogates chemoresistance and significantly reduces lung metastases in an orthotopic breast cancer model in vivoInternational journal of cancerOctober 15, 2018von Neubeck B, Gondi G, Riganti C, Pan C, Parra Damas A, Scherb H, Ertürk A, Zeidler R.

(6) Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulationOncotargetJune 7, 2016Aldonza MB, Hong JY, Alinsug MV, Song J, Lee SK.

(7) Preclinical Investigations of PM01183 (Lurbinectedin) as a Single Agent or in Combination with Other Anticancer Agents for Clear Cell Carcinoma of the OvaryPloS oneJanuary 1, 2016Takahashi R, Mabuchi S, Kawano M, Sasano T, Matsumoto Y, Kuroda H, Kozasa K, Hashimoto K, Sawada K, Kimura T.

(8) P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseasesCancer medicineOctober 1, 2015Yoshimori M, Takada H, Imadome K, Kurata M, Yamamoto K, Koyama T, Shimizu N, Fujiwara S, Miura O, Arai A.

(9) Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signalingOncotargetAugust 14, 2015Harazono Y, Kho DH, Balan V, Nakajima K, Hogan V, Raz A.minimum peptide identification probability. siRNA against Na+/K+-ATPase alpha(sc-43956) and Mdr-1 (sc-29395), and control siRNA (sc-37007) (Santa Cruz Biotechnology) were transfected into each cells using Lipofectamine

(10) MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cellsToxicological sciences : an official journal of the Society of ToxicologyOctober 1, 2014Wen X, Gibson CJ, Yang I, Buckley B, Goedken MJ, Richardson JR, Aleksunes LM.

(11) Association of ABCB1, β tubulin I, and III with multidrug resistance of MCF7/DOC subline from breast cancer cell line MCF7Tumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineSeptember 1, 2014Li W, Zhai B, Zhi H, Li Y, Jia L, Ding C, Zhang B, You W.

(12) Acetaminophen inhibits intestinal p-glycoprotein transport activityJournal of pharmaceutical sciencesOctober 1, 2013Novak A, Carpini GD, Ruiz ML, Luquita MG, Rubio MC, Mottino AD, Ghanem CI.

(13) Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancerMolecular cancer therapeuticsJanuary 1, 2013Song B, Liu XS, Rice SJ, Kuang S, Elzey BD, Konieczny SF, Ratliff TL, Hazbun T, Chiorean EG, Liu X.transfected with MegaTran (Origene) as described by the manufacturer. The cFos (sc-29221) and MDR1 (sc-29395) siRNAs were purchased from Santa Cruz Biotechnology and transfected with Oligofectamine (Invitrogen)

(14) Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptorPLoS neglected tropical diseasesJanuary 1, 2012Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.accumulation experiments were repeated in HepG2 cells transfected with a siRNA against human P-gp (sc-29395, Santa Cruz) or with a control non-silencing siRNA (Control siRNA-A, sc-37007, Santa Cruz). Cells were

(15) C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell lineEuropean journal of pharmacologyDecember 15, 2010Nishanth RP, Ramakrishna BS, Jyotsna RG, Roy KR, Reddy GV, Reddy PK, Reddanna P.

(16) Molecular mechanism of chemoresistance by astrocyte elevated gene-1Cancer researchApril 15, 2010Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D.

(17) Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell lineCancer chemotherapy and pharmacologyApril 1, 2010Roy KR, Reddy GV, Maitreyi L, Agarwal S, Achari C, Vali S, Reddanna P.

(18) Troglitazone reverses the multiple drug resistance phenotype in cancer cellsDrug design, development and therapySeptember 21, 2009Davies GF, Juurlink BH, Harkness TA.

(19) Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoproteinBiochemical and biophysical research communicationsApril 18, 2008Kim YK, Kim NH, Hwang JW, Song YJ, Park YS, Seo DW, Lee HY, Choi WS, Han JW, Kim SN.

(20) The multidrug transporter P-glycoprotein: a mediator of melanoma invasion?The Journal of investigative dermatologyApril 1, 2008Colone M, Calcabrini A, Toccacieli L, Bozzuto G, Stringaro A, Gentile M, Cianfriglia M, Ciervo A, Caraglia M, Budillon A, et al.

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MDR1 siRNA (h)

MDR1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MDR1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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