TGase2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTGase2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37514
Gene Nametransglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
Quantity10 µM
Specieshuman
NCBI Full Gene Nametransglutaminase 2
NCBI Gene AliasesG(h), TG(C), TGC, hTG2, tTG
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoidCell death & diseaseJune 13, 2023Qin XY, Furutani Y, Yonezawa K, Shimizu N, Kato-Murayama M, Shirouzu M, Xu Y, Yamano Y, Wada A, Gailhouste L, et al.

(2) Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cellsDrug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapyMarch 1, 2023Li X, Ma Y, Wu J, Ni M, Chen A, Zhou Y, Dai W, Chen Z, Jiang R, Ling Y, et al.

(3) The transglutaminase 2 cancer cell survival factor maintains mTOR activity to drive an aggressive cancer phenotypeMolecular CarcinogenesisJanuary 1, 2023Xi Chen, Gautam Adhikary, John J. Newland, Wen Xu, Emily Ma, Warren Naselsky, Richard L. EckertM-003008–03-0005) was obtained from Dharmacon (Lafayyette, CO). Control-siRNA (sc-37007) and human TG2-siRNA (sc-37514) were purchased from Santa Cruz (Dallas, TX). The TG2 inhibitor NC9 was provided by Dr. Jeffrey Keilor

(4) Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancerThe Journal of biological chemistryAugust 1, 2022Condello S, Prasad M, Atwani R, Matei D.

(5) Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotypeMolecular CarcinogenesisJune 1, 2022Warren Naselsky, Gautam Adhikary, Suruchi Shrestha, Xi Chen, Geraldine Ezeka, Wen Xu, Joseph S Friedberg, Richard L. Eckertanti-mouse IgG secondary antibody (A-21202) was from ThermoFisher Scientific (Waltham, MA). TG2-siRNA (sc-37514) was obtained from Santa Cruz Biotechnology (Dallas, TX). Control- (D-001206-13-20), HGF- (M-006050-01-0005)

(6) Transglutaminase 2 mediates UVB-induced matrix metalloproteinase-1 expression by inhibiting nuclear p65 degradation in dermal fibroblastsExperimental dermatologyMay 1, 2022Lee SJ, Lee KB, Hong AY, Son YH, Lee DH, Jeong EM, Kim IG.

(7) Double-Stranded RNA Enhances Matrix Metalloproteinase-1 and -13 Expressions through TLR3-Dependent Activation of Transglutaminase 2 in Dermal FibroblastsInternational journal of molecular sciencesFebruary 28, 2022Hong AY, Lee SJ, Lee KB, Shin JW, Jeong EM, Kim IG.GFP (used as control siRNA) and TG2 siRNAs (Santa Cruz Biotechnology, Dallas, TX, USA, sc-45924 and sc-37514) were transfected using RNAiMAX (Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA) according to

(8) Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in DiabetesInternational journal of molecular sciencesJanuary 11, 2022Seo JA, Sayyed ND, Lee YJ, Jeon HY, Kim EB, Hong SH, Cho S, Kim M, Ha KS.

(9) Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophagesCytokineApril 1, 2020Sestito C, Brevé JJP, Bol JGJM, Wilhelmus MMM, Drukarch B, van Dam AM.

(10) The vicious cycle between transglutaminase 2 and reactive oxygen species in hyperglycemic memory-induced endothelial dysfunctionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyNovember 1, 2019Lee JY, Lee YJ, Jeon HY, Han ET, Park WS, Hong SH, Kim YM, Ha KS.

(11) The GTP binding activity of transglutaminase 2 promotes bone metastasis of breast cancer cells by downregulating microRNA-205American journal of cancer researchJanuary 1, 2019Seo S, Moon Y, Choi J, Yoon S, Jung KH, Cheon J, Kim W, Kim D, Lee CH, Kim SW, et al.

(12) Transglutaminase is a mesothelioma cancer stem cell survival protein that is required for tumor formationOncotargetOctober 2, 2018Adhikary G, Grun D, Alexander HR, Friedberg JS, Xu W, Keillor JW, Kandasamy S, Eckert RL.(NA934V) were obtained from GE Healthcare (Buckinghamshire, UK) and used at 1:5000 dilution. TG2- (sc-37514) and control-siRNA (sc37007) and anti-Oct-4 (sc-9081) were purchased from Santa Cruz (Dallas, TX). Matrigel

(13) Arachidonic acid suppresses hepatic cell growth through ROS-mediated activation of transglutaminaseFEBS open bioOctober 1, 2018Qin XY, Lu J, Cai M, Kojima S.

(14) Tissue transglutaminase expression is necessary for adhesion, metastatic potential and cancer stemness of renal cell carcinomaCell adhesion & migrationMarch 4, 2018Bagatur Y, Ilter Akulke AZ, Bihorac A, Erdem M, Telci D.

(15) Transglutaminase 2 Regulates Self-renewal and Stem Cell Marker of Human Colorectal Cancer Stem CellsAnticancer researchFebruary 1, 2018Kang S, Oh SC, Min BW, Lee DH.

(16) Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?Journal of neuroinflammationDecember 21, 2017Sestito C, Brevé JJP, van Eggermond MCJA, Killestein J, Teunissen CE, van Rossum J, Wilhelmus MMM, Drukarch B, van den Elsen PJ, van Dam AM.

(17) Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor FormationCancer researchDecember 15, 2016Fisher ML, Kerr C, Adhikary G, Grun D, Xu W, Keillor JW, Eckert RL.(Buckinghamshire, UK). Alexaflour 555 (A21424) and Alexaflour 488 (A11034) were from Invitrogen. TG2- (sc-37514), p63- (sc-36161), FAK- (sc-29310), integrin α6- (sc-43129), integrin β4- (sc-35678) and control-siRNA

(18) Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transitionOncotargetAugust 21, 2015Fisher ML, Adhikary G, Xu W, Kerr C, Keillor JW, Eckert RL.Invitrogen. DAPI (D9542) was purchased from Sigma. NC9 synthesis was previously described [27, 28]. TG2- (sc-37514) and control-siRNA (sc-37007) were purchased from Santa Cruz (Dallas, TX). TG2, NFκB signaling and

(19) Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell SurvivalMolecular cancer research : MCRJuly 1, 2015Fisher ML, Keillor JW, Xu W, Eckert RL, Kerr C.obtained from GE Healthcare (Buckinghamshire, UK). Production of NC9 was described previously (16). TG2- (sc-37514) and control-siRNA (sc-37007) were purchased from Santa Cruz (Dallas, TX). Anti-TG1 (SC-166467) and

(20) Transglutaminase 2 reprogramming of glucose metabolism in mammary epithelial cells via activation of inflammatory signaling pathwaysInternational journal of cancerJune 15, 2014Kumar S, Donti TR, Agnihotri N, Mehta K.

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TGase2 siRNA (h)

TGase2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TGase2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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