R2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemR2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36338
Gene Nameribonucleotide reductase M2
Quantity10 µM
Specieshuman
NCBI Full Gene Nameribonucleotide reductase regulatory subunit M2
NCBI Gene AliasesC2orf48, R2, RR2, RR2M
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumorCancer LettersAugust 1, 2024Zeta Chow, Jeremy Johnson, Aman Chauhan, Jong Cheol Jeong, Jennifer T. Castle, Tadahide Izumi, Heidi Weiss, Courtney M. Townsend, Jörg Schrader, Lowell Anthony, et al.transfection. RRM1, RRM2 and p53R2 subunit siRNA were purchased from Santa Cruz: siRNA RRM1 (SC-37640), siRNA RRM2 (SC-36338), and siRNA p53R2 (SC-36158); transfection reagent was purchased from Invitrogen: Lipofectamine™ RNAiMax

(2) RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signalingOncology lettersApril 1, 2020Zhuang S, Li L, Zang Y, Li G, Wang F.participants. The obtained samples were preserved in liquid nitrogen and stored at ‑80˚C until processing. no. sc‑36338) and scrambled siRNA (cat. no. sc‑37007; used as a negative control; si‑NC) were applied and purchased from

(3) Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β‑catenin signaling pathwayMolecular medicine reportsSeptember 1, 2019Liu X, Peng J, Zhou Y, Xie B, Wang J.without antibiotics at 37°C for 24 h. Cells were transfected with RRM2 siRNA (siRRM2; 10 µM; cat. no. sc-36338; Santa Cruz Biotechnology, Inc.) using Lipofectamine® 3000 (Invitrogen, Thermo Fisher Scientific, Inc.).

(4) Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non-Small-Cell Lung CancerThe American journal of pathologyJanuary 1, 2018Zhang K, Keymeulen S, Nelson R, Tong TR, Yuan YC, Yun X, Liu Z, Lopez J, Raz DJ, Kim JY.

(5) Diagnostic Microdosing Approach to Study Gemcitabine ResistanceChemical research in toxicologyNovember 21, 2016Scharadin TM, Zhang H, Zimmermann M, Wang S, Malfatti MA, Cimino GD, Turteltaub K, de Vere White R, Pan CX, Henderson PT.

(6) Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 proteinBiochemical pharmacologyMarch 1, 2016Liu X, Xu Z, Hou C, Wang M, Chen X, Lin Q, Song R, Lou M, Zhu L, Qiu Y, et al.

(7) E2F1 promote the aggressiveness of human colorectal cancer by activating the ribonucleotide reductase small subunit M2Biochemical and biophysical research communicationsAugust 21, 2015Fang Z, Gong C, Liu H, Zhang X, Mei L, Song M, Qiu L, Luo S, Zhu Z, Zhang R, et al.

(8) Reciprocal regulation of autophagy and dNTP pools in human cancer cellsAutophagyJuly 1, 2014Chen W, Zhang L, Zhang K, Zhou B, Kuo ML, Hu S, Chen L, Tang M, Chen YR, Yang L, et al.(Sigma, A5441) and BECN1 (BD Biosciences, 612113). Silencing of RRM2 by siRNA The human RRM2 siRNA (sc-36338) and control siRNA (sc-36338) were purchased from Santa Cruz Biotechnology. A total of 2 × 105 cells

(9) p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrestMolecular cancer therapeuticsFebruary 1, 2011Zhang K, Wu J, Wu X, Wang X, Wang Y, Zhou N, Kuo ML, Liu X, Zhou B, Chang L, et al.and PD98059 were purchased from Sigma-Aldrich (St. Louis, MO). The human p53R2 gene specific siRNA (sc-36338) and scramble siRNA were purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). Addgene plasmid

(10) Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesisMolecular cancerFebruary 28, 2009Zhang K, Hu S, Wu J, Chen L, Lu J, Wang X, Liu X, Zhou B, Yen Y.or folds change to control sample. RRM2 siRNA Knockdown assay The human RRM2 gene specific siRNA (sc-36338) and scramble siRNA were purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). 5 × 105/well

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R2 siRNA (h)

R2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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R2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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