RUNX2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRUNX2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37145
Gene Namerunt related transcription factor 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameRUNX family transcription factor 2
NCBI Gene AliasesAML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) RUNX2 enhances vascular remodeling to promote endothelial proliferation in acute liver injuryInt J Biol SciMarch 28, 2026Jong-Min Lee, Yoon-Su Ha, Seung-Jun Lee, Hyun-Yi Kim, Anish Ashok Adpaikar, Eun-Jung Kim, Keishi Otsu, Xiangguo Che, Dai Hoon Han, Young Her, et al.in DMEM at 37 °C in a humidified atmosphere with 5% CO2. HUVECs were transfected with RUNX2 siRNA (SC-37145, Santa Cruz Biotechnology, Inc., USA), CITED2 siRNA (SC-35959, Santa Cruz Biotechnology, Inc.), and

(2) Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiationPharmacological ResearchNovember 1, 2025Yaqi Zhou, Dingwei Zhao, Qian Ma, Sujin Lee, Kangsan Roh, Yongfeng Cai, Jiean Xu, Qiuhua Yang, Qingen Da, Zhiping Liu, et al.nM siRNAs targeting human ADORA2A (siADORA2A, sc-39850, Santa Cruz Biotechnology, TX, USA; siRUNX2, sc-37145, Santa Cruz Biotechnology, TX, USA; siCREB1, sc-29281, Santa Cruz Biotechnology, TX, USA) or non-targeting

(3) RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transitionNatureApril 1, 2025Fang Y, Chung SSW, Xu L, Xue C, Liu X, Jiang D, Li R, Korogi Y, Yuan K, Saqi A, et al.mycoplasma contamination. Human normal lung fibroblasts were transfected with RUNX2 siRNA (Santa Cruz, sc-37145) or a non-targeting control siRNA (Santa Cruz, sc-37007) using Lipofectamine RNAiMAX Reagent (Thermofisher,

(4) Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cellsStem cell research & therapyJune 3, 2020Lee HM, Seo SR, Kim J, Kim MK, Seo H, Kim KS, Jang YJ, Ryu CJ.

(5) The significance of Runx2 mediating alcohol-induced Brf1 expression and RNA Pol III gene transcriptionChemico-biological interactionsMay 25, 2020Hong Z, Fang Z, Lei J, Shi G, Zhang Y, He Z, Li B W, Zhong S.

(6) RUNX2 interacts with BRG1 to target CD44 for promoting invasion and migration of colorectal cancer cellsCancer cell internationalJanuary 1, 2020Yan X, Han D, Chen Z, Han C, Dong W, Han L, Zou L, Zhang J, Liu Y, Chai J.Life Technologies, USA). siRNA specific for human RUNX2 was obtained from Santa Cruz Biotechnology (sc-37145). RUNX2 siRNA (h) is a pool of 3 different siRNA duplexes, A-sense: CCAUAACCGUCUUCACAAAtt, UUUGUGAAGACGGUUAUGGtt

(7) Acquisition of tumorigenic potential and therapeutic resistance in CD133+ subpopulation of prostate cancer cells exhibiting stem-cell like characteristicsCancer lettersAugust 28, 2018Kanwal R, Shukla S, Walker E, Gupta S.

(8) Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosisFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2018Mümmler C, Burgy O, Hermann S, Mutze K, Günther A, Königshoff M.

(9) MicroRNA-221 is involved in the regulation of osteoporosis through regulates RUNX2 protein expression and osteoblast differentiationAmerican journal of translational researchJanuary 1, 2017Zhang Y, Gao Y, Cai L, Li F, Lou Y, Xu N, Kang Y, Yang H.

(10) miR-203 inhibits the traumatic heterotopic ossification by targeting Runx2Cell death & diseaseOctober 27, 2016Tu B, Liu S, Yu B, Zhu J, Ruan H, Tang T, Fan C.

(11) RUNX2 controls human IPO8 basal transcription in Saos-2 cellsMolecular medicine reportsAugust 1, 2016Xiong J, Hu Z, Wang T, Xu X, Liu J, Wu P, Che X, Li W.

(12) NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistanceCell death & diseaseJune 23, 2016Emma MR, Iovanna JL, Bachvarov D, Puleio R, Loria GR, Augello G, Candido S, Libra M, Gulino A, Cancila V, et al.from Santa Cruz: siNUPR1 #2 (sc-40792); siRELB #1 (sc-36402); siIER3 #1 (sc-43859); and siRUNX2 #1 (sc-37145). Negative control siRNA (siNC) was purchased from QIAGEN (1027281). Extraction of cellular RNA and

(13) LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulationAtherosclerosisFebruary 1, 2016Afonso P, Auclair M, Boccara F, Vantyghem MC, Katlama C, Capeau J, Vigouroux C, Caron-Debarle M.

(14) Periodontal ligament stem cells modulate root resorption of human primary teeth via Runx2 regulating RANKL/OPG systemStem cells and developmentOctober 15, 2014Li B, Zhang Y, Wang Q, Dong Z, Shang L, Wu L, Wang X, Jin Y.

(15) A feedback loop between RUNX2 and the E3 ligase SMURF1 in regulation of differentiation of human dental pulp stem cellsJ EndodOctober 1, 2014Yang F, Xu N, Li D, Guan L, He Y, Zhang Y, Lu Q, Zhang X.

(16) Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticumOrphanet journal of rare diseasesApril 29, 2014Hosen MJ, Coucke PJ, Le Saux O, De Paepe A, Vanakker OM.were seeded in 6 well plates. After 24 hrs. cells were transfected with 6 μl (2 μM) of RUNX2 siRNA (sc-37145, sc-36868, sc-29528, Santa Cruz Biotechnology, Inc, Europe) or scrambled RNA (sc37007, Santa Cruz Biotechnology, Inc

(17) Low-intensity pulsed ultrasound accelerates tooth movement via activation of the BMP-2 signaling pathwayPloS oneJanuary 1, 2013Xue H, Zheng J, Cui Z, Bai X, Li G, Zhang C, He S, Li W, Lajud SA, Duan Y, et al.Recombinant human HGF was purchased from PeproTech (Rocky Hill, NJ). The small interfering RNAs against Runx2 (sc-37145), and a control siRNA (sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA). FBS/Media

(18) Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistanceBritish journal of cancerNovember 6, 2012Browne G, Nesbitt H, Ming L, Stein GS, Lian JB, McKeown SR, Worthington J.

(19) Runx2-mediated bcl-2 gene expression contributes to nitric oxide protection against hydrogen peroxide-induced osteoblast apoptosisJournal of cellular biochemistryDecember 1, 2009Ho WP, Chan WP, Hsieh MS, Chen RM.

(20) Modulating hedgehog signaling can attenuate the severity of osteoarthritisNature medicineDecember 1, 2009Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L, Hsu C, Ali SA, Alman BA.

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RUNX2 siRNA (h)

RUNX2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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RUNX2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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