PKAα cat siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPKAα cat siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36240
Gene Nameprotein kinase, cAMP-dependent, catalytic, alpha
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein kinase cAMP-activated catalytic subunit alpha
NCBI Gene AliasesCAFD1, PKACA, PPNAD4
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Globo H ceramide confers chemoresistance and poor prognosis to advanced gallbladder cancer via A2AR/cAMP/PKA pathwayTheranosticsFebruary 26, 2026Tsai-Hsien Hung, Jung-Tung Hung, Wen-Kuan Huang, Yenlin Huang, Chiao-En Wu, Jing-Yan Cheng, Chien-Wei Lee, John Yu, Yi-Chia Wu, Chun-Nan Yeh, et al.SNU308, TGBC24, and GBC01 cells were transfected with small interfering RNAs (siRNAs) targeting PRKACA (sc-36240, Santa Cruz Biotechnology, USA), A2AR (sc-39850, Santa Cruz Biotechnology, USA) or ABCG2 (sc-41151,

(2) Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesisJournal of CancerJanuary 1, 2023Jia Y, Li HY, Wang J, Chen X, Lou L, Wei YY, Wang Y, Mo SJ.were synthesized by GenePharma (Shanghai, China), respectively. P53 shRNA (#sc-29435-V), PKA siRNA (#sc-36240) and non-specific control siRNA (#sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz,

(3) TGFβ-Induced Lung Cancer Cell Migration Is NR4A1-DependentMolecular cancer research : MCRDecember 1, 2018Hedrick E, Mohankumar K, Safe S.Santa Cruz Biotechnology: c-jun siRNA(h): sc29223; c-jun siRNA(h2): sc-44201 SRF siRNA: sc-36563; PKACα siRNA: sc-36240. PKA activity assay. A549 lung cancer cells (3.0 × 105 per well) were seeded in Dulbecco’s modified

(4) Membrane and nuclear estrogen receptor α collaborate to suppress adipogenesis but not triglyceride contentFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2016Pedram A, Razandi M, Blumberg B, Levin ER.

(5) Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cellsOncotargetDecember 15, 2015Kim HIe, Lee HS, Kim TH, Lee JS, Lee ST, Lee SJ.c-Src, and α3 integrin in A549 cells A549 cells were transfected with various siRNAs [PKAα cat siRNA (sc-36240), 80 nM; α3-integrin siRNA (sc-35684), 50 nM; c-Src siRNA (sc-29228), 50 nM; control siRNA (sc-37007),

(6) CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axisFree radical biology & medicineDecember 1, 2015Hwang S, Lee HJ, Kim G, Won KJ, Park YS, Jo I.

(7) Constitutively Active Signaling by the G Protein βγ-Subunit Mediates Intrinsically Increased Phosphodiesterase-4 Activity in Human Asthmatic Airway Smooth Muscle CellsPLOS ONEMarch 5, 2015Aihua Hu, Barry L. Diener, Maureen B. Josephson, Michael M. Grunstein(Ambion; ID: 18059, 18147, 135857), or the PKAα catalytic subunit (Santa Cruz Biotechnology; Pool ID: sc-36240), as well as a non-targeted (scrambled) siRNA duplex serving as a negative control. As previously described

(8) Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathwayAutophagyDecember 1, 2013Chen ML, Yi L, Jin X, Liang XY, Zhou Y, Zhang T, Xie Q, Zhou X, Chang H, Fu YJ, et al.

(9) Differential PKA activation and AKAP association determines cell fate in cancer cellsJournal of molecular signalingOctober 1, 2013Hedrick ED, Agarwal E, Leiphrakpam PD, Haferbier KL, Brattain MG, Chowdhury S.IP based on antibody titration and immunoblotted from survivin. RNA interference studies PKAα Cat (sc-36240), Praja2 (sc-91836) and AKAP149 (sc-136355) siRNAs and Smad3 shRNA (sc-77326-SH) were obtained from

(10) cAMP-dependent protein kinase is essential for hypoxia-mediated epithelial-mesenchymal transition, migration, and invasion in lung cancer cellsCellular signallingDecember 1, 2012Shaikh D, Zhou Q, Chen T, Ibe JC, Raj JU, Zhou G.

(11) Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10FEBS lettersJuly 30, 2012Gu J, Shi J, Wu S, Jin N, Qian W, Zhou J, Iqbal IG, Iqbal K, Gong CX, Liu F.

(12) Cell contact-dependent functional selectivity of β2-adrenergic receptor ligands in stimulating cAMP accumulation and extracellular signal-regulated kinase phosphorylationThe Journal of biological chemistryFebruary 24, 2012Kaya AI, Onaran HO, Özcan G, Ambrosio C, Costa T, Balli S, Ugur Ö.

(13) Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell deathThe Journal of biological chemistrySeptember 2, 2011Chowdhury S, Howell GM, Teggart CA, Chowdhury A, Person JJ, Bowers DM, Brattain MG.

(14) Identification of a novel TGFβ/PKA signaling transduceome in mediating control of cell survival and metastasis in colon cancerPloS oneMay 3, 2011Chowdhury S, Howell GM, Rajput A, Teggart CA, Brattain LE, Weber HR, Chowdhury A, Brattain MG.

(15) Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 inductionAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2008Hu A, Nino G, Grunstein JS, Fatma S, Grunstein MM.

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PKAα cat siRNA (h)

PKAα cat siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PKAα cat siRNA (h) from Santa Cruz Biotechnology, Inc.

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