Akt1/2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemAkt1/2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43609
Gene Namev-akt murine thymoma viral oncogene homolog 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameAKT serine/threonine kinase 2, AKT serine/threonine kinase 1
NCBI Gene AliasesPKB, RAC, PRKBB, PKB-ALPHA, PRKBA, AKT, HIHGHH, RAC-ALPHA, RAC-BETA, PKBBETA, PKBB
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Daunorubicin induces GLI1‑dependent apoptosis in colorectal cancer cell linesInternational journal of oncologyJune 1, 2024Kim BR, Kim DY, Tran NL, Kim BG, Lee SI, Kang SH, Min BY, Hur W, Oh SC.films. Transfection Con siRNA (cat. no. sc-37007), GLI1 siRNA (cat. no. sc-37911), AKT siRNA (cat. no. sc-43609), ERK siRNA (cat. no. sc-29307, sc-35335), PCAF siRNA (cat. no. sc-36198) and β-TrCP siRNA (cat. no.

(2) Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem CellsInternational journal of molecular sciencesFebruary 20, 2022Simbulan-Rosenthal CM, Haribabu Y, Vakili S, Kuo LW, Clark H, Dougherty R, Alobaidi R, Carney B, Sykora P, Rosenthal DS.

(3) Identification of Gαi3 as a promising target for osteosarcoma treatmentInternational journal of biological sciencesJanuary 1, 2022Bian ZJ, Shan HJ, Zhu YR, Shi C, Chen MB, Huang YM, Wang XD, Zhou XZ, Cao C.

(4) Chronic stress promotes glioma cell proliferation via the PI3K/Akt signaling pathwayOncology reportsSeptember 1, 2021Zhang ZQ, Wang X, Xue BH, Zhao Y, Xie F, Wang SD, Xue C, Wang Y, Zhang YS, Qian LJ.negative control and siRNA group. For siRNA against Akt, the product Akt1/2 siRNA (h) (product no. sc-43609) was used, purchased from Santa Cruz Biotechnology, Inc. siRNA or siRNA negative control was diluted

(5) RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in colorectal cancer cellsJournal of ethnopharmacologyFebruary 10, 2021Wang J, Wang J, Li L, Feng L, Wang YR, Wang Z, Tan NH.

(6) PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomasOncogenesisJanuary 19, 2021Yoon C, Lu J, Yi BC, Chang KK, Simon MC, Ryeom S, Yoon SS.

(7) AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5Journal of immunology (Baltimore, Md. : 1950)October 15, 2020Zhao W, Shi CS, Harrison K, Hwang IY, Nabar NR, Wang M, Kehrl JH.

(8) Adropin regulates hepatic glucose production via PP2A/AMPK pathway in insulin-resistant hepatocytesFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2020Chen X, Chen S, Shen T, Yang W, Chen Q, Zhang P, You Y, Sun X, Xu H, Tang Y, et al.

(9) Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinomaJournal of experimental & clinical cancer research : CRMay 14, 2020Li M, Gao F, Yu X, Zhao Q, Zhou L, Liu W, Li W.

(10) Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cellsThe Journal of clinical investigationMay 1, 2020Palrasu M, Zaika E, El-Rifai W, Garcia-Buitrago M, Piazuelo MB, Wilson KT, Peek RM Jr, Zaika AI.Technologies. PI3K (catalog sc-37269), XIAP (catalog sc-37508), Cbl-b (catalog sc-29950), and Akt (catalog sc-43609) siRNA were purchased from Santa Cruz Biotechnology. Control (catalog AM4636) and XIAP (catalog AM51331) siRNA

(11) Disulfide Cleavage in a Dimeric Epipolythiodioxopiperazine Natural Product Diminishes Its Apoptosis-Inducing Effect but Enhances Autophagy in Tumor CellsJournal of natural productsMarch 27, 2020Li E, Hou B, Gao Q, Xu Y, Zhang C, Liu X, Jiang X, Che Y.

(12) Hepatitis B virus upregulates cellular inhibitor of apoptosis protein 2 expression via the PI3K/AKT/NF-κB signaling pathway in liver cancerOncology lettersMarch 1, 2020Lian J, Zou Y, Huang L, Cheng H, Huang K, Zeng J, Chen L.RNA (siRNA)‑mediated knockdown of p65 or AKT, siRNA targeting p65 (cat. no. sc‑29410), AKT (cat. no. sc‑43609) or control siRNA (cat. no. sc‑37007) at a final concentration of 100 nM was introduced into cells using

(13) MicroRNA-31/184 is involved in transforming growth factor-β-induced apoptosis in A549 human alveolar adenocarcinoma cellsLife sciencesFebruary 1, 2020Wang CJ, Li BB, Tan YJ, Zhang GM, Cheng GL, Ren YS.

(14) Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic GlycolysisOncoTargets and therapyJanuary 1, 2020Liu W, Yu X, Zhou L, Li J, Li M, Li W, Gao F.transfected with HK2 sgRNA and selected by 1μg/mL puromycin for three weeks. The Akt1/2 siRNA pool (sc-43609) and siCtrl (sc-37007) were purchased from Santa Cruz Biotechnology (Dallas, TX). MTS Assays The CellTiter

(15) Mcl-1 Interacts with Akt to Promote Lung Cancer ProgressionCancer researchDecember 15, 2019Chen G, Park D, Magis AT, Behera M, Ramalingam SS, Owonikoko TK, Sica GL, Ye K, Zhang C, Chen Z, et al.(sc-47778), anti-Bax (sc-493), anti-HA (sc-7392) and anti-GFP (sc-9996) antibodies as well as Akt1/2 siRNA (sc-43609) were purchased from Santa Cruz Biotechnology (Dallas, Texas). Anti-pAkt S473 (#9271), anti-pAkt T308

(16) Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancerAgingSeptember 23, 2019Shan L, Liu W, Zhan Y.37°C in a humid incubator containing 5% CO2 and 95% air. Control siRNA (sc-37007) and Akt1/2 siRNA (sc-43609) were obtained from Santa Cruz Biotechnology, Inc. (Dallas, Texas, USA). The selective FGFR inhibitor

(17) Induction of tolerogenic dendritic cells by activated TGF-β/Akt/Smad2 signaling in RIG-I-deficient stemness-high human liver cancer cellsBMC cancerMay 14, 2019Zhong M, Zhong C, Cui W, Wang G, Zheng G, Li L, Zhang J, Ren R, Gao H, Wang T, et al.

(18) Induction of HSP27 and HSP70 by constitutive overexpression of Redd1 confers resistance of lung cancer cells to ionizing radiationOncology reportsMay 1, 2019Jin HO, Hong SE, Kim JY, Kim MR, Chang YH, Hong YJ, Lee JK, Park IC.stage IV lung cancer samples. siRNAs and transfections. Redd1 (cat. no. sc‑45806), AKT1/2 (cat. no. sc‑43609), Rictor (cat. no. sc‑61478) and control (cat. no. sc‑37007) siRNAs were purchased from Santa Cruz Biotechnology, Inc

(19) Distinct role of 4E-BP1 and S6K1 in regulating autophagy and hepatitis B virus (HBV) replicationLife sciencesMarch 1, 2019Gao Q, Hou B, Yang H, Jiang X.

(20) Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagyTheranosticsJanuary 1, 2019Zhang X, Qi Z, Yin H, Yang G.China) according to the manufacturer's instructions. SiRNAs for ERK1/2 (sc-29307/ sc-35335) and AKT1/2 (sc-43609) and a control siRNA (sc-37007) were purchased from Santa Cruz Biotech and transfected into SKOV3T/V12

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Akt1/2 siRNA (h)

Akt1/2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Akt1/2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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