IRE1α siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIRE1α siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-40705
Gene Nameendoplasmic reticulum to nucleus signaling 1
Quantity10 µM
Specieshuman
NCBI Full Gene Nameendoplasmic reticulum to nucleus signaling 1
NCBI Gene AliasesIRE1, IRE1P, IRE1a, hIRE1p
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A novel role of liquid plasma (LP) induced RONS triggers the endoplasmic reticulum stress response and is associated with GSDME-mediated pyroptosis in anaplastic thyroid cancerCell communication and signaling : CCSOctober 2, 2025Ji EJ, Yeou SH, Kang SU, Kim CH.DFNA5/GSDME, IRE1α siRNA was purchased from Santa Cruz Biotechnology (DFNA5/GSDME; sc-77136, IRE1α; sc-40705, allas, TX, USA). Annexin V and propidium iodide staining Apoptoic cell death was detected using the

(2) Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axisJournal of Advanced ResearchSeptember 1, 2025Xige Zhang, Yazheng Wang, Jinjin Wang, Yang Zhang, Rui Li, Xiaoyu Wang, Xiaotong Ge, Qingyuan Ye, Jiyun Ji, Dongdong Fei, et al.transfected with 50 nM PERK (Santa Cruz Biotechnology, sc-36213, CA, USA), IRE1α (Santa Cruz Biotechnology, sc-40705), and ATF6 small interfering RNA (siRNA) (Genechem, Shanghai, China), and those in the control group

(3) BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1iScienceDecember 22, 2022Hromas R, Srinivasan G, Yang M, Jaiswal A, Totterdale TA, Phillips L, Kirby A, Khodayari N, Brantley M, Williamson EA, et al.

(4) TXNIP Links Anticipatory Unfolded Protein Response to Estrogen Reprogramming Glucose Metabolism in Breast Cancer CellsEndocrinologyJanuary 1, 2022Wang Y, Chen S.

(5) PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cellsCell death & diseaseNovember 1, 2021Sheshadri N, Poria DK, Sharan S, Hu Y, Yan C, Koparde VN, Balamurugan K, Sterneck E.5′-rCrUrGrUrUrGrArArGrArGrGrUrCrGrGrCrGrATT-3′ siRNA pools for ATF6A/ATF6α (sc-37699), ERN1/IRE1α (sc-40705), EIF2AK3/PERK (sc-36213), NRF2 (sc-37030) and STAT3 (sc-29493) were purchased from Santa Cruz Biotechnology. RNA

(6) Endoplasmic reticulum stress/XBP1 promotes airway mucin secretion under the influence of neutrophil elastaseInternational journal of molecular medicineMay 1, 2021Xu X, Li Q, Li L, Zeng M, Zhou X, Cheng Z.

(7) Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in GliomaInternational journal of molecular sciencesApril 11, 2021Chang CY, Pan PH, Wu CC, Liao SL, Chen WY, Kuan YH, Wang WY, Chen CJ.Minneapolis, MN, USA). 4.7. Small Interfering RNA (siRNA) Transfection The siRNA against human IRE1 (sc-40705), Noxa (sc-37305), and control siRNA (sc37007; Santa Cruz Biotechnology, Santa Cruz, CA, USA) were delivered

(8) Nuclear factor-kappa B signaling in endometriotic stromal cells is not inhibited by progesterone owing to an aberrant endoplasmic reticulum stress response: a possible role for an altered inflammatory process in endometriosisMolecular human reproductionFebruary 5, 2021Choi J, Jo M, Lee E, Lee DY, Choi D.

(9) Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine FunctionInternational journal of molecular sciencesJanuary 12, 2021Fraichard C, Bonnet-Serrano F, Laguillier-Morizot C, Hebert-Schuster M, Lai-Kuen R, Sibiude J, Fournier T, Cohen M, Guibourdenche J.

(10) Synergistic antitumor effect of 5-fluorouracil and withaferin-A induces endoplasmic reticulum stress-mediated autophagy and apoptosis in colorectal cancer cellsAmerican journal of cancer researchJanuary 1, 2020Alnuqaydan AM, Rah B, Almutary AG, Chauhan SS.

(11) Dienogest regulates apoptosis, proliferation, and invasiveness of endometriotic cyst stromal cells via endoplasmic reticulum stress inductionMolecular human reproductionJanuary 1, 2020Choi J, Jo M, Lee E, Lee DY, Choi D.

(12) The fine-tuning of endoplasmic reticulum stress response and autophagy activation during trophoblast syncytializationCell death & diseaseSeptember 9, 2019Bastida-Ruiz D, Yart L, Wuillemin C, Ribaux P, Morris N, Epiney M, Martinez de Tejada B, Cohen M.

(13) Korean Red Ginseng Extract Increases Apoptosis by Activation of the Noxa Pathway in Colorectal CancerNutrientsAugust 29, 2019Jeong YA, Kim BR, Kim DY, Jeong S, Na YJ, Kim JL, Yun HK, Kim BG, Park SH, Jo MJ, et al.

(14) Dual effects of gossypol on human hepatocellular carcinoma via endoplasmic reticulum stress and autophagyThe international journal of biochemistry & cell biologyAugust 1, 2019Zhang G, Wang Z, Chen W, Cao Y, Wu J, Qiang G, Ji A, Wu J, Jiang C.

(15) Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liverBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJuly 1, 2019Jia B, Wang Y, Yu G, Cheng Y, Yang C, Cao F, He Y, Cao P, Meng X, Yu D.

(16) RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancerOncogeneMay 1, 2019Kim BR, Park SH, Jeong YA, Na YJ, Kim JL, Jo MJ, Jeong S, Yun HK, Oh SC, Lee DH.

(17) Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle sizeJournal of nanobiotechnologyFebruary 5, 2019Lee K, Lee J, Kwak M, Cho YL, Hwang B, Cho MJ, Lee NG, Park J, Lee SH, Park JG, et al.

(18) The TLR4-IRE1α pathway activation contributes to palmitate-elicited lipotoxicity in hepatocytesJournal of cellular and molecular medicineJuly 1, 2018Shen C, Ma W, Ding L, Li S, Dou X, Song Z.TLR4 siRNA (Thermo Fisher Scientific, AM16708) or human IRE1alpha siRNA (Santa Cruz Biotechnology, sc‐40705), using Lipofectamine 2000 according to the manufacturer's instructions. In the control group, cells

(19) Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1α/NF-κB signaling pathwayFood & functionApril 25, 2018Chen J, Zhang M, Zhu M, Gu J, Song J, Cui L, Liu D, Ning Q, Jia X, Feng L.

(20) 3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cellsOncotargetAugust 29, 2017Go DH, Lee YG, Lee DH, Kim JA, Jo IH, Han YS, Jo YH, Kim KY, Seo YK, Moon JH, et al.

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IRE1α siRNA (h)

IRE1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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IRE1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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