HSC 70 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHSC 70 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29349
Gene Nameheat shock 70kDa protein 8
Quantity10 µM
Specieshuman
NCBI Full Gene Nameheat shock protein family A (Hsp70) member 8
NCBI Gene AliasesHEL-33, HEL-S-72p, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP-1, LAP1, NIP71
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Senecavirus a VP2 protein orchestrates PRDX1 degradation through dual autophagy pathways: macroautophagy and chaperone-mediated autophagyAutophagyJanuary 2, 2026Zhaoyang Li, Xiaoyu Yang, Jingyu Mao, Penghui Zeng, Yuxiang Qi, Yongyan Shi, Jinshuo Guo, Jianwei Zhou, Dedong Wang, Jue Liu, et al.or dimethyl sulfoxide (DMSO) before use. Small interfering RNAs (siRNAs) targeting HSPA8 (siHSPA8, sc-29349) and PRDX1 (siPRDX1, sc-36177) were purchased from Santa Cruz Biotechnology. Plasmid construction All

(2) The E3 ubiquitin ligase STUB1 inhibits Senecavirus A replication by mediating VP1 ubiquitination and proteasomal degradationJ VirolOctober 23, 2025Penghui Zeng, Jingyu Mao, Jinshuo Guo, Xiaoyu Yang, Yongyan Shi, Xiaoyu Wang, Jiangwei Song, Jianwei Zhou, Lei Hou, Jue LiuSTUB1 and HSP70 genes were designed and synthesized by GenePharma. The siRNA targeting HSC70 (siHSC70, sc-29349) was purchased from Santa Cruz. Cells were transfected with siRNA using Lipofectamine RNAiMAX (13778;

(3) The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKK β and increasing the stability of I κ B αEmerging Microbes & InfectionsDecember 31, 2024Tao Wang, Rui Luo, Jing Zhang, Jing Lan, Zhanhao Lu, Huanjie Zhai, Lian-Feng Li, Yuan Sun, Hua-Ji Qiuand synthesized by GenePharma (Shanghai, China) (Table S1). The HSC70-specific siRNAs (catalog no. sc-29349) were purchased from Santa Cruz Biotechnology. For siRNA transfection, 100 pmol of the siRNAs were transfected

(4) PIP5Kγ Mediates PI(4,5)P2/Merlin/LATS1 Signaling Activation and Interplays with Hsc70 in Hippo-YAP Pathway RegulationInternational journal of molecular sciencesSeptember 30, 2023Le DDT, Le TPH, Lee SY.mixed with Lipofectamine 2000 in Opti-MEM I. For PIP5Kγ and Hsc70 knockdown, their siRNAs (sc-39137 and sc-29349, respectively, Santa Cruz Biotechnology) mixed with Lipofectamine RNAiMAX in Opti-MEM I were added to

(5) HSC70 and HSP90 chaperones perform complementary roles in translocation of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosolThe Journal of biological chemistryAugust 9, 2019Burress H, Kellner A, Guyette J, Tatulian SA, Teter K.

(6) Hsc70 Interacts with β4GalT5 to Regulate the Growth of GliomasNeuromolecular medicineMarch 1, 2019Sun G, Cao Y, Dai X, Li M, Guo J.

(7) HSP70 Copurifies with Zika Virus ParticlesVirologySeptember 1, 2018Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW.

(8) Hepatitis C Virus NS5A Protein Promotes the Lysosomal Degradation of Hepatocyte Nuclear Factor 1α via Chaperone-Mediated AutophagyJournal of virologyJuly 1, 2018Matsui C, Deng L, Minami N, Abe T, Koike K, Shoji I.follows: siLAMP2A, 5=-CUGCAAU CUGAUUGAUUAUU-3=, and siScrLAMP2A, 5=-GUGACUUUACAUCAUUUAGU-3=. HSC70 siRNA (sc-29349; Santa Cruz Biotechnologies) was used for knockdown of HSC70 mRNA. The siScrHSC70 target sequence was

(9) Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated MicrogliaFrontiers in molecular neuroscienceJanuary 1, 2018Liu L, An D, Xu J, Shao B, Li X, Shi J.

(10) The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycleVirologyApril 1, 2014Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW.

(11) Proteomic analysis of an imatinib-resistant K562 cell line highlights opposing roles of heat shock cognate 70 and heat shock 70 proteins in resistanceProteomicsJune 1, 2008Pocaly M, Lagarde V, Etienne G, Dupouy M, Lapaillerie D, Claverol S, Vilain S, Bonneu M, Turcq B, Mahon FX, et al.

(12) Hsp70/Hsc70 regulates the effect phosphorylation has on stabilizing ataxin-1Journal of neurochemistrySeptember 1, 2007Jorgensen ND, Andresen JM, Pitt JE, Swenson MA, Zoghbi HY, Orr HT.

(13) Identification of Hsc70 as an influenza virus matrix protein (M1) binding factor involved in the virus life cycleFEBS lettersOctober 16, 2006Watanabe K, Fuse T, Asano I, Tsukahara F, Maru Y, Nagata K, Kitazato K, Kobayashi N.

(14) Rituximab enhances radiation-triggered apoptosis in non-Hodgkin's lymphoma cells via caspase-dependent and - independent mechanismsJournal of radiation researchJune 1, 2006Skvortsova I, Skvortsov S, Popper BA, Haidenberger A, Saurer M, Gunkel AR, Zwierzina H, Lukas P.

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HSC 70 siRNA (h)

HSC 70 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HSC 70 siRNA (h) from Santa Cruz Biotechnology, Inc.

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