LDH-A siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemLDH-A siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43893
Quantity10 µM
Specieshuman
NCBI Full Gene Namelactate dehydrogenase A
NCBI Gene AliasesGSD11, HEL-S-133P, LDHM, PIG19
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertensionJournal of Translational MedicineAugust 5, 2024Daiqian Wu, Shuo Wang, Fengxian Wang, Qing Zhang, Zhen Zhang, Xingbing Lion mPASMCs under normoxic or hypoxic conditions, mPASMCs were transfected with LDHA siRNA (100 nM, sc-43893, Santa Cruz). To activate Akt signaling pathway, the Akt overexpression plasmid (Shanghai Genechem Co.,

(2) Influenza A induces lactate formation to inhibit type I IFN in primary human airway epitheliumiScienceNovember 19, 2021Thyrsted J, Storgaard J, Blay-Cadanet J, Heinz A, Thielke AL, Crotta S, de Paoli F, Olagnier D, Wack A, Hiller K, et al.for 24 hours. Cells were transfected using approx. 50 nM of human siLDHA (Santa Cruz Biotechnology, #sc-43893) or control siRNA (Santa Cruz Biotechnology, #sc-37007) diluted in DMEM (without serum and antibiotics).

(3) Lactate Dehydrogenase A or B Knockdown Reduces Lactate Production and Inhibits Breast Cancer Cell Motility in vitroFrontiers in pharmacologyJanuary 1, 2021Khajah MA, Khushaish S, Luqmani YA.reach 60–80% confluency before transfection using Lipofeactamine RNAiMAX reagent (Santa Cruz, Cat # sc-43893, sc-45899). The procedure was performed according to the manufacturer’s protocol. In brief, solution

(4) Lactate dehydrogenase A regulates autophagy and tamoxifen resistance in breast cancerBiochimica et biophysica acta. Molecular cell researchJune 1, 2019Das CK, Parekh A, Parida PK, Bhutia SK, Mandal M.

(5) Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cellsCell communication and signaling : CCSFebruary 11, 2019Wang F, Jia Y, Li M, Wang L, Shao J, Guo Q, Tan S, Ding H, Chen A, Zhang F, et al.

(6) FGF9-induced ovarian cancer cell invasion involves VEGF-A/VEGFR2 augmentation by virtue of ETS1 upregulation and metabolic reprogrammingJournal of cellular biochemistryNovember 1, 2018Bhattacharya R, Ray Chaudhuri S, Roy SS.

(7) The molecular mechanism and clinical significance of LDHA in HER2-mediated progression of gastric cancerAmerican journal of translational researchJanuary 1, 2018Zhu W, Ma L, Qian J, Xu J, Xu T, Pang L, Zhou H, Shu Y, Zhou J.

(8) Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progressionOncotargetNovember 10, 2015Chaube B, Malvi P, Singh SV, Mohammad N, Meena AS, Bhat MK.

(9) The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cellsMolecular cancer research : MCRApril 1, 2014Lee SO, Jin UH, Kang JH, Kim SB, Guthrie AS, Sreevalsan S, Lee JS, Safe S.

(10) Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinomaThe FEBS journalOctober 1, 2012Sheng SL, Liu JJ, Dai YH, Sun XG, Xiong XP, Huang G.

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LDH-A siRNA (h)

LDH-A siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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LDH-A siRNA (h) from Santa Cruz Biotechnology, Inc.

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