EPAS-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemEPAS-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35316
Gene Nameendothelial PAS domain protein 1
TypesiRNA/dsRNA
NCBI Gene AliasesECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73
NCBI Full Gene Nameendothelial PAS domain protein 1
Specieshuman
Quantity10 µM

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumorsOncogeneAugust 1, 2021Casillas AL, Chauhan SS, Toth RK, Sainz AG, Clements AN, Jensen CC, Langlais PR, Miranti CK, Cress AE, Warfel NA.(Lipofectamine 3000 Invitrogen). HIF-1α and siRNA was purchased from Santa Cruz Biotechnology (sc-44225 and sc-35316, respectively). PIM1 siRNA sequences were previously reported [58]. The following western blot antibodies

(2) PCAT-1 facilitates breast cancer progression via binding to RACK1 and enhancing oxygen-independent stability of HIF-1αMolecular therapy. Nucleic acidsJune 4, 2021Wang J, Chen X, Hu H, Yao M, Song Y, Yang A, Xu X, Zhang N, Gao J, Liu B.

(3) Hypoxia-inducible factor 2 alpha impairs human cytotrophoblast syncytialization: New insights into placental dysfunction and fetal growth restrictionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyNovember 1, 2020Colson A, Depoix CL, Baldin P, Hubinont C, Sonveaux P, Debiève F.

(4) Midkine Is a Potential Therapeutic Target of Tumorigenesis, Angiogenesis, and Metastasis in Non-Small Cell Lung CancerCancersAugust 24, 2020Shin DH, Jo JY, Kim SH, Choi M, Han C, Choi BK, Kim SS.OriGene Technologies, Inc. (Rockville, MD, USA). Small interfering (si)RNAS, siHIF-1α (sc-35561), siHIF-2α (sc-35316), and siMDK (sc-39711) were purchased from Santa Cruz Biotechnology, Inc. (Dallas, TX, USA). Antibodies

(5) Regulation of stanniocalcin-1 secretion by BeWo cells and first trimester human placental tissue from normal pregnancies and those at increased risk of developing preeclampsiaFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2020Abid N, Embola J, Tryfonos Z, Bercher J, Ashton SV, Khalil A, Thilaganathan B, Cartwright JE, Whitley GS.L with either 300nM of control siRNA‐A (Santa Cruz sc‐37007) or targeted si‐RNA EPAS‐1 (Santa Cruz sc‐35316) and transfected following the manufacturers' instructions using programs X‐005 as previously detailed.16

(6) Stabilization of Hypoxia-Inducible Factors and BNIP3 Promoter Methylation Contribute to Acquired Sorafenib Resistance in Human Hepatocarcinoma CellsCancersDecember 9, 2019Méndez-Blanco C, Fondevila F, Fernández-Palanca P, García-Palomo A, Pelt JV, Verslype C, González-Gallego J, Mauriz JL.Melbourne, VIC, Australia). 4.7. Gene Silencing Commercial siRNAs against EPAS-1 (i.e., HIF-2α) (sc-35316), HIF-1α (sc-35561), BNIP3 (sc-37451), and control siRNA encoding a non-targeting sequence (sc-36869)

(7) Extracellular adenosine promotes cell migration/invasion of Glioblastoma Stem-like Cells through A(3) Adenosine Receptor activation under hypoxiaCancer lettersApril 1, 2019Torres Á, Erices JI, Sanchez F, Ehrenfeld P, Turchi L, Virolle T, Uribe D, Niechi I, Spichiger C, Rocha JD, et al.

(8) Metallothionein 3 Is a Hypoxia-Upregulated Oncogene Enhancing Cell Invasion and Tumorigenesis in Human Bladder Carcinoma CellsInternational journal of molecular sciencesFebruary 23, 2019Tsui KH, Hou CP, Chang KS, Lin YH, Feng TH, Chen CC, Shin YS, Juang HH.

(9) COX-2/PGE2 Axis Regulates HIF2α Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib TreatmentClinical cancer research : an official journal of the American Association for Cancer ResearchJuly 1, 2018Dong XF, Liu TQ, Zhi XT, Zou J, Zhong JT, Li T, Mo XL, Zhou W, Guo WW, Liu X, et al.

(10) MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cellsToxicology in vitro : an international journal published in association with BIBRAApril 1, 2018Chen C, Yang Q, Wang D, Luo F, Liu X, Xue J, Yang P, Xu H, Lu J, Zhang A, et al.

(11) Hepatitis B virus upregulates GP73 expression by activating the HIF-2α signaling pathwayOncology lettersApril 1, 2018Yang SL, Zeng C, Fang X, He QJ, Liu LP, Bao SY, Pan X, Xiong ZF.purchased from Shanghai GeneChem Co., Ltd. (Shanghai, China). HIF‑2 α small interfering (si)RNA (cat. no. sc‑35316) and negative control siRNA (cat. no. sc‑37007) were purchased from Santa Cruz Biotechnology, Inc. HepG2 cells

(12) miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell MaturationFrontiers in physiologyJanuary 1, 2018Song N, Zhang T, Xu X, Lu Z, Yu X, Fang Y, Hu J, Jia P, Teng J, Ding X."Santa Cruz Biotechnology, Inc. (TX, USA)",sc-44225 Human HIF-2α (EPAS-1) siRNAs,"Santa Cruz Biotechnology, Inc. (TX, USA)",sc-35316 Human scramble siRNAs,"Santa Cruz Biotechnology, Inc. (TX, USA)",sc-37007 Antibody against GAPDH,"Santa Cruz Biotechnology, Inc

(13) VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1The Journal of cell biologyMarch 6, 2017Labrousse-Arias D, Martínez-Alonso E, Corral-Escariz M, Bienes-Martínez R, Berridy J, Serrano-Oviedo L, Conde E, García-Bermejo ML, Giménez-Bachs JM, Salinas-Sánchez AS, et al.

(14) Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxiaNucleic acids researchNovember 2, 2016Roche O, Deguiz ML, Tiana M, Galiana-Ribote C, Martinez-Alcazar D, Rey-Serra C, Ranz-Ribeiro B, Casitas R, Galera R, Fernández-Navarro I, et al.and western blot analyses. We used commercial siRNAs, HIF1A siRNA (Santa Cruz, sc-44225), EPAS1 siRNA (Santa Cruz sc-35316) and siRNA-B (Santa Cruz sc-44230) as a negative control. Plasmid constructs Human genomic DNA, extracted

(15) Phosphorylation of the pyruvate dehydrogenase complex precedes HIF-1-mediated effects and pyruvate dehydrogenase kinase 1 upregulation during the first hours of hypoxic treatment in hepatocellular carcinoma cellsHypoxia (Auckland, N.Z.)January 1, 2016Zimmer AD, Walbrecq G, Kozar I, Behrmann I, Haan C.

(16) Targeting hypoxia-inducible factor-2α enhances sorafenib antitumor activity via β-catenin/C-Myc-dependent pathways in hepatocellular carcinomaOncology lettersAugust 1, 2015Liu F, Dong X, Lv H, Xiu P, Li T, Wang F, Xu Z, Li J.

(17) EFNA3 long noncoding RNAs induced by hypoxia promote metastatic disseminationOncogeneMay 14, 2015Gómez-Maldonado L, Tiana M, Roche O, Prado-Cabrero A, Jensen L, Fernandez-Barral A, Guijarro-Muñoz I, Favaro E, Moreno-Bueno G, Sanz L, et al.

(18) PACAP38/PAC1 signaling induces bone marrow-derived cells homing to ischemic brainStem CellsApril 1, 2015Lin CH, Chiu L, Lee HT, Chiang CW, Liu SP, Hsu YH, Lin SZ, Hsu CY, Hsieh CH, Shyu WC.

(19) c-Myc-mediated repression of miR-15-16 in hypoxia is induced by increased HIF-2α and promotes tumor angiogenesis and metastasis by upregulating FGF2OncogeneMarch 12, 2015Xue G, Yan HL, Zhang Y, Hao LQ, Zhu XT, Mei Q, Sun SH.Life Technologies, Carlsbad, CA, USA). The siRNA for c-Myc (sc-29226), FGF2 (sc-39446), HIF-1α (sc-35561), HIF-2α (sc-35316), Mad1 (sc-38073), Max (sc-38079) and BCL2 (sc-29214) were purchased from Santa Cruz Bitoechnology (Santa

(20) Hypoxia-inducible factor-1β (HIF-1β) is upregulated in a HIF-1α-dependent manner in 518A2 human melanoma cells under hypoxic conditionsBiochemical and biophysical research communicationsApril 26, 2013Mandl M, Kapeller B, Lieber R, Macfelda K.

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EPAS-1 siRNA (h)

EPAS-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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EPAS-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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