Stat1 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemStat1 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44124
Gene Namesignal transducer and activator of transcription 1, 91kDa
Quantity10 µM
Speciesmouse
NCBI Full Gene Namesignal transducer and activator of transcription 1
NCBI Gene Aliases2010005J02Rik
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1αFrontiers in immunologyJanuary 1, 2023Han Y, Li G, Zhang Z, Zhang X, Zhao B, Yang H.M-CSF. Cells were transfected with 100 nM control scramble (6568, CST, USA) or 100 nM STAT1 siRNA (sc-44124, Santa Cruz, USA) using Lipofectamine™ 3000 (L3000001, Invitrogen, USA) according to the manufacturers’

(2) LAG-3 expression in microglia regulated by IFN-γ/STAT1 pathway and metalloproteasesFrontiers in cellular neuroscienceJanuary 1, 2023Morisaki Y, Ohshima M, Suzuki H, Misawa H.the manufacturer’s instructions, the cells were then transfected with 100 nM siRNA targeting STAT1 (sc-44124, Santa Cruz Biotechnology) or LAG-3 (sc-44548, Santa Cruz Biotechnology). Scrambled control siRNA-A

(3) TNFSF15 facilitates differentiation and polarization of macrophages toward M1 phenotype to inhibit tumor growthOncoimmunologyJanuary 1, 2022Zhao CC, Han QJ, Ying HY, Gu XX, Yang N, Li LY, Zhang QZ.

(4) Downregulation of STAT1 induces the differentiation of neural stem cells through JNK pathwayTissue & cellDecember 1, 2019Liu Y, Yu M, Jiang D.

(5) Protective effect of silencing Stat1 on high glucose-induced podocytes injury via Forkhead transcription factor O1-regulated the oxidative stress responseBMC molecular and cell biologyJuly 23, 2019Wang H, Zhang Y, Xia F, Zhang W, Chen P, Yang G.San Jose, CA, USA). Cell transfection Silencing/over-expressing FoxO1 (sc-425179), silencing Stat1 (sc-44124) and empty control plasmids (sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA,

(6) miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathwayJournal of cellular and molecular medicineNovember 1, 2017Zhu J, Yao K, Guo J, Shi H, Ma L, Wang Q, Liu H, Gao W, Sun A, Zou Y, et al.

(7) IRF-8 is Involved in Amyloid-β(1-40) (Aβ(1-40))-induced Microglial Activation: a New Implication in Alzheimer's DiseaseJournal of molecular neuroscience : MNOctober 1, 2017Zeng Q, Man R, Luo Y, Zeng L, Zhong Y, Lu B, Wang X.

(8) IFN-γ promotes transendothelial migration of CD4(+) T cells across the blood-brain barrierImmunology and cell biologyOctober 1, 2017Sonar SA, Shaikh S, Joshi N, Atre AN, Lal G.

(9) PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosisNature communicationsJuly 17, 2015He C, Medley SC, Hu T, Hinsdale ME, Lupu F, Virmani R, Olson LE.

(10) TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3PLoS pathogensMarch 1, 2015Wang P, Zhao W, Zhao K, Zhang L, Gao C.

(11) Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activationPloS oneJanuary 1, 2015Dicay MS, Hirota CL, Ronaghan NJ, Peplowski MA, Zaheer RS, Carati CA, MacNaughton WK.siRNA’s,Concentration,Transfection Time "STAT1 siRNA (Cat# sc-44124, Santa Cruz Biotechnology)",80 nM,24 hr "STAT3 siRNA (Cat# sc-29494, Santa Cruz Biotechnology)",80

(12) STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-γ/TNF-α-induced apoptosis in NIT-1 cellsPloS oneJanuary 1, 2015Cao ZH, Zheng QY, Li GQ, Hu XB, Feng SL, Xu GL, Zhang KQ.

(13) Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stressNature medicineDecember 1, 2014Hasnain SZ, Borg DJ, Harcourt BE, Tong H, Sheng YH, Ng CP, Das I, Wang R, Chen AC, Loudovaris T, et al.

(14) IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanismThe Journal of biological chemistryApril 25, 2014Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP.

(15) TLR3-triggered reactive oxygen species contribute to inflammatory responses by activating signal transducer and activator of transcription-1Journal of immunology (Baltimore, Md. : 1950)June 15, 2013Yang CS, Kim JJ, Lee SJ, Hwang JH, Lee CH, Lee MS, Jo EK.

(16) Interferon-α induces nitric oxide synthase expression and haem oxygenase-1 down-regulation in microglia: implications of cellular mechanism of IFN-α-induced depressionThe international journal of neuropsychopharmacologyMarch 1, 2013Lu DY, Leung YM, Su KP.

(17) Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplayEMBO molecular medicineMarch 1, 2013Fiorentino L, Cavalera M, Menini S, Marchetti V, Mavilio M, Fabrizi M, Conserva F, Casagrande V, Menghini R, Pontrelli P, et al.

(18) Arsenic trioxide prevents nitric oxide production in lipopolysaccharide -stimulated RAW 264.7 by inhibiting a TRIF-dependent pathwayCancer scienceFebruary 1, 2013Takahashi M, Ota A, Karnan S, Hossain E, Konishi Y, Damdindorj L, Konishi H, Yokochi T, Nitta M, Hosokawa Y.

(19) Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistanceCancer researchSeptember 15, 2012Zimmerman MA, Rahman NT, Yang D, Lahat G, Lazar AJ, Pollock RE, Lev D, Liu K.

(20) STAT1 interacts with RXRα to upregulate ApoCII gene expression in macrophagesPloS oneJanuary 1, 2012Trusca VG, Florea IC, Kardassis D, Gafencu AV.