Stat1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemStat1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44123
Gene Namesignal transducer and activator of transcription 1, 91kDa
Quantity10 µM
Specieshuman
NCBI Full Gene Namesignal transducer and activator of transcription 1
NCBI Gene AliasesCANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Machine learning model reveals roles of interferon‑stimulated genes in sorafenib‑resistant liver cancerOncology LettersJuly 15, 2024Deok Hwa Seo, Ji Woo Park, Hee Won Jung, Min Woo Kang, Byung Yoon Kang, Dong Yeup Lee, Jae Jun Lee, Seung Kew Yoon, Jeong Won Jang, Jae Gyoon Ahn, et al.Huh-7-SR cells were transfected with siControl (Santa Cruz, Cat#sc-37007), siSTAT1 (Santa Cruz, Cat#sc-44123), siSTAT2 (Santa Cruz, Cat#sc-29492), or siIRF9 (OriGene, Cat#SR323091) at a concentration of 10 nM

(2) IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL-8 expression in ovarian cancer cellsFEBS open bioAugust 1, 2023Gaire B, Padmanabhan S, Zou Y, Uddin MM, Reddy SU, Vancurova I.Cell viability was measured by trypan blue. Transfections with siRNA Human JAK1 (sc‐35719), STAT1 (sc‐44123), p65 (sc‐29410), and non‐silencing control (sc‐37007) siRNAs were purchased from Santa Cruz Biotechnology

(3) Advanced Glycation End Products-Induced Activation of Keratinocytes: A Mechanism Underlying Cutaneous Immune Response in PsoriasisJournal of innate immunityJanuary 1, 2023Kang P, Chen J, Wang S, Zhang S, Li S, Guo S, Song P, Liu L, Wang G, Gao T, et al.different concentrations as indicated. Small interfering RNA (siRNA) targeting STAT1 (STAT1 siRNA) (sc-44123, Santa Cruz Biotechnology, USA), STAT3 (STAT3 siRNA) (sc-29493, Santa Cruz Biotechnology, USA), or RAGE

(4) IFNγ-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signalingCellular signallingSeptember 1, 2022Padmanabhan S, Gaire B, Zou Y, Uddin MM, Vancurova I.

(5) MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell AdhesionMolecular Cancer ResearchAugust 5, 2022Saravanakumar Marimuthu, Imayavaramban Lakshmanan, Sakthivel Muniyan, Shailendra K. Gautam, Rama Krishna Nimmakayala, Sanchita Rauth, Pranita Atri, Ashu Shah, Namita Bhyravbhatla, Kavita Mallya, et al.MiaPaCa2 and T3M4 cells, and construct details were described (16). Transient KD of STAT1 siRNA (Cat # sc-44123, Santa Cruz Biotechnology, USA) and NRP2 (Cat# SR305825, OriGene, Rockville MD, USA) were used for silencing

(6) IFNγ induces JAK1/STAT1/p65 NFκB-dependent interleukin-8 expression in ovarian cancer cells, resulting in their increased migrationThe international journal of biochemistry & cell biologyDecember 1, 2021Padmanabhan S, Gaire B, Zou Y, Uddin MM, DeLeon D, Vancurova I.measured by using trypan blue exclusion. 2.2. Transfection with siRNA Human JAK1 (sc-35719), STAT1 (sc-44123), p65 (sc-29410) and non-silencing control (sc-37007) siRNAs were obtained from Santa Cruz Biotechnology

(7) Enhanced IFNα Signaling Promotes Ligand-Independent Activation of ERα to Promote Aromatase Inhibitor Resistance in Breast CancerCancersOctober 13, 2021Escher TE, Dandawate P, Sayed A, Hagan CR, Anant S, Lewis-Wambi J.ERα (Santa Cruz Biotechnology, Dallas, TX, USA, Cat#sc-29305), STAT1 (Santa Cruz Biotechnology, Cat#sc-44123), and STAT2 (Santa Cruz Biotechnology, Cat#sc-29492) or a scrambled negative control (Santa Cruz Biotechnology,

(8) Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progressionCancer lettersAugust 28, 2021Provance OK, Geanes ES, Lui AJ, Roy A, Holloran SM, Gunewardena S, Hagan CR, Weir S, Lewis-Wambi J.MDA-MB-157 and SUM149 cells were transfected with pooled siRNA’s targeting STAT1 (Santa Cruz Biotechnology: sc-44123), STAT2 (Santa Cruz Biotechnology: sc-29492) and IRF9 (Santa Cruz Biotechnology: sc-38013) and harvested

(9) Ruxolitinib induces apoptosis of human colorectal cancer cells by downregulating the JAK1/2-STAT1-Mcl-1 axisOncology lettersMay 1, 2021Li X, Wang Z, Zhang S, Yao Q, Chen W, Liu F.antibody (cat. no. S-19), control siRNA-A (cat. no. sc-37007), and STAT1p84/p91 siRNA (h) (cat. no. sc-44123) were from Santa Cruz Biotechnology, Inc. Anti-STAT1 [phosphorylated (p)S727] (cat. no. ab109461) antibody

(10) BST2 regulates interferon gamma-dependent decrease in invasion of HTR-8/SVneo cells via STAT1 and AKT signaling pathways and expression of E-cadherinCell adhesion & migrationDecember 1, 2020Verma S, Kang AK, Pal R, Gupta SK.

(11) EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expressionScientific reportsJuly 23, 2020Malik A, Pal R, Gupta SK.

(12) STAT1 determines aggressiveness of glioblastoma both in vivo and in vitro through wnt/β-catenin signalling pathwayCell biochemistry and functionJuly 1, 2020Zhao L, Li X, Su J, Wang Gong F, Lu J, Wei Y.

(13) EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancerNature cancerApril 1, 2020Gong K, Guo G, Panchani N, Bender ME, Gerber DE, Minna JD, Fattah F, Gao B, Peyton M, Kernstine K, et al.siRIG-I(sc-61480), siTRIM32(sc-61714), siTBK1(sc-39058), siIRF3(sc-35710), siIFNAR1(sc-35637), siSTAT1(sc-44123), siIFNGR1(sc-29357), siTNFR1(sc-29507), siSTING(sc-92042), and Control siRNA (sc-37007), purchased

(14) Constitutive activation of the EGFR-STAT1 axis increases proliferation of meningioma tumor cellsNeuro-oncology advancesJanuary 1, 2020Ferluga S, Baiz D, Hilton DA, Adams CL, Ercolano E, Dunn J, Bassiri K, Kurian KM, Hanemann CO.

(15) Growth inhibition and transcriptional effects of ribavirin in lymphomaOncology reportsSeptember 1, 2019Dominguez-Gomez G, Cortez-Pedroza D, Chavez-Blanco A, Taja-Chayeb L, Hidalgo-Miranda A, Cedro-Tanda A, Beltran-Anaya F, Diaz-Chavez J, Schcolnik-Cabrera A, Gonzalez-Fierro A, et al.

(16) STAT1 drives M1 microglia activation and neuroinflammation under hypoxiaArchives of biochemistry and biophysicsJuly 15, 2019Butturini E, Boriero D, Carcereri de Prati A, Mariotto S.

(17) Role of STAT signaling and autocrine action of chemokines during H(2) O (2) induced HTR-8/SVneo trophoblastic cells invasionJournal of cellular physiologyFebruary 1, 2019Banerjee P, Malik A, Malhotra SS, Gupta SK.

(18) Inhibition of MEK with trametinib enhances the efficacy of anti-PD-L1 inhibitor by regulating anti-tumor immunity in head and neck squamous cell carcinomaOncoimmunologyJanuary 1, 2019Kang SH, Keam B, Ahn YO, Park HR, Kim M, Kim TM, Kim DW, Heo DS.

(19) The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosisThe Journal of biological chemistryDecember 28, 2018Hu S, Han R, Shi J, Zhu X, Qin W, Zeng C, Bao H, Liu Z.

(20) Interferon gamma decreases intestinal epithelial aquaporin 3 expression through downregulation of constitutive transcriptionJournal of molecular medicine (Berlin, Germany)October 1, 2018Peplowski MA, Dicay M, Baggio CH, Wysokinski F, Renaux B, Hollenberg MD, Proud D, MacNaughton WK.

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Stat1 siRNA (h)

Stat1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Stat1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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