HIF-1α siRNA (h2) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHIF-1α siRNA (h2)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44225
Gene Namehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Quantity10 µM
Specieshuman
NCBI Full Gene Namehypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit
NCBI Gene AliasesHIF1-alpha, HIF1, MOP1, HIF-1-alpha, PASD8, HIF-1A, HIF1-ALPHA, HIF1alpha, bHLHe78, HIF-1alpha
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A potential signaling axis between RON kinase receptor and hypoxia-inducible factor-1 alpha in pancreatic cancerMolecular carcinogenesisNovember 1, 2021Kato A, Ng S, Thangasamy A, Han H, Zhou W, Raeppel S, Fallon M, Guha S, Ammanamanchi S.

(2) Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumorsOncogeneAugust 1, 2021Casillas AL, Chauhan SS, Toth RK, Sainz AG, Clements AN, Jensen CC, Langlais PR, Miranti CK, Cress AE, Warfel NA.protocol (Lipofectamine 3000 Invitrogen). HIF-1α and siRNA was purchased from Santa Cruz Biotechnology (sc-44225 and sc-35316, respectively). PIM1 siRNA sequences were previously reported [58]. The following western blot

(3) The Roles of HIF-1α in Radiosensitivity and Radiation-Induced Bystander Effects Under HypoxiaFrontiers in cell and developmental biologyJanuary 1, 2021Zhang J, Zhang Y, Mo F, Patel G, Butterworth K, Shao C, Prise KM.cytochalasin B (CB), and 7-aminoflavone (AF) were purchased from Sigma (United Kingdom). HIF-1α siRNA (h2, sc-44225) and control siRNA were purchased from Santa Cruz Biotechnology, Inc (United Kingdom). Lipofectamine

(4) Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell deathBiochimica et biophysica acta. Molecular basis of diseaseJuly 1, 2020Yago-Ibáñez J, García-Pastor C, Lucio-Cazaña FJ, Fernández-Martínez AB.

(5) miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell MaturationFrontiers in physiologyJanuary 1, 2018Song N, Zhang T, Xu X, Lu Z, Yu X, Fang Y, Hu J, Jia P, Teng J, Ding X."Thermo Fisher Scientific (MA, USA)",15596-026 Human HIF-1α siRNAs,"Santa Cruz Biotechnology, Inc. (TX, USA)",sc-44225 Human HIF-2α (EPAS-1) siRNAs,"Santa Cruz Biotechnology, Inc. (TX, USA)",sc-35316 Human scramble siRNAs,"Santa Cruz Biotechnology, Inc

(6) EGF regulation of proximal tubule cell proliferation and VEGF-A secretionPhysiological reportsSeptember 1, 2017Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP.transfection At 70% confluence, HK‐2 cells were transiently transfected with 23 nmol/L HIF‐1α siRNA (Santa Cruz, sc‐44225) or scrambled siRNA (Santa Cruz, sc‐37007) using Lipofectamine RNAiMAX™ Transfection Reagent (Life Technologies,

(7) HIF-1α induction during reperfusion avoids maladaptive repair after renal ischemia/reperfusion involving miR127-3pScientific reportsJanuary 20, 2017Conde E, Giménez-Moyano S, Martín-Gómez L, Rodríguez M, Ramos ME, Aguado-Fraile E, Blanco-Sanchez I, Saiz A, García-Bermejo ML.different HIF-1 α siRNAs (Customized Silencer Select siRNAs: S225214, S225215, S225216 Ambion; siRNA sc-44225, Santa Cruz Biotechnologies) and scrambledd siRNA (sc-37007, Santa Cruz Biotechnologies), using Lipofectamine

(8) Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxiaNucleic acids researchNovember 2, 2016Roche O, Deguiz ML, Tiana M, Galiana-Ribote C, Martinez-Alcazar D, Rey-Serra C, Ranz-Ribeiro B, Casitas R, Galera R, Fernández-Navarro I, et al.time quantitative PCR and western blot analyses. We used commercial siRNAs, HIF1A siRNA (Santa Cruz, sc-44225), EPAS1 siRNA (Santa Cruz sc-35316) and siRNA-B (Santa Cruz sc-44230) as a negative control. Plasmid

(9) Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2OncotargetSeptember 27, 2016Yaghi L, Poras I, Simoes RT, Donadi EA, Tost J, Daunay A, de Almeida BS, Carosella ED, Moreau P.transfection efficiency and protein extracts preparation. The HIF-1α shRNA plasmid and the control shRNA Plasmid A (Sc-44225 and Sc-108060, Santa Cruz Biotechnology, Inc, Santa Cruz, CA) were used to silence HIF-1α expression

(10) EFNA3 long noncoding RNAs induced by hypoxia promote metastatic disseminationOncogeneMay 14, 2015Gómez-Maldonado L, Tiana M, Roche O, Prado-Cabrero A, Jensen L, Fernandez-Barral A, Guijarro-Muñoz I, Favaro E, Moreno-Bueno G, Sanz L, et al.

(11) Cobalt chloride induces neuronal differentiation of human mesenchymal stem cells through upregulation of microRNA-124aBiochemical and biophysical research communicationsFebruary 21, 2014Jeon ES, Shin JH, Hwang SJ, Moon GJ, Bang OY, Kim HH.

(12) The role of hypoxia inducible factor-1 alpha in bypassing oncogene-induced senescencePloS oneJanuary 1, 2014Kilic Eren M, Tabor V.

(13) Epidermal growth factor receptor transactivation by intracellular prostaglandin E2-activated prostaglandin E2 receptors. Role in retinoic acid receptor-β up-regulationBiochimica et biophysica actaSeptember 1, 2013Fernández-Martínez AB, Lucio Cazaña FJ.

(14) Outcome of acute renal injury in diabetic mice with experimental endotoxemia: role of hypoxia-inducible factor-1 αJournal of diabetes researchJanuary 1, 2013Ortega A, Fernández A, Arenas MI, López-Luna P, Muñóz-Moreno C, Arribas I, Olea N, García-Bermejo L, Lucio-Cazana J, Bosch RJ.antibody (Calbiochem-Merk Bioscience, USA) as loading control. For HIF-1𝛼 inhibition, we used HIF-1𝛼 siRNA sc-44225 (Santa Cruz Biotechnologies, CA, USA) for HIF-1𝛼 containing 3 sequences against 3 different HIF-1𝛼 exons

(15) Non-hypoxic stabilization of HIF-Iα during coordinated interaction between Akt and angiopoietin-1 enhances endothelial commitment of bone marrow stem cellsJournal of molecular medicine (Berlin, Germany)June 1, 2012Lai VK, Afzal MR, Ashraf M, Jiang S, Haider HKh.

(16) miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 targetPloS oneJanuary 1, 2012Aguado-Fraile E, Ramos E, Sáenz-Morales D, Conde E, Blanco-Sánchez I, Stamatakis K, del Peso L, Cuppen E, Brüne B, Bermejo ML.siRNA Transfection in vitro HK2 cells at 80% of confluence were transfected with 100 nM HIF-1α siRNA (sc-44225, Santa Cruz Biotechnologies, Santa Cruz, CA, USA) or scramble siRNA (sc-37007, Santa Cruz Biotechnologies),

(17) Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survivalPloS oneJanuary 1, 2012Conde E, Alegre L, Blanco-Sánchez I, Sáenz-Morales D, Aguado-Fraile E, Ponte B, Ramos E, Sáiz A, Jiménez C, Ordoñez A, et al.different HIF-1 α siRNAs (Customized Silencer Select siRNAs: S225214, S225215, S225216 Ambion; siRNA sc-44225, Santa Cruz Biotechnologies) and scramble siRNA (sc-37007, Sta Cruz Biotechnologies), using Lipofectamine

(18) Mutual regulation of hypoxic and retinoic acid related signalling in tubular proximal cellsThe international journal of biochemistry & cell biologyAugust 1, 2011Fernández-Martínez AB, Jiménez MI, Hernández IS, García-Bermejo ML, Manzano VM, Fraile EA, de Lucio-Cazaña FJ.

(19) Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expressionPloS oneJanuary 1, 2011Miró-Murillo M, Elorza A, Soro-Arnáiz I, Albacete-Albacete L, Ordoñez A, Balsa E, Vara-Vega A, Vázquez S, Fuertes E, Fernández-Criado C, et al.Biosystems). siRNA transfection HL-1 cells were transfected with a siRNA targeting mouse HIF-1α (50 nM, sc-44225: Santa Cruz) or a scrambled control siRNA (sc-37007), using Lipofectamine 2000 (Invitrogen) according

(20) Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1PloS oneMarch 12, 2010Pescador N, Villar D, Cifuentes D, Garcia-Rocha M, Ortiz-Barahona A, Vazquez S, Ordoñez A, Cuevas Y, Saez-Morales D, Garcia-Bermejo ML, et al.

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HIF-1α siRNA (h2)

HIF-1α siRNA (h2) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HIF-1α siRNA (h2) from Santa Cruz Biotechnology, Inc.

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