PP2A-Cα siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPP2A-Cα siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43509
Gene Nameprotein phosphatase 2, catalytic subunit, alpha isozyme
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein phosphatase 2 catalytic subunit alpha
NCBI Gene AliasesNEDLBA, PP2Ac, PP2CA, PP2Calpha, RP-C
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Cigarette smoke alters calcium flux to induce PP2A membrane trafficking and endothelial cell permeabilityScientific ReportsNovember 14, 2024Abdoulaye J. Dabo, Sonya Raghavan, Wendy Ezegbunam, Jincy Thankachen, Oleg Evgrafov, Sue Majka, Patrick Geraghty, Robert F. Foronjy(NSMase) siRNA, PP2A siRNA or scrambled siRNA (Santa Cruz, Santa Cruz, CA, PTP1B- sc-36328, PP2A-C sc-43509, NSmase- sc-62655). Calcium release assay and calcium switch studies. Primary human lung microvascular

(2) Piezo1 – Serine/threonine-protein phosphatase 2A – Cofilin1 biochemical mechanotransduction axis controls F-actin dynamics and cell migrationHeliyonJune 15, 2024Francesco Morena, Chiara Argentati, Silvia Caponi, Ines Lüchtefeld, Carla Emiliani, Massimo Vassalli, Sabata Martinoat 18 h under the same experimental conditions. 4.8 siRNA cell transfection The PP2A-C siRNA(h) (sc-43509), Cofilin 1 siRNA (h) (sc-35078), and control siRNA (sc-37007) were purchased from Santa Cruz Biotechnology.

(3) IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathwayLife Science AllianceOctober 1, 2023Cristina Cariulo, Paola Martufi, Margherita Verani, Leticia Toledo-Sherman, Ramee Lee, Celia Dominguez, Lara Petricca, Andrea Caricasoledescribed. Silencing via RNAi was performed using specific PP2A-Cα siRNA commercially supplied (catalog #sc-43509; Santa Cruz Biotechnology). The siRNA transfection was performed as reported above, using the siRNAs

(4) PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activityMolecular biology of the cellMarch 1, 2022Hasegawa J, Tokuda E, Yao Y, Sasaki T, Inoki K, Weisman LS.transfection. RNA interference For knockdown of human PP2A-Cα and PP2A-Cβ, siRNAs were purchased from Santa Cruz (sc-43509 and sc-39175), and for knockdown of human PIKfyve, siRNA was purchased from Thermo Fisher Scientific

(5) Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 ActivityCell reportsApril 14, 2020Ohba S, Johannessen TA, Chatla K, Yang X, Pieper RO, Mukherjee J.

(6) DR region of Na⁺-K⁺-ATPase is a new target to protect heart against oxidative injuryScientific reportsAugust 30, 2018Hua F, Wu Z, Yan X, Zheng J, Sun H, Cao X, Bian JS.

(7) Protein phosphatase 2A mediates JS-K-induced apoptosis by affecting Bcl-2 family proteins in human hepatocellular carcinoma HepG2 cellsJournal of cellular biochemistryAugust 1, 2018Liu L, Huang Z, Chen J, Wang J, Wang S.

(8) Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cellsJournal of experimental & clinical cancer research : CRJuly 9, 2018Liu L, Huang Z, Chen J, Wang J, Wang S.

(9) Hyperglycemia triggers HIPK2 protein degradationOncotargetJanuary 3, 2017Baldari S, Garufi A, Granato M, Cuomo L, Pistritto G, Cirone M, D'Orazi G.

(10) Isoliensinine induces dephosphorylation of NF-kB p65 subunit at Ser536 via a PP2A-dependent mechanism in hepatocellular carcinoma cells: roles of impairing PP2A/I2PP2A interactionOncotargetJune 28, 2016Shu G, Zhang L, Jiang S, Cheng Z, Wang G, Huang X, Yang X.

(11) Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer developmentScientific reportsAugust 13, 2015Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.mutation in the NIK coding sequence using mutagenic primers. The small interfering RNA (siRNA) of PP2Acα (sc-43509) and control (6568) were purchased from Santa Cruz and Cell Signaling Technology, respectively15. The

(12) CIP2A mediates erlotinib-induced apoptosis in non-small cell lung cancer cells without EGFR mutationLung cancer (Amsterdam, Netherlands)August 1, 2014Wang CY, Chao TT, Chang FY, Chen YL, Tsai YT, Lin HI, Huang YC, Shiau CW, Yu CJ, Chen KF.

(13) Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancersNature communicationsFebruary 26, 2014Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, et al.A control shRNA vector targeting luciferase (shLuc) was purchased from Clontech. The PP2Acα siRNA (sc-43509) and control siRNA (6568) were purchased from Santa Cruz Biotechnology and Cell Signaling Technology,

(14) Neuroprotective effects of donepezil against Aβ42-induced neuronal toxicity are mediated through not only enhancing PP2A activity but also regulating GSK-3β and nAChRs activityJournal of neurochemistryNovember 1, 2013Noh MY, Koh SH, Kim SM, Maurice T, Ku SK, Kim SH.

(15) Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylationThe Journal of biological chemistryMay 10, 2013Li Y, Wang X, Yue P, Tao H, Ramalingam SS, Owonikoko TK, Deng X, Wang Y, Fu H, Khuri FR, et al.

(16) Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: implications for breast cancerFree radical biology & medicineApril 1, 2013Sen S, Kawahara B, Chaudhuri G.

(17) Gene-specific factors determine mitotic expression and bookmarking via alternate regulatory elementsNucleic acids researchFebruary 1, 2013Arampatzi P, Gialitakis M, Makatounakis T, Papamatheakis J.the hybridoma cell line Myc-9E10.2 (38) and anti-CIITA antibody was described earlier (39). PP2A-Cα (sc-43509) and PP2A-Cβ (sc-36301) siRNAs were from Santa Cruz Biotechnology and siSCR (scrambled) was from CUREVAC.

(18) Induction of a feed forward pro-apoptotic mechanistic loop by nitric oxide in a human breast cancer modelPloS oneJanuary 1, 2013Sen S, Kawahara B, Fukuto J, Chaudhuri G.subunit [NM _002715] and FOXO1 [NM_002015.3] were obtained from Santa Cruz biotech, PP2A Cα siRNA [Sc-43509] and FOXO1siRNA [Sc-35383] respectively were obtained from Santa Cruz Biotech Non-specific, scrambled

(19) Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivationFEBS open bioJanuary 1, 2013Webster Marketon JI, Corry J.protein phosphatase 2A (PP2A-Cα) siRNA and control siRNA-A (Santa Cruz Biotechnology; sc-44602, sc-43545, sc-43509 and sc-37007, respectively) was transfected into A549 cells using DharmaFECT 2 (Thermo Fisher Scientific

(20) Maintenance of higher H₂O₂ levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2AFree radical biology & medicineOctober 15, 2012Sen S, Kawahara B, Chaudhuri G.

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PP2A-Cα siRNA (h)

PP2A-Cα siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PP2A-Cα siRNA (h) from Santa Cruz Biotechnology, Inc.

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