O-GlcNAc transferase siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemO-GlcNAc transferase siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-40780
Quantity10 µM
Gene NameO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NameO-linked N-acetylglucosamine (GlcNAc) transferase
NCBI Gene AliasesHINCUT-1, HRNT1, MRX106, O-GLCNAC, OGT1, XLID106

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Modulation of O-GlcNAc cycling influences α-synuclein amplification, degradation, and associated neuroinflammatory pathologyMol NeurodegenerOctober 27, 2025Yongzhen Miao, Ting Zhang, Zhuoya Ma, Huanhuan Du, Qipei Gu, Mengni Jiang, Kangping Xiong, Chun-Feng Liu, Hongrui Mengdata collection. Transfection of cells with OGT small-interference RNA OGT small-interference RNA (siRNA) (Santa Cruz, sc-40780) was utilized to knock down OGT expression in SH-SY5Y cells. Transfections were carried out using the

(2) Selective bioorthogonal probe for N-glycan hybrid structuresNature Chemical BiologyMay 1, 2025Mana Mohan Mukherjee, Devin Biesbrock, Lara K. Abramowitz, Lara K. Abramowitz, Bhoj Kumar, Peter J. Walter, Parastoo Azadi, Kenneth A. Jacobson, John A. Hanoverreagents were purchased from Santa Cruz: transfection reagent (sc-29528), MGAT1 siRNA construct (human) (sc-40780), and Control siRNA-A (sc-37007). The lyophilized siRNA duplex was resuspended in 330 μL (MGAT1) or

(3) High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cellsiScienceJanuary 19, 2024Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T.(h),Santa Cruz Biotechnology,Cat# sc-29487 OGT siRNA and shRNA Plasmids (h),Santa Cruz Biotechnology,Cat# sc-40780 mouse OGT siRNA5’-AGGGAACUAGAUAACAUGCUU-3′,This paper,N/A Human OGA siRNA5’-ACTCATCCCACGGTTAAAA-3’,This

(4) Tools and tactics to define specificity of metabolic chemical reportersFrontiers in molecular biosciencesJanuary 1, 2023Mukherjee MM, Bond MR, Abramowitz LK, Biesbrock D, Woodroofe CC, Kim EJ, Swenson RE, Hanover JA.transfection reagent (sc-29528), NCOAT siRNA construct (human) (sc-62667), OGT siRNA construct (human) (sc-40780), and Control siRNA-A (sc-37007). Lyophilized siRNA duplex was resuspended in 330 μL (NCOAT and OGT)

(5) Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stressNature chemical biologyFebruary 1, 2022Shu XE, Mao Y, Jia L, Qian SB.

(6) O-GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activityJournal of cellular physiologyNovember 1, 2021Huang H, Wu Q, Guo X, Huang T, Xie X, Wang L, Liu Y, Shi L, Li W, Zhang J, et al.

(7) DNA-PKcs Ser2056 auto-phosphorylation is affected by an O-GlcNAcylation/phosphorylation interplayBiochimica et biophysica acta. General subjectsDecember 1, 2020Lafont F, Fleury F, Benhelli-Mokrani H.

(8) O-GlcNAc Transferase Inhibitor Synergistically Enhances Doxorubicin-Induced Apoptosis in HepG2 CellsCancersOctober 27, 2020Lee SJ, Kwon OS.

(9) Resistance to bortezomib in breast cancer cells that downregulate Bim through FOXA1 O-GlcNAcylationJournal of cellular physiologyAugust 1, 2019Liu Y, Wang X, Zhu T, Zhang N, Wang L, Huang T, Cao Y, Li W, Zhang J.

(10) O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetesBiochimica et biophysica acta. General subjectsJune 1, 2019Chen CH, Lin KD, Ke LY, Liang CJ, Kuo WC, Lee MY, Lee YL, Hsiao PJ, Hsu CC, Shin SJ.

(11) Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelial-mesenchymal transition and invasion in breast cancer cellsCell death & diseaseApril 24, 2019Zhang N, Zhu T, Yu K, Shi M, Wang X, Wang L, Huang T, Li W, Liu Y, Zhang J.using the Lipofectamine 2000 transfection reagent following the manufacturer’s instructions. OGT siRNA (sc-40780), GFAT siRNA (sc-6068), CEBPB siRNA (sc-29862), CHOP siRNA (sc-156118), XBP1 siRNA (sc-38627) and scrambled

(12) O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock responseNature chemical biologyOctober 1, 2018Zhang X, Shu XE, Qian SB.

(13) O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistanceCell death & diseaseMay 1, 2018Liu Y, Cao Y, Pan X, Shi M, Wu Q, Huang T, Jiang H, Li W, Zhang J.using the Lipofectamine 2000 transfection reagent following the manufacturer’s instructions. OGT siRNA (sc-40780), GFAT siRNA (sc-6068), XBP1 siRNA (sc-38627), GRP78 siRNA (sc-29338) and scrambled siRNA (sc-37007)

(14) Regulation of miR-483-3p by the O-linked N-acetylglucosamine transferase links chemosensitivity to glucose metabolism in liver cancer cellsOncogenesisMay 8, 2017Pepe F, Pagotto S, Soliman S, Rossi C, Lanuti P, Braconi C, Mariani-Costantini R, Visone R, Veronese A.(AMO negative control) were from Fidelity System (Gaithersburg, MD, USA). RNA interfering for OGT (sc-40780) and scramble control (sc-37007) were from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Transfection

(15) Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cellsOncotargetJune 28, 2016Kang KA, Piao MJ, Ryu YS, Kang HK, Chang WY, Keum YS, Hyun JW.

(16) Chitosan oligosaccharides block LPS-induced O-GlcNAcylation of NF-κB and endothelial inflammatory responseCarbohydrate polymersJanuary 1, 2014Li Y, Liu H, Xu QS, Du YG, Xu J.

(17) Identification of nitric oxide as an endogenous inhibitor of 26S proteasomes in vascular endothelial cellsPloS oneJanuary 1, 2014Liu H, Yu S, Zhang H, Xu J.

(18) Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT)PloS oneJanuary 1, 2012Xu J, Wang S, Viollet B, Zou MH.

(19) Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic conditionThe EMBO journalNovember 17, 2010Park SY, Kim HS, Kim NH, Ji S, Cha SY, Kang JG, Ota I, Shimada K, Konishi N, Nam HW, et al.

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