Stat3 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemStat3 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29494
Gene Namesignal transducer and activator of transcription 3 (acute-phase response factor)
Quantity10 µM
Speciesmouse
NCBI Full Gene Namesignal transducer and activator of transcription 3
NCBI Gene Aliases1110034C02Rik, Aprf
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The canonical ER stress IRE1α/XBP1 pathway mediates skeletal muscle wasting during pancreatic cancer cachexiaEMBO Molecular MedicineNovember 17, 2025Aniket S Joshi, Meiricris Tomaz da Silva, Anh Tuan Vuong, Bowen Xu, Ravi K Singh, Ashok Kumar(m),Santa Cruz Biotechnology Inc.,Cat # sc-38628 STAT3 siRNA (m),Santa Cruz Biotechnology Inc.,Cat # sc-29494 Mouse Xbp1 (exon 2) Forward Primer-5’-CCTGAGCCCGGAGGAGAA-3’,"Chen et al, 2018",N/A Mouse Xbp1 (exon

(2) Leucine zipper protein 1 attenuates pressure overload-induced cardiac hypertrophy through inhibiting Stat3 signalingJournal of Advanced ResearchSeptember 1, 2024Di Fan, Wan-li Jiang, Zhi-li Jin, Jian-lei Cao, Yi Li, Tao He, Wei Zhang, Li Peng, Hui-xia Liu, Xiao-yan Wu, et al.inhibit ROCK [21], [22]. For Stat3 silence in vitro, NRCMs were transfected with 50 nmol/L siStat3 (#sc-29494; Santa Cruz, Dallas, Texas, USA) for 6 h, and subsequently cultured in fresh medium for 24 h before

(3) Insulin augments angiotensin II-induced myocardial fibrosis via the MEK/STAT3 pathwayHeliyonNovember 25, 2023Nanyu Cao, Heyang Wangsilencing was performed by transfection with small interfering RNAs (siRNAs) against STAT3 and STAT5 (sc-29494 and sc-29496; Santa Cruz Biotechnology, USA) as described in our previous study [20]. To examine the

(4) The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe^-/- Mice through Modulating Macrophage FunctionsBiomedicinesSeptember 3, 2021Qian Z, Yang H, Li H, Liu C, Yang L, Qu Z, Li X.Interfering RNA (siRNA) SiRNAs of the target genes, including siTNFAIP3 (Cat# sc-37656), siSTAT3 (Cat# sc-29494), siCD36 (Cat# sc-37245), siABCG1 (Cat# sc-41139), and the corresponding negative control RNAs (si-NC)

(5) Silencing STAT3 enhances sensitivity of cancer cells to doxorubicin and inhibits tumor progressionLife sciencesJune 15, 2021Joshi N, Hajizadeh F, Ansari Dezfouli E, Zekiy AO, Nabi Afjadi M, Mousavi SM, Hojjat-Farsangi M, Karpisheh V, Mahmoodpoor A, Hassannia H, et al.

(6) Blockade of HIF-1α and STAT3 by hyaluronate-conjugated TAT-chitosan-SPION nanoparticles loaded with siRNA molecules prevents tumor growthNanomedicine : nanotechnology, biology, and medicineJune 1, 2021Budi HS, Izadi S, Timoshin A, Asl SH, Beyzai B, Ghaderpour A, Alian F, Eshaghi FS, Mousavi SM, Rafiee B, et al.

(7) Codelivery of STAT3 and PD-L1 siRNA by hyaluronate-TAT trimethyl/thiolated chitosan nanoparticles suppresses cancer progression in tumor-bearing miceLife sciencesFebruary 1, 2021Bastaki S, Aravindhan S, Ahmadpour Saheb N, Afsari Kashani M, Evgenievich Dorofeev A, Karoon Kiani F, Jahandideh H, Beigi Dargani F, Aksoun M, Nikkhoo A, et al.

(8) linc-AAM Facilitates Gene Expression Contributing to Macrophage Activation and Adaptive Immune ResponsesCell reportsJanuary 5, 2021Chen X, He Y, Zhu Y, Du J, Sun H.

(9) MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cellsThe Journal of biological chemistryJanuary 1, 2021Han Y, Zhang J, Huang S, Cheng N, Zhang C, Li Y, Wang X, Liu J, You B, Du J.

(10) Glycyrrhizic acid facilitates anti-tumor immunity by attenuating Tregs and MDSCs: An immunotherapeutic approachInternational immunopharmacologyNovember 1, 2020Juin SK, Ghosh S, Majumdar S.

(11) Silencing of p68 and STAT3 synergistically diminishes cancer progressionLife sciencesMay 15, 2020Hashemi V, Ahmadi A, Malakotikhah F, Chaleshtari MG, Baghi Moornani M, Masjedi A, Sojoodi M, Atyabi F, Nikkhoo A, Rostami N, et al.

(12) Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progressionInternational journal of biological macromoleculesApril 15, 2020Masjedi A, Ahmadi A, Atyabi F, Farhadi S, Irandoust M, Khazaei-Poul Y, Ghasemi Chaleshtari M, Edalati Fathabad M, Baghaei M, Haghnavaz N, et al.

(13) Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosiseLifeJanuary 14, 2020Bao Q, Zhang B, Suo Y, Liu C, Yang Q, Zhang K, Yuan M, Yuan M, Zhang Y, Li G.primary CFs were seeded on plates and cultured to 80% confluence, then transfected with Stat3 siRNA (#sc-29494) or control siRNA (#sc-37007, both Santa Cruz Biotechnology, CA) by using Lipofectamine RNAi MAX transfection reagent

(14) Tumor Arrests DN2 to DN3 Pro T Cell Transition and Promotes Its Conversion to Thymic Dendritic Cells by Reciprocally Regulating Notch1 and Ikaros SignalingFrontiers in immunologyJanuary 1, 2020Guha I, Bhuniya A, Shukla D, Patidar A, Nandi P, Saha A, Dasgupta S, Ganguly N, Ghosh S, Nair A, et al.

(15) Panax notoginseng saponins modulate the gut microbiota to promote thermogenesis and beige adipocyte reconstruction via leptin-mediated AMPKα/STAT3 signaling in diet-induced obesityTheranosticsJanuary 1, 2020Xu Y, Wang N, Tan HY, Li S, Zhang C, Zhang Z, Feng Y.after the induction of beige differentiation) were transfected with a mouse siRNA targeting STAT 3 (SC-29494) or AMPKα1/2 (sc-45313) or control siRNA (sc-37007) purchased from Santa Cruz Biotechnology (Reston,

(16) Neem Leaf Glycoprotein Restrains VEGF Production by Direct Modulation of HIF1α-Linked Upstream and Downstream CascadesFrontiers in oncologyJanuary 1, 2020Saha A, Nandi P, Dasgupta S, Bhuniya A, Ganguly N, Ghosh T, Guha I, Banerjee S, Baral R, Bose A.

(17) NLGP counterbalances the immunosuppressive effect of tumor-associated mesenchymal stem cells to restore effector T cell functionsStem cell research & therapySeptember 23, 2019Ghosh T, Nandi P, Ganguly N, Guha I, Bhuniya A, Ghosh S, Sarkar A, Saha A, Dasgupta S, Baral R, et al.

(18) TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cellsScientific reportsSeptember 9, 2019Whillock AL, Mambetsariev N, Lin WW, Stunz LL, Bishop GA.

(19) Metformin alleviates inflammatory response in non-alcoholic steatohepatitis by restraining signal transducer and activator of transcription 3-mediated autophagy inhibition in vitro and in vivoBiochemical and biophysical research communicationsMay 21, 2019Li YL, Li XQ, Wang YD, Shen C, Zhao CY.

(20) IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesisCell death & diseaseApril 30, 2019Liang M, Ma Q, Ding N, Luo F, Bai Y, Kang F, Gong X, Dong R, Dai J, Dai Q, et al.

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Stat3 siRNA (m)

Stat3 siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Stat3 siRNA (m) from Santa Cruz Biotechnology, Inc.

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