HIF-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHIF-1α siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35562
Gene Namehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Quantity10 µM
Speciesmouse
NCBI Full Gene Namehypoxia inducible factor 1, alpha subunit
NCBI Gene AliasesHIF-1-alpha, HIF1-alpha, HIF1alpha, MOP1, bHLHe78
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Pioglitazone reverses alcohol‐induced alterations in alveolar macrophage mitochondrial phenotypeAlcohol, Clinical and Experimental ResearchMay 1, 2024Kathryn M. Crotty, Shayaan A. Kabir, Sarah S. Chang, Ashish J. Mehta, Samantha M. Yeligarprior to extracellular flux assays. HIF-1α was silenced in MH-S cells using 50 μM siRNA for HIF-1α (sc-35562, Santa Cruz, Dallas, TX). MH-S cells at 50% confluency for extracellular flux experiments were serum

(2) HIF-1α/MMP-9 Axis Is Required in the Early Phases of Skeletal Myoblast Differentiation under Normoxia Condition In VitroCellsDecember 16, 2023Flaminia Chellini, Alessia Tani, Martina Parigi, Francesco Palmieri, Rachele Garella, Sandra Zecchi-Orlandini, Roberta Squecco, Chiara Sassoliduplexes (siRNA; 20 nM, Santa Cruz Biotechnology, Santa Cruz, CA, USA) designed to knock-down HIF-1α (sc-35562; Sense: 5′CACCAUGAUAUGUUUACUATT3′, Antisense: 5′UAGUAAACAUAUCAUGGUGTT3′, Sense: 5′CCAGUUGAAUCUUCAGAUATT3′,

(3) Cobalt (II) Chloride Regulates the Invasion and Survival of Brucella abortus 544 in RAW 264.7 Cells and B6 MicePathogens (Basel, Switzerland)May 18, 2022Huy TXN, Nguyen TT, Reyes AWB, Kim H, Min W, Lee HJ, Lee JH, Kim S.are listed in Table 1. 4.7. siRNA Knockdown Cells were transfected with HIF-1α siRNA (Santa Cruz, sc-35562), as previously reported [54]. Briefly, cells were grown at concentrations of 4 × 105 cells per well

(4) HIF-1α/FOXO1 axis regulated autophagy is protective for β cell survival under hypoxia in human isletsBiochimica et biophysica acta. Molecular basis of diseaseMay 1, 2022Liang R, Liu N, Cao J, Liu T, Sun P, Cai X, Zhang L, Liu Y, Zou J, Wang L, et al.

(5) Alcohol-Induced Glycolytic Shift in Alveolar Macrophages Is Mediated by Hypoxia-Inducible Factor-1 AlphaFrontiers in immunologyJanuary 1, 2022Morris NL, Michael DN, Crotty KM, Chang SS, Yeligar SM.of MH-S HIF-1α was silenced in MH-S using transient transfection of a HIF-1α siRNA (Catalog number: sc-35562, Santa Cruz, Dallas, TX, United States), and HIF-1α was induced in MH-S using transient transfection

(6) Lactate increases tumor malignancy by promoting tumor small extracellular vesicles production via the GPR81-cAMP-PKA-HIF-1α axisFrontiers in oncologyJanuary 1, 2022Luo M, Zhu J, Ren J, Tong Y, Wang L, Ma S, Wang J.according to the manufacturer’s instructions. The siRNAs including sequences targeting murine Hif1a (sc-35562), Gpr132 (sc-44371), and Gpr81 (sc-44644) and NC siRNA (sc-37007) were obtained from Santa Cruz Biotechnology

(7) Crucial role of glucosylceramide synthase in the regulation of stem cell-like cancer cells in B16F10 murine melanomaMolecular carcinogenesisDecember 1, 2021Ghosh S, Juin SK, Bhattacharyya Majumdar S, Majumdar S.

(8) Defining a pharmacological inhibitor fingerprint for oxytosis/ferroptosisFree Radical Biology and MedicineAugust 1, 2021David Soriano-Castell, Antonio Currais, Pamela Maherdishes at 5 x 105 cells/dish and 20 pmol ATG5 siRNA (#sc-41446 mouse; #sc41445- human) or HIF1α siRNA (#sc-35562) from Santa Cruz Biotechnology or control siRNA (#1027280) from Qiagen, were used along with RNAi max

(9) Blockade of HIF-1α and STAT3 by hyaluronate-conjugated TAT-chitosan-SPION nanoparticles loaded with siRNA molecules prevents tumor growthNanomedicine : nanotechnology, biology, and medicineJune 1, 2021Budi HS, Izadi S, Timoshin A, Asl SH, Beyzai B, Ghaderpour A, Alian F, Eshaghi FS, Mousavi SM, Rafiee B, et al.

(10) Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in miceCommunications biologyMay 10, 2021Silwal P, Kim JK, Jeon SM, Lee JY, Kim YJ, Kim YS, Seo Y, Kim J, Kim SY, Lee MJ, et al.manufacturer’s instruction. Silencing of HIF-1α was achieved using siRNAs for mouse HIF-1α target sequences (sc-35562, Santa Cruz Biotechnology,) and negative control siRNAs (sc-37007, Santa Cruz Biotechnology). RAW264.7

(11) TGR5 deficiency aggravates hepatic ischemic/reperfusion injury via inhibiting SIRT3/FOXO3/HIF-1ɑ pathwayCell death discoveryNovember 1, 2020Wang Q, Wei S, Li L, Qiu J, Zhou S, Shi C, Shi Y, Zhou H, Lu L.negative control (sc-37007) and specific siRNAs including SIRT3 siRNA (sc-61556), and HIF-1α siRNA (sc-35562) were purchased (Santa Cruz Biotechnology, CA, USA). BMDMs transfection was conducted with Lipofectamine

(12) Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell ProgressionPharmaceutical researchSeptember 17, 2020Izadi S, Moslehi A, Kheiry H, Karoon Kiani F, Ahmadi A, Masjedi A, Ghani S, Rafiee B, Karpisheh V, Hajizadeh F, et al.

(13) Silencing of HIF-1α/CD73 axis by siRNA-loaded TAT-chitosan-spion nanoparticles robustly blocks cancer cell progressionEuropean journal of pharmacologySeptember 5, 2020Hajizadeh F, Moghadaszadeh Ardebili S, Baghi Moornani M, Masjedi A, Atyabi F, Kiani M, Namdar A, Karpisheh V, Izadi S, Baradaran B, et al.

(14) Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H19Journal of molecular and cellular cardiologySeptember 1, 2020Hobuß L, Foinquinos A, Jung M, Kenneweg F, Xiao K, Wang Y, Zimmer K, Remke J, Just A, Nowak J, et al.

(15) Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) PolarizationJournal of immunology (Baltimore, Md. : 1950)May 15, 2020Parmar N, Chandrakar P, Kar S.

(16) DRG2 supports the growth of primary tumors and metastases of melanoma by enhancing VEGF-A expressionThe FEBS journalMay 1, 2020Yoon NA, Jung SJ, Choi SH, Ryu JH, Mani M, Lee UH, Vo MT, Jeon DY, Chung SW, Ju Lee B, et al.

(17) Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiationBiochemical and biophysical research communicationsMarch 5, 2020Liu N, Cai X, Liu T, Zou J, Wang L, Wang G, Liu Y, Ding X, Zhang B, Sun P, et al.

(18) Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac FibrosisMolecular therapy. Nucleic acidsDecember 6, 2019Kenneweg F, Bang C, Xiao K, Boulanger CM, Loyer X, Mazlan S, Schroen B, Hermans-Beijnsberger S, Foinquinos A, Hirt MN, et al.HL-1 cells were transfected with siRNA against HIF1A (Santa Cruz Biotechnology, Santa Cruz, CA, USA, # sc-35562), HIF2A (Thermo Fisher Scientific, #4390771, Darmstadt, Germany), or the corresponding negative controls

(19) Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamicsJournal of geriatric cardiology : JGCDecember 1, 2019Chen X, Yao JM, Fang X, Zhang C, Yang YS, Hu CP, Chen Q, Zhong GW.

(20) HIF-1α-regulated MIF activation and Nox2-dependent ROS generation promote Leishmania amazonensis killing by macrophages under hypoxiaCellular immunologyJanuary 1, 2019Alonso D, Serrano E, Bermejo FJ, Corral RS.

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HIF-1α siRNA (m)

HIF-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HIF-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

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