ENX-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemENX-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35312
Gene Nameenhancer of zeste homolog 2 (Drosophila)
Quantity10 µM
Specieshuman
NCBI Full Gene Nameenhancer of zeste 2 polycomb repressive complex 2 subunit
NCBI Gene AliasesENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) EZH2 inhibition or genetic ablation suppresses cyst growth in autosomal dominant polycystic kidney diseaseJournal of Translational MedicineOctober 29, 2024Jiayi Lv, Bingxue Lan, Lili Fu, Chaoran He, Wei Zhou, Xi Wang, Chenchen Zhou, Zhiguo Mao, Yupeng Chen, Changlin Mei, et al.CA, USA) according to the manufacturer’s instructions 48 h before protein extraction. EZH2 siRNA (#SC-35312, Santa Cruz), CREB siRNA (#SC-29281, Santa Cruz), and plasmid (Addgene: CMV500 A-CREB, #33371) were

(2) Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological MalignanciesJournal of medicinal chemistryOctober 13, 2022Lu D, Wang C, Qu L, Yin F, Li S, Luo H, Zhang Y, Liu X, Chen X, Luo Z, et al.

(3) Discovery of precision targeting EZH2 degraders for triple-negative breast cancerEuropean journal of medicinal chemistryAugust 5, 2022Wang C, Chen X, Liu X, Lu D, Li S, Qu L, Yin F, Luo H, Zhang Y, Luo Z, et al.

(4) CRABP2 accelerates epithelial mesenchymal transition in serous ovarian cancer cells by promoting TRIM16 methylation via upregulating EZH2 expressionEnvironmental toxicologyAugust 1, 2022Xie T, Tan M, Gao Y, Yang H.

(5) HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin ResistanceCancersJuly 23, 2022Xie Y, Shi Z, Qian Y, Jiang C, Liu W, Liu B, Jiang B.°C. HDAC2 siRNA and EZH2 siRNA (ENX-1) were bought from Santa Cruz Biotechnology (Cat# sc-29345, Cat# sc-35312, Dallas, TX, USA). 3-Deazaneplanocin A (DZNep) was purchased from MedChemExpress company (Cat# 120964-45-6,

(6) Failure to EGFR-TKI-based therapy and tumoural progression are promoted by MEOX2/GLI1-mediated epigenetic regulation of EGFR in the human lung cancerEur J CancerJanuary 1, 2022Peralta-Arrieta I, Trejo-Villegas OA, Armas-López L, Ceja-Rangel HA, Ordóñez-Luna MDC, Pineda-Villegas P, González-López MA, Ortiz-Quintero B, Mendoza-Milla C, Zatarain-Barrón ZL, et al.

(7) EZH2 Mediates Proliferation, Migration, and Invasion Promoted by Estradiol in Human Glioblastoma CellsFrontiers in endocrinologyJanuary 1, 2022Del Moral-Morales A, González-Orozco JC, Hernández-Vega AM, Hernández-Ortega K, Peña-Gutiérrez KM, Camacho-Arroyo I.using Lipofectamine RNAiMAX (Thermo Scientific, USA), cells were transfected with an EZH2 siRNA (10 nM, sc-35312, Santa Cruz Biotechnology, USA) or with a control siRNA (10 nM, sc-37007, Santa Cruz Biotechnology,

(8) Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCAJournal of medicinal chemistrySeptember 9, 2021Wang C, Qu L, Li S, Yin F, Ji L, Peng W, Luo H, Lu D, Liu X, Chen X, et al.

(9) Upregulation of miR-138 Increases Sensitivity to Cisplatin in Hepatocellular Carcinoma by Regulating EZH2BioMed research internationalJanuary 1, 2021Zeng T, Luo L, Huang Y, Ye X, Lin J.

(10) Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancerCell death & diseaseDecember 12, 2020Tan X, Zhang Z, Liu P, Yao H, Shen L, Tong JS.are listed in Table 2. Small interfering RNA The siRNAs for the negative control (sc-37007), EZH2 (sc-35312), and p53 (sc-44218) were procured from Santa Cruz Biotechnology. These siRNAs were transfected into

(11) A non-viral nano-delivery system targeting epigenetic methyltransferase EZH2 for precise acute myeloid leukemia therapyJournal of materials chemistry. BSeptember 30, 2020Kaundal B, Kushwaha AC, Srivastava AK, Karmakar S, Choudhury SR.

(12) Long non-coding RNA HEIH suppresses the expression of TP53 through enhancer of zeste homolog 2 in oesophageal squamous cell carcinomaJournal of cellular and molecular medicineSeptember 1, 2020Ding X, Qi C, Min J, Xu Z, Huang K, Tang H.

(13) Unraveling the role of H3K4 trimethylation and lncRNA HOTAIR in SATB1 and DUSP4-dependent survival of virulent Mycobacterium tuberculosis in macrophagesTuberculosis (Edinburgh, Scotland)January 1, 2020Subuddhi A, Kumar M, Majumder D, Sarkar A, Ghosh Z, Vasudevan M, Kundu M, Basu J.

(14) Dephosphorylation-induced EZH2 activation mediated RECK downregulation by ERK1/2 signalingJournal of cellular physiologyAugust 1, 2019Ning S, Ma X.

(15) Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in sclerodermaProceedings of the National Academy of Sciences of the United States of AmericaFebruary 26, 2019Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH.

(16) CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancerScientific reportsJanuary 17, 2019Deng H, Guan X, Gong L, Zeng J, Zhang H, Chen MY, Li G.respectively. For knockdown experiments, a pool of siRNAs targeting EZH2 (Santa Cruz Biotechnology; sc35312) and three EED siRNAs (Integrated DNA Technologies (IDT)) were employed. MCF-7 cells were transfected

(17) Crosstalk Between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in DiabetesInvestigative ophthalmology & visual scienceDecember 1, 2017Duraisamy AJ, Mishra M, Kowluru RA.

(18) Circ100284, via miR-217 regulation of EZH2, is involved in the arsenite-accelerated cell cycle of human keratinocytes in carcinogenesisBiochimica et biophysica acta. Molecular basis of diseaseMarch 1, 2017Xue J, Liu Y, Luo F, Lu X, Xu H, Liu X, Lu L, Yang Q, Chen C, Fan W, et al.

(19) EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cellsOncotargetDecember 20, 2016Cardenas H, Zhao J, Vieth E, Nephew KP, Matei D.transfecting SKOV3 cells with a pool of 3 target-specific small interfering RNA (siRNA) (catalogue#: sc-35312, Santa Cruz Biotechnology, Inc. Dallas, TX) in the presence of the DreamFect Gold transfection reagent

(20) The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphaneMolecular carcinogenesisDecember 1, 2016Fisher ML, Adhikary G, Grun D, Kaetzel DM, Eckert RL.(NA934V) were obtained from GE healthcare (Buckinghamshire, UK). Control-siRNA (sc-37007) and Ezh2-siRNA (sc-35312) were purchased from Santa Cruz (Dallas, TX). Matrigel (354234) and BD Biocoat cell inserts (353097,

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ENX-1 siRNA (h)

ENX-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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ENX-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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