Nrf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNrf2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37030
Gene Namenuclear factor (erythroid-derived 2)-like 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameNFE2 like bZIP transcription factor 2
NCBI Gene AliasesHEBP1, IMDDHH, NRF2, Nrf-2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Drynachromoside A from Drynaria fortunei attenuates oxidative stress and fibrosis of diabetic nephropathy via activating Nrf2 in vitro and in vivoRedox ReportDecember 31, 2025Huankai Yao, Jindong Li, Ruiqing Wu, Dan Du, Fengwei Ai, Yan LiBiotechnology (Dalian, China). Negative control siRNA (NC-siRNA) (Cat. no. sc-37007) and Nrf2-siRNA (Cat. no. sc-37030) together with protein A-agarose (Cat. no. sc-2001) were supplied by Santa Cruz Biotechnology (Dallas,

(2) Heterogeneous expression of immunotherapy response markers in non-small cell lung cancer with hyperactive NRF2 pathway: PD-L1 and beyondRedox BiolOctober 10, 2025Karoline Almeida-Lima, Marcelo Falchetti, Barbara Dos Santos, Marina Delgobo, Rosângela Mayer Gonçalves, Nauana Somensi, Helena Souza Zancanaro, Juan Nóbrega de Freitas, Raquel Nascimento das Neves, Lisléia Golfetto, et al.cells, 1 × 10^5 cells per well in 12-well plates were transfected with siRNAs targeting NFE2L2 (siRNA#1: sc-37030, Santa Cruz; siRNA#2: NFE2L2 Silencer® AM16708, ThermoFisher) or Silencer Negative Control No.1 siRNA

(3) A novel 2-oxopyrrolidine derivative (LN-53) efficiently induces Nrf-2 signaling pathway activation in human epidermal keratinocytesPharmacological reports : PROctober 1, 2025Sarac BE, Nissim L, Karaguzel D, Arik G, Kahremany S, Korshin EE, Gruzman A, Karaaslan C.transient transfection HEKs (with passage number between 4 and 5) were transfected with Nrf-2 siRNA (cat. no. sc-37030) (Santa Cruz Biotechnology, USA) to suppress Nrf-2 gene expression. HEKs at 70,000 cells/well density

(4) Inhibitory Effect of S0859 on the Antioxidant Master Switch Nuclear Factor Erythroid 2-Related Factor 2 in Lung Cancer CellsAntioxidants (Basel)September 28, 2025Eunsun Lee, Jeong Hee Hongmodulate gene expression, A549 cells were transfected with NRF2-targeting small interfering RNA (siNRF2; #sc-37030, Santa Cruz Biotechnology, Dallas, TX, USA) to induce gene knockdown, while HEK293T cells were transfected

(5) Surface-elastic hydrogels delay senescence via the modulation of redox homeostasis and cytoskeletal tensionScientific reportsJuly 1, 2025Kuboki T, Kidoaki S.RNA. MSCs were cultured on the substrates for four days. small interfering RNAs, including scrambles (sc-37030, Santa Cruz Biotech) and NRF2 (sc-37030, Santa Cruz Biotech), were delivered into the cells using the

(6) The Splice Variant of the NCOR2 Gene BQ323636.1 Modulates ACSL4 Expression to Enhance Fatty Acid Metabolism and Support of Tumor Growth in Breast CancerInternational journal of molecular sciencesMay 22, 2025Tsoi H, You CP, Cheung KH, Tse YS, Khoo US.the incubator at 37 °C and supplied with 5% CO2. Small interference RNAs (siRNA) that target NRF2 (sc-37030) and ACSL4 (sc-60619) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Non-targeting

(7) SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCFFBXO22–BACH1 complex in triple-negative breast cancerThe EMBO JournalApril 22, 2025Phi-Long Tran, Okhwa Kim, Cheol Hwangbo, Hyo-Jin Kim, Young-Myeong Kim, Jeong-Hyung LeeID53378),Origene,Cat#SR426294 Human BACH1 siRNA,Santa Cruz Biotechnology,Cat#sc-37064 Human NRF2 siRNA,Santa Cruz Biotechnology,Cat#sc-37030 Human FBXO22 siRNA,Santa Cruz Biotechnology,Cat#sc-90142 Human HMOX1 siRNA,Santa Cruz Biotechnology,Cat#sc-35554 Expression

(8) CBX3 promotes multidrug resistance by suppressing ferroptosis in colorectal carcinoma via the CUL3/NRF2/GPX2 axisOncogeneMarch 16, 2025Xiaoming Bai, Tinghong Duan, Jiaofang Shao, Yutong Zhang, Guangyuan Xing, Jie Wang, Xue Liu, Min Wang, Yuanqiao He, Hai Wang, et al.procured from Beijing Tsingke Biotech Co., Ltd. (Beijing, China). SiRNAs, including NRF2 siRNA (h) sc-37030, CUL3 siRNA (h) sc-35130, and GPX2 siRNA (h) sc-62415, were acquired from Santa Cruz Biotechnology (Santa

(9) Protective effects of astaxanthin on particulate matter 2.5‑induced senescence in HaCaT keratinocytes via maintenance of redox homeostasisExperimental and Therapeutic MedicineMay 8, 2024Ao Xuan Zhen, Kyoung Ah Kang, Mei Jing Piao, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Udari Lakmini Herath, Jin Won HyunThermo Fisher Scientific, Inc.) was used to transfect 20 nM siRNA against NRF2 (siNRF2 RNA) (cat. no. sc-37030; Santa Cruz Biotechnology, Inc.) or negative control (siControl RNA) (cat. no. sc-37007; Santa Cruz Biotechnology, Inc

(10) SiONx Coating Regulates Mesenchymal Stem Cell Antioxidant Capacity via Nuclear Erythroid Factor 2 Activity under Toxic Oxidative Stress ConditionsAntioxidants (Basel)February 1, 2024Neelam Ahuja, Kamal Awad, Su Yang, He Dong, Antonios Mikos, Pranesh Aswath, Simon Young, Marco Brotto, Venu Varanasiutilized for the oxidative stress study. We acquired human NRF2 siRNA from Santa Cruz Biotechnology, Inc. (SC-37030), Dallas, TX, USA, to knock down NRF2 (NRF2-KD) in the MSCs. We followed the manufacturer’s protocol

(11) Melatonin targets ferroptosis through bimodal alteration of redox environment and cellular pathways in NAFLD modelBioscience ReportsOctober 31, 2023Moumita Saha, Sanjib Das, Krishnendu Manna, Krishna Das Sahatransfection NRF2 gene expression was knocked down by transfecting 1 × 106 HepG2 cells with siRNA-NRF2 (sc-37030, Santa Cruz, U.S.A.) or siRNA control. Lipofectamine 3000 (Invitrogen, U.S.A.) was used to perform transient

(12) FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male miceNature communicationsSeptember 30, 2023Tong G, Chen Y, Chen X, Fan J, Zhu K, Hu Z, Li S, Zhu J, Feng J, Wu Z, et al.RNA interference L02 cells were transfected with si-FGFR3 (Santa Cruz, sc-29314) or si-NRF2 (Santa Cruz, sc-37030) or siRNA scrambled (negative) control (si-scramble; Santa Cruz, sc-37007) by using Lipofectamine 2000

(13) Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinomaCell communication and signaling : CCSSeptember 18, 2023Bai X, Shao J, Duan T, Liu X, Wang M, Li X, You Q, Zhang Z, Pan J.(Guangzhou, China). SiRNAs were acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA): Nrf2 siRNA (h) sc-37030, Nrf2 siRNA (m) sc-37049, CUL-3 siRNA (h) sc-35130, CUL-3 siRNA (m) sc-35131. The cells (3 × 105) were

(14) Sarmentosin Induces Autophagy-dependent Apoptosis via Activation of Nrf2 in Hepatocellular CarcinomaJournal of clinical and translational hepatologyAugust 28, 2023Jiang Z, Gao L, Liu C, Wang J, Han Y, Pan J.bovine serum (Gibco, #10091148). The transfection solutions of control siRNA, Nrf2 siRNA (Santa Cruz, #sc-37030), and ATG7 siRNA (Santa Cruz, #sc-41447) were prepared according to the manufacturer’s instructions.

(15) Targeted Silencing of NRF2 by rituximab-conjugated nanoparticles increases the sensitivity of chronic lymphoblastic leukemia cells to CyclophosphamideCell communication and signaling : CCSAugust 1, 2023Khodakarami A, Kashani MA, Nazer A, Kheshti AM, Rashidi B, Karpisheh V, Masjedi A, Abolhasani S, Izadi S, Bagherifar R, et al.

(16) Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zincRedox biologyJune 1, 2023Smith MJ, Yang F, Griffiths A, Morrell A, Chapple SJ, Siow RCM, Stewart T, Maret W, Mann GE.

(17) ARE-PROTACs Enable Co-degradation of an Nrf2-MafG HeterodimerJournal of medicinal chemistryMay 11, 2023Ji J, Ma S, Zhu Y, Zhao J, Tong Y, You Q, Jiang Z.

(18) Piperlongumine conjugates induce targeted protein degradationCell chemical biologyFebruary 16, 2023Pei J, Xiao Y, Liu X, Hu W, Sobh A, Yuan Y, Zhou S, Hua N, Mackintosh SG, Zhang X, et al.

(19) Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced NephrotoxicityCancer Res CommunFebruary 1, 2023Jones TM, Espitia CM, Chipollini J, Lee BR, Wertheim JA, Carew JS, Nawrocki ST.

(20) Fresh Medium or L-Cystine as an Effective Nrf2 Inducer for Cytoprotection in Cell CultureCellsJanuary 12, 2023Dai W, Chen QM.80% confluence in 12-well plates were transfected with either control siRNA (sc-37007) or Nrf2 siRNA (sc-37030, Santa Cruz Biotechnology). In each reaction, 50 µL opti-MEM containing 40 pmol siRNA was mixed with

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Nrf2 siRNA (h)

Nrf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Nrf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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