MEK-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMEK-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29396
Gene Namemitogen-activated protein kinase kinase 1
Quantity10 µM
Specieshuman
NCBI Full Gene Namemitogen-activated protein kinase kinase 1
NCBI Gene AliasesCFC3, MAPKK1, MEK1, MEL, MKK1, PRKMK1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) miR‑101 regulates the cell proliferation and apoptosis in diffuse large B‑cell lymphoma by targeting MEK1 via regulation of the ERK/MAPK signaling pathwayOncology reportsJanuary 1, 2019Huang Y, Zou Y, Lin L, Ma X, Zheng R.

(2) CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK PathwayJournal of virologyDecember 15, 2018Wang L, Xie W, Zhang L, Li D, Yu H, Xiong J, Peng J, Qiu J, Sheng H, He X, et al.siRNAs used in this study were purchased from Santa Cruz, including SP1 siRNA (sc-29487), MEK1/2 siRNA (sc-29396 and sc-35905), ERK1/2 siRNA (sc-29307 and sc-35335), and SREBP1 siRNA (sc-36557). Quantitative RT-PCR.

(3) Physiological role of Kvβ2 (AKR6) in murine skeletal muscle growth and regulationActa physiologica (Oxford, England)October 1, 2018Chapalamadugu KC, Tur J, Badole SL, Kukreja RC, Brotto M, Tipparaju SM.

(4) Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like CellsClinical cancer research : an official journal of the American Association for Cancer ResearchOctober 1, 2018Simpkins F, Jang K, Yoon H, Hew KE, Kim M, Azzam DJ, Sun J, Zhao D, Ince TA, Liu W, et al.knockdown on cell cycle Three different antisense oligos to either SRC (sc-29228 for siSRC), or MEK1 (sc-29396 for siMEK1) and scrambled controls from Santa Cruz Biotech (Dallas) were transfected at 70% confluence.

(5) Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoatingPLoS pathogensJanuary 1, 2018Soliman M, Seo JY, Kim DS, Kim JY, Park JG, Alfajaro MM, Baek YB, Cho EH, Kwon J, Choi JS, et al.

(6) SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetesDiabetologiaMarch 1, 2017Qi W, Li Q, Liew CW, Rask-Madsen C, Lockhart SM, Rasmussen LM, Xia Y, Wang X, Khamaisi M, Croce K, et al.experiments. VSMC transfection Small interfering RNA for scramble or Mek1 (also known as Map2k1) (sc-29396; Santa Cruz, Dallas, TX, USA) and Jnk (also known as Mapk8) (no. 6232; Cell Signaling Beverly, MA, USA)

(7) Differential immune mechanism to HIV-1 Tat variants and its regulation by AEA [corrected]Scientific reportsMay 6, 2015Krishnan G, Chatterjee N.were transfected with MKP-1 siRNA (sc-35937), control scrambled MKP-1 siRNA (sc-37007), MEK-1 siRNA (sc-29396) and control scrambled MEK-1 siRNA (sc-44230) (Santa Cruz Biotechnology Inc.). 48 hours after transfection,

(8) Inhibition of tumor growth by U0126 is associated with induction of interferon-γ productionInternational journal of cancerFebruary 15, 2015Ma X, Wang Q, Liu Y, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao RQ, Duan Y, et al.

(9) Anandamide rescues retinal barrier properties in Müller glia through nitric oxide regulationNeuroscienceJanuary 22, 2015Krishnan G, Chatterjee N.

(10) Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicityMolecular and cellular neurosciencesMarch 1, 2014Krishnan G, Chatterjee N.

(11) BRAF activates and physically interacts with PAK to regulate cell motilityEndocrine-related cancerJanuary 1, 2014McCarty SK, Saji M, Zhang X, Knippler CM, Kirschner LS, Fernandez S, Ringel MD.PAK1-specific siRNAs (cat no. sc-29700, Santa Cruz Biotechnology, Inc.), MEK1-specific siRNAs (cat no. sc-29396, Santa Cruz Biotechnology, Inc.), or MEK2 (cat no. sc-35905, Santa Cruz Biotechnology, Inc.) using Lipofectamine

(12) MEK inhibition increases lapatinib sensitivity via modulation of FOXM1Current medicinal chemistryJanuary 1, 2013Gayle SS, Castellino RC, Buss MC, Nahta R.

(13) Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammationGliaNovember 1, 2012Krishnan G, Chatterjee N.

(14) The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced IL-8 production in human bronchial epithelial cellsToxicological sciences : an official journal of the Society of ToxicologyFebruary 1, 2012Lau WK, Chan SC, Law AC, Ip MS, Mak JC.

(15) Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: its implications to therapyPloS oneDecember 14, 2010Nakashima T, Jinnin M, Etoh T, Fukushima S, Masuguchi S, Maruo K, Inoue Y, Ishihara T, Ihn H.

(16) Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathwaysExperimental cell researchFebruary 15, 2010Stapleton CM, Joo JH, Kim YS, Liao G, Panettieri RA Jr, Jetten AM.transfection of siRNAs for human PKCα, βI, and δ (sc-36243, sc-39168, sc-36253, respectively), MEK-1 (cat# sc-29396), MEK-2 (sc-35905), JNK-1 (sc-29380), and JNK-2 (sc-39101) (Santa Cruz Biotechnology, Santa Cruz, CA).

(17) NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathwayThe Journal of biological chemistryJune 13, 2008Joo JH, Jetten AM.

(18) Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress responseCancer researchAugust 15, 2007Joo JH, Liao G, Collins JB, Grissom SF, Jetten AM.

(19) Raf-1 signaling is required for the later stages of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK moduleJournal of cellular physiologyNovember 1, 2006Wang X, Studzinski GP.

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MEK-1 siRNA (h)

MEK-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MEK-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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