HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHIF-1α siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35561
Gene Namehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Quantity10 µM
Specieshuman
NCBI Full Gene Namehypoxia inducible factor 1 subunit alpha
NCBI Gene AliasesHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) GSK3β/HIF-1α signaling-dependent anti-parasite effect of Cynanchi atrati RadixiScienceJanuary 16, 2026Fei-Fei Gao, Guan-Hao Hong, Xin-Cheng Wang, Jia-hui Zeng, Yu-Sun Yun, In-Wook Choi, Jae-Min Yuk, Wei Zhou, Xin-tian Chen, Gang Min Hur, et al.S1 for oligonucleotides used in this paper,This paper,– HIF-1α siRNA,Santa Cruz Biotechnology,Cat#sc-35561 ,, Software and algorithms,Software and algorithms,Software and algorithms ,, ImageJ software,National

(2) HIF‐1 Targeting Intervention Renders Protection From Alzheimer's‐Like Pathology in a Humanized Mice Model of HIV InfectionJournal of Extracellular VesiclesNovember 11, 2025Sudipta Ray, Mohit Kumar, Divya T. Chemparathy, Prasanta K. Dash, Susmita SilMethods 2.1 Reagents The following reagents and antibodies were used in this study: HIF‐1α siRNA (sc‐35561, Santa Cruz Biotechnology, TX, USA), anti‐human HIV‐1 p24 (clone Kal‐1, M0857, Dako, 1:10), HIF‐1α (NB100‐449,

(3) Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolismMolecular oncologySeptember 21, 2025Vaquié AM, Shah DR, Brechbühl EES, McNicholas M, Xu Z, Stockley JH, Morcom L, Gold Diaz D, Girdler GC, Seear RV, et al.with siRNA targeting PHD2 (Santa Cruz Biotechnology, #sc-45537), HIF1a (Santa Cruz Biotechnology, #sc-35561) or control (Santa Cruz Biotechnology, #sc-37007) using Lipofectamine RNAi-MAX Transfection reagent

(4) Ginsenoside 20(S)-Rg3 upregulates SQLE to reprogram cholesterol metabolism of ovarian cancer cellsiScienceAugust 15, 2025Fang He, Yuanyuan Zhou, Jing Fu, ShiXue Chang, Xi Cui, Zhaozu Feng, Le Zhao, Xu LisiRNAs targeting SQLE, FDFT1 (Ribo-Bio Co. Ltd.; Guangzhou, China), HIF-1α (Santa Cruz Biotechnology, sc-35561; Santa Cruz, CA, USA) or negative control siRNA using X-treme GENE transfection reagent (Roche, 04476093001;

(5) Effect of apigetrin in pseudo-SARS-CoV-2-induced inflammatory and pulmonary fibrosis in vitro modelScientific reportsJune 24, 2024Han H, Kim JE, Lee HJ.from Sigma-Aldrich (Cat: 44692, St. Louis, MO, USA). HIF-1α siRNA was purchased from Santa Cruz (Cat: sc-35561, Dallas, TX, USA), and CoCl2 was purchased from Sigma-Aldrich (Cat: C8661, St. Louis, MO, USA). Cell culture

(6) Neuropathogenic role of astrocyte-derived extracellular vesicles in HIV-associated neurocognitive disordersJournal of extracellular vesiclesApril 1, 2024Chemparathy DT, Ray S, Ochs C, Ferguson N, Gawande DY, Dravid SM, Callen S, Sil S, Buch S.HIV‐1 Tat 101 (Immunodiaognistics, Woburn, MA), mutant Tat (ab83352, Abcam, MA, USA), HIF‐1α siRNA (sc‐35561, Santa Cruz Biotechnology, TX, USA), GW4869 (D1692, Sigma‐Aldrich, MO, USA), GFP‐plasmid (13031, Adgene,

(7) An antioxidant response element regulates the HIF1α axis in breast cancer cellsFree Radical Biology and MedicineAugust 1, 2023Sarah E. Lacher, Cara Skon-Hegg, Brian L. Ruis, Jennifer Krznarich, Matthew Slatteryseeding, cells were transfected with 4.9pmol/well of either Control SiRNA-A (sc-37007) or HIF1A siRNA (sc-35561) from Santa Cruz Biotechnology, Inc. using Lipofectamine RNAi MAX (cat# 13778-150, Invitrogen). 48hrs

(8) Functionally enhanced cell spheroids for stem cell therapy: Role of TIMP1 in the survival and therapeutic effectiveness of stem cell spheroidsActa biomaterialiaAugust 1, 2023Choi JK, Chung H, Oh SJ, Kim JW, Kim SH.

(9) Antrodia camphorata and coenzyme Q(0) , a novel quinone derivative of Antrodia camphorata, impede HIF-1α and epithelial-mesenchymal transition/metastasis in human glioblastoma cellsEnvironmental toxicologyJuly 1, 2023Yang HL, Chang YH, Pandey S, Bhat AA, Vadivalagan C, Lin KY, Hseu YC.

(10) HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye diseaseCell reportsJanuary 31, 2023Guo C, Deshpande M, Niu Y, Kachwala I, Flores-Bellver M, Megarity H, Nuse T, Babapoor-Farrokhran S, Ramada M, Sanchez J, et al.in Table S1,This paper,N/A Scrambled siRNA,Santa Cruz,Cat# sc-37007 HIF-1α siRNA,Santa Cruz,Cat# sc-35561 Recombinant DNA,Recombinant DNA,Recombinant DNA Plasmid: pCEFL-EGFP,"Atsuko Sakurai et al., 2010",N/A Plasmid:

(11) Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxiaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismJanuary 1, 2023Mesa-Ciller C, Turiel G, Guajardo-Grence A, Lopez-Rodriguez AB, Egea J, De Bock K, Aragonés J, Urrutia AA.carried out using the following siRNAs: PHD2 siRNA (sc-45537), PHD3 siRNA (sc-45799), HIF1a siRNA (sc-35561) and NDUFA4L2 siRNA (sc-95677), all of them from Santa Cruz Biotechnology (Dallas, TX, USA). As control,

(12) Overactivated NRF2 induces pseudohypoxia in hepatocellular carcinoma by stabilizing HIF-1αFree radical biology & medicineJanuary 1, 2023Zheng J, Kim SJ, Saeidi S, Kim SH, Fang X, Lee YH, Guillen-Quispe YN, Ngo HKC, Kim DH, Kim D, et al.

(13) Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental ValidationJournal of inflammation researchJanuary 1, 2023Su X, Wang G, Zheng S, Ge C, Kong F, Wang C.Cell Transfection Lipofectamine 2000 was used for transient transfection according to the standardized process. HIF-1α siRNA (sc-35561) and control shRNA (sc-37007) was bought from Santa Cruz Biotechnology. The constructed wild-type colon

(14) Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cellsCellular and molecular life sciences : CMLSOctober 2, 2022Lee J, Kim E, Chong K, Ryu SW, Kim C, Choi K, Kim JH, Choi C.(#4851-1, #3091-1, and #5663-1 Daejeon, Republic of Korea) and Santa Cruz Biotechnology (sc-36095, sc-35561, and sc-36312). Scrambled control (sc-37007) was purchased from Santa Cruz Biotechnology. The transient transfection

(15) Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathwayNeoplasia (New York, N.Y.)October 1, 2022Li H, Sun X, Li J, Liu W, Pan G, Mao A, Liu J, Zhang Q, Rao L, Xie X, et al.

(16) Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney InjuryAntioxidants (Basel, Switzerland)September 14, 2022Bondi CD, Rush BM, Hartman HL, Wang J, Al-Bataineh MM, Hughey RP, Tan RJ.with Lipofectamine® RNAiMAX Reagent (#13778-075, Invitrogen, Carlsbad, CA, USA) and HIF-1α siRNA (#sc-35561, Santa Cruz Biotechnology, Dallas, TX, USA) or control siRNA-A (#sc-37007, Santa Cruz Biotechnology)

(17) SPHK/HIF-1α Signaling Pathway Has a Critical Role in Chrysin-Induced Anticancer Activity in Hypoxia-Induced PC-3 CellsCellsSeptember 7, 2022Han H, Lee SO, Xu Y, Kim JE, Lee HJ.Transfection Control (Bioneer, Daejeon, Korea), SPHK-1 (Gene ID: 8877, Bioneer, Daejeon, Korea), and HIF-1α (Cat: SC-35561, Santa Cruz, Dallas, TX, USA) siRNAs were purchased from Bioneer and Santa Cruz. PC-3 cells were plated

(18) GDNF regulates lipid metabolism and glioma growth through RET/ERK/HIF‑1/SREBP‑1International journal of oncologySeptember 1, 2022Yu Z, Li H, Wang M, Luo W, Xue Y.(cat. no. sc-36462; Santa Cruz Biotechnology, Inc.), hypoxia-inducible factor 1 (HIF-1) siRNA (cat. no. sc-35561; Santa Cruz Biotechnology, Inc.), SREBP-1 siRNA (cat. no. sc-36557; Santa Cruz Biotechnology, Inc.)

(19) Staphylococcus aureus Infection Initiates Hypoxia-Mediated Transforming Growth Factor-β1 Upregulation to Trigger OsteomyelitismSystemsAugust 30, 2022Zhang W, Lin Y, Zong Y, Ma X, Jiang C, Shan H, Xia W, Yin L, Wang N, Zhou L, et al.chemiluminescence-based imaging system. Small interfering RNA. The siRNA experiments were performed with HIF-1α siRNA (sc-35561), TGF-β1 siRNA (sc-37192), and scramble control siRNA (sc-37007) following the protocol provided by

(20) Melatonin inhibits NaIO(3)-induced ARPE-19 cell apoptosis via suppression of HIF-1α/BNIP3-LC3B/mitophagy signalingCell & bioscienceAugust 19, 2022Wang K, Chen YS, Chien HW, Chiou HL, Yang SF, Hsieh YH.cytochrome c (sc-13156), β-actin (sc-69879), Lamin B (sc-6216), siRNA-BNIP3 (sc-37451) and siRNA-HIF-1α (sc-35561) for use in Western blotting were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA); antibodies

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HIF-1α siRNA (h)

HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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