HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHIF-1α siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35561
Gene Namehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Quantity10 µM
Specieshuman
NCBI Full Gene Namehypoxia inducible factor 1 subunit alpha
NCBI Gene AliasesHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Hyperglycemia aggravates vitiligo through succinate/SUCNR1-mediated T cell activationJ Clin InvestJune 15, 2026Pan Kang, Yuqian Chang, Tingting Wang, Xiuli Yi, Yinghan Wang, Pengran Du, Jiaxi Chen, Baizhang Li, Shuli Li, Zhongjun Shao, et al.NF-56-EJ40 (HY-130246, MedChemExpress), siRNA for SUCNR1 (sc-62407, Santa Cruz Biotechnology) and HIF-1α (sc-35561, Santa Cruz Biotechnology), and plasmids for HIF-1α (6*His, NM_001530.4, Tsingke). Details for cell culture

(2) GSK3β/HIF-1α signaling-dependent anti-parasite effect of Cynanchi atrati RadixiScienceJanuary 16, 2026Fei-Fei Gao, Guan-Hao Hong, Xin-Cheng Wang, Jia-hui Zeng, Yu-Sun Yun, In-Wook Choi, Jae-Min Yuk, Wei Zhou, Xin-tian Chen, Gang Min Hur, et al.S1 for oligonucleotides used in this paper,This paper,– HIF-1α siRNA,Santa Cruz Biotechnology,Cat#sc-35561 ,, Software and algorithms,Software and algorithms,Software and algorithms ,, ImageJ software,National

(3) HIF‐1 Targeting Intervention Renders Protection From Alzheimer's‐Like Pathology in a Humanized Mice Model of HIV InfectionJournal of Extracellular VesiclesNovember 11, 2025Sudipta Ray, Mohit Kumar, Divya T. Chemparathy, Prasanta K. Dash, Susmita SilMethods 2.1 Reagents The following reagents and antibodies were used in this study: HIF‐1α siRNA (sc‐35561, Santa Cruz Biotechnology, TX, USA), anti‐human HIV‐1 p24 (clone Kal‐1, M0857, Dako, 1:10), HIF‐1α (NB100‐449,

(4) Ginsenoside 20(S)-Rg3 upregulates SQLE to reprogram cholesterol metabolism of ovarian cancer cellsiScienceAugust 15, 2025Fang He, Yuanyuan Zhou, Jing Fu, ShiXue Chang, Xi Cui, Zhaozu Feng, Le Zhao, Xu LisiRNAs targeting SQLE, FDFT1 (Ribo-Bio Co. Ltd.; Guangzhou, China), HIF-1α (Santa Cruz Biotechnology, sc-35561; Santa Cruz, CA, USA) or negative control siRNA using X-treme GENE transfection reagent (Roche, 04476093001;

(5) An antioxidant response element regulates the HIF1α axis in breast cancer cellsFree Radical Biology and MedicineAugust 1, 2023Sarah E. Lacher, Cara Skon-Hegg, Brian L. Ruis, Jennifer Krznarich, Matthew Slatteryseeding, cells were transfected with 4.9pmol/well of either Control SiRNA-A (sc-37007) or HIF1A siRNA (sc-35561) from Santa Cruz Biotechnology, Inc. using Lipofectamine RNAi MAX (cat# 13778-150, Invitrogen). 48hrs

(6) Functionally enhanced cell spheroids for stem cell therapy: Role of TIMP1 in the survival and therapeutic effectiveness of stem cell spheroidsActa biomaterialiaAugust 1, 2023Choi JK, Chung H, Oh SJ, Kim JW, Kim SH.

(7) Antrodia camphorata and coenzyme Q(0) , a novel quinone derivative of Antrodia camphorata, impede HIF-1α and epithelial-mesenchymal transition/metastasis in human glioblastoma cellsEnvironmental toxicologyJuly 1, 2023Yang HL, Chang YH, Pandey S, Bhat AA, Vadivalagan C, Lin KY, Hseu YC.

(8) HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye diseaseCell reportsJanuary 31, 2023Guo C, Deshpande M, Niu Y, Kachwala I, Flores-Bellver M, Megarity H, Nuse T, Babapoor-Farrokhran S, Ramada M, Sanchez J, et al.in Table S1,This paper,N/A Scrambled siRNA,Santa Cruz,Cat# sc-37007 HIF-1α siRNA,Santa Cruz,Cat# sc-35561 Recombinant DNA,Recombinant DNA,Recombinant DNA Plasmid: pCEFL-EGFP,"Atsuko Sakurai et al., 2010",N/A Plasmid:

(9) Overactivated NRF2 induces pseudohypoxia in hepatocellular carcinoma by stabilizing HIF-1αFree radical biology & medicineJanuary 1, 2023Zheng J, Kim SJ, Saeidi S, Kim SH, Fang X, Lee YH, Guillen-Quispe YN, Ngo HKC, Kim DH, Kim D, et al.

(10) Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxiaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismJanuary 1, 2023Mesa-Ciller C, Turiel G, Guajardo-Grence A, Lopez-Rodriguez AB, Egea J, De Bock K, Aragonés J, Urrutia AA.carried out using the following siRNAs: PHD2 siRNA (sc-45537), PHD3 siRNA (sc-45799), HIF1a siRNA (sc-35561) and NDUFA4L2 siRNA (sc-95677), all of them from Santa Cruz Biotechnology (Dallas, TX, USA). As control,

(11) Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental ValidationJournal of inflammation researchJanuary 1, 2023Su X, Wang G, Zheng S, Ge C, Kong F, Wang C.Cell Transfection Lipofectamine 2000 was used for transient transfection according to the standardized process. HIF-1α siRNA (sc-35561) and control shRNA (sc-37007) was bought from Santa Cruz Biotechnology. The constructed wild-type colon

(12) Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cellsCellular and molecular life sciences : CMLSOctober 2, 2022Lee J, Kim E, Chong K, Ryu SW, Kim C, Choi K, Kim JH, Choi C.(#4851-1, #3091-1, and #5663-1 Daejeon, Republic of Korea) and Santa Cruz Biotechnology (sc-36095, sc-35561, and sc-36312). Scrambled control (sc-37007) was purchased from Santa Cruz Biotechnology. The transient transfection

(13) Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathwayNeoplasia (New York, N.Y.)October 1, 2022Li H, Sun X, Li J, Liu W, Pan G, Mao A, Liu J, Zhang Q, Rao L, Xie X, et al.

(14) Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney InjuryAntioxidants (Basel, Switzerland)September 14, 2022Bondi CD, Rush BM, Hartman HL, Wang J, Al-Bataineh MM, Hughey RP, Tan RJ.with Lipofectamine® RNAiMAX Reagent (#13778-075, Invitrogen, Carlsbad, CA, USA) and HIF-1α siRNA (#sc-35561, Santa Cruz Biotechnology, Dallas, TX, USA) or control siRNA-A (#sc-37007, Santa Cruz Biotechnology)

(15) GDNF regulates lipid metabolism and glioma growth through RET/ERK/HIF‑1/SREBP‑1International journal of oncologySeptember 1, 2022Yu Z, Li H, Wang M, Luo W, Xue Y.(cat. no. sc-36462; Santa Cruz Biotechnology, Inc.), hypoxia-inducible factor 1 (HIF-1) siRNA (cat. no. sc-35561; Santa Cruz Biotechnology, Inc.), SREBP-1 siRNA (cat. no. sc-36557; Santa Cruz Biotechnology, Inc.)

(16) Staphylococcus aureus Infection Initiates Hypoxia-Mediated Transforming Growth Factor-β1 Upregulation to Trigger OsteomyelitismSystemsAugust 30, 2022Zhang W, Lin Y, Zong Y, Ma X, Jiang C, Shan H, Xia W, Yin L, Wang N, Zhou L, et al.chemiluminescence-based imaging system. Small interfering RNA. The siRNA experiments were performed with HIF-1α siRNA (sc-35561), TGF-β1 siRNA (sc-37192), and scramble control siRNA (sc-37007) following the protocol provided by

(17) HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathwayBritish journal of cancerAugust 1, 2022Tang K, Toyozumi T, Murakami K, Sakata H, Kano M, Endo S, Matsumoto Y, Suito H, Takahashi M, Sekino N, et al.

(18) A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and AngiogenesisCancer Res CommunJuly 12, 2022Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, Jaya Padmanabhan, Domenico Coppola, Srikumar Chellappanrespectively. siRNAs For TAZ (sc-45232), MST1 (sc-39249), MST2 (sc-39247), LATS2 (sc-37444), HIF1α (sc-35561), PHD2 (sc-45537), PHD3 (sc-45799), TEAD2 (sc-45232), and TEAD4 (sc-96187) were purchased from Santa Cruz Biotechnology

(19) A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and AngiogenesisCancer Res CommunJuly 1, 2022Bora-Singhal N, Saha B, Mohankumar D, Padmanabhan J, Coppola D, Chellappan S.respectively. siRNAs For TAZ (sc-45232), MST1 (sc-39249), MST2 (sc-39247), LATS2 (sc-37444), HIF1α (sc-35561), PHD2 (sc-45537), PHD3 (sc-45799), TEAD2 (sc-45232), and TEAD4 (sc-96187) were purchased from Santa Cruz Biotechnology

(20) Galectin-1 activates carbonic anhydrase IX and modulates glioma metabolismCell death & diseaseJune 30, 2022Guda MR, Tsung AJ, Asuthkar S, Velpula KK.reoxygenation period, cells were provided with a fresh medium. In another experiment, we used HIF-1α siRNA (sc35561, Santa Cruz Biotechnology) to transfect both GSC20 and GSC33 cells. After 48 h of transfection, lysates

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HIF-1α siRNA (h)

HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HIF-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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