BRD4 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemBRD4 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43639
Quantity10 µM
Gene Namebromodomain containing 4
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene Namebromodomain containing 4
NCBI Gene AliasesCAP, FSHRG4, HUNK1, HUNKI, MCAP

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1GastroenterologyJuly 1, 2023Kang JH, Splinter PL, Trussoni CE, Pirius NE, Gores GJ, LaRusso NF, O'Hara SP.knockdown of BRD2 and BRD4 NHCsen were incubated with siRNAs (60 nM) to BRD2 (sc-60282) and BRD4 (sc-43639) or non-targeting siRNAs (sc-37007; Santa Cruz). Briefly, 2.5 × 105 cells were transfected with Lipofectamine

(2) Inhibition of bromodomain-containing protein 4 enhances the migration of esophageal squamous cell carcinoma cells by inducing cell autophagyWorld journal of gastrointestinal oncologyDecember 15, 2022Yang WQ, Liang R, Gao MQ, Liu YZ, Qi B, Zhao BS.BRD4 small interfering RNA (siBRD4) and control siRNA were purchased from Santa Cruz Biotechnology (sc-43639, Carlsbad, CA, United States). Cells cultured in a 6-well plate at 60% density were transfected with

(3) OTX015 Epi-Drug Exerts Antitumor Effects in Ovarian Cancer Cells by Blocking GNL3-Mediated Radioresistance Mechanisms: Cellular, Molecular and Computational EvidenceCancersMarch 25, 2021Megiorni F, Camero S, Pontecorvi P, Camicia L, Marampon F, Ceccarelli S, Anastasiadou E, Bernabò N, Perniola G, Pizzuti A, et al.plates) were transfected with a pool of small interfering RNAs (siRNAs) against human BRD4 (si-BRD4, sc-43639 by Santa Cruz Biotechnology), GNL3 (si-GNL3, sc-45830 by Santa Cruz Biotechnology), or siRNA negative

(4) The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signalingOncotargetAugust 18, 2020Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, Wahlestedt C, El-Rifai W, Robbins DJ, Capobianco AJ.

(5) BET inhibition therapy counteracts cancer cell survival, clonogenic potential and radioresistance mechanisms in rhabdomyosarcoma cellsCancer lettersJune 1, 2020Camero S, Camicia L, Marampon F, Ceccarelli S, Shukla R, Mannarino O, Pizer B, Schiavetti A, Pizzuti A, Tombolini V, et al.

(6) BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1Cancer researchJune 1, 2020Zong D, Gu J, Cavalcante GC, Yao W, Zhang G, Wang S, Owonikoko TK, He X, Sun SY.

(7) miRNA-302e attenuates inflammation in infantile pneumonia though the RelA/BRD4/NF-κB signaling pathwayInternational journal of molecular medicineJuly 1, 2019Li S, Cui W, Song Q, Zhou Y, Li J.interfering (si)-RelA (cat. no. s11917; Ambion; Thermo Fisher Scientific, Inc.), si-BRD4 (cat. no. sc-43639) and si-NF-κB (cat. no. sc-44212) were purchased from Santa Cruz Biotechnology, Inc. miRNA-302e (5′-UAAGUGCUUCCAUGUUUUGGUGA-3′),

(8) Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stressRedox biologyJune 1, 2019Liu H, Wang L, Weng X, Chen H, Du Y, Diao C, Chen Z, Liu X.

(9) MicroRNA-200a suppresses prostate cancer progression through BRD4/AR signaling pathwayCancer medicineApril 1, 2019Guan H, You Z, Wang C, Fang F, Peng R, Mao L, Xu B, Chen M.

(10) BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5Cancer researchMarch 15, 2019Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L.scrambled, CHOP (5’-GCACAGCUAGCUGAAGAGAdTdT-3’), DR5 (5’-AAGACCCUUGUGCUCGUUGUCdTdT-3’) (Dharmacon), BRD4 (sc-43639), or SPOP (sc-63056) siRNA (Santa Cruz Biotechnology). mRNA sequencing (RNA-Seq) Total RNA was prepared

(11) Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expressionJournal of orthopaedic surgery and researchFebruary 20, 2019Dai J, Zhou S, Ge Q, Qin J, Li J, Ju H, Cao Y, Zheng M, Li C, Gao X, et al.

(12) Long non-coding RNA LINC00346 promotes pancreatic cancer growth and gemcitabine resistance by sponging miR-188-3p to derepress BRD4 expressionJournal of experimental & clinical cancer research : CRFebruary 6, 2019Shi W, Zhang C, Ning Z, Hua Y, Li Y, Chen L, Liu L, Chen Z, Meng Z.

(13) Dual PI3K-BRD4 Inhibitor SF1126 Inhibits Colorectal Cancer Cell Growth in Vitro and in VivoCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2019Qin AC, Li Y, Zhou LN, Xing CG, Lu XS.

(14) BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic SyndromesFrontiers in oncologyJanuary 1, 2019Pericole FV, Lazarini M, de Paiva LB, Duarte ADSS, Vieira Ferro KP, Niemann FS, Roversi FM, Olalla Saad ST.

(15) Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate CancerMolecular cancer therapeuticsDecember 1, 2018Nerlakanti N, Yao J, Nguyen DT, Patel AK, Eroshkin AM, Lawrence HR, Ayaz M, Kuenzi BM, Agarwal N, Chen Y, et al.

(16) microRNA-608 inhibits human hepatocellular carcinoma cell proliferation via targeting the BET family protein BRD4Biochemical and biophysical research communicationsJuly 2, 2018He L, Meng D, Zhang SH, Zhang Y, Deng Z, Kong LB.

(17) BRD4 inhibitor JQ1 inhibits and reverses mechanical injury-induced corneal scarringCell death discoveryJanuary 1, 2018Qu M, Zhang X, Hu X, Dong M, Pan X, Bian J, Zhou Q.cultured as previously described43. HTKs (2 × 105 cells) were seeded and transfected with 1 µg BRD4 siRNA (sc-43639; Santa Cruz Biotechnology, Santa Cruz, CA, USA) or control siRNA duplex (sc-37007; Santa Cruz Biotechnology).

(18) Bromodomain-Containing Protein 4 (BRD4) Inhibition Sensitizes Palomid 529-Induced Anti-Renal Cell Carcinoma Cell Activity in Vitro and in VivoCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Xing ZY, Wang Y, Cheng L, Chen J, He XZ, Xing W.

(19) Transcription Elongation Factor P-TEFb Is Involved in IL-17F Signaling in Airway Smooth Muscle CellsInternational archives of allergy and immunologyJanuary 1, 2018Nakajima M, Kawaguchi M, Matsuyama M, Ota K, Fujita J, Matsukura S, Huang SK, Morishima Y, Ishii Y, Satoh H, et al.

(20) Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expressionRedox biologyApril 1, 2017Zhou B, Mu J, Gong Y, Lu C, Zhao Y, He T, Qin Z.

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BRD4 siRNA (h)

BRD4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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BRD4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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