Clathrin HC siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemClathrin HC siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35067
Quantity10 µM
TypesiRNA/dsRNA
Gene Nameclathrin, heavy chain (Hc)
NCBI Gene AliasesCHC, CHC17, CLH-17, CLTCL2, Hc, MRD56
NCBI Full Gene Nameclathrin heavy chain
Specieshuman

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Miriplatin-loaded liposome, as a novel mitophagy inducer, suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replicationActa Pharmaceutica Sinica BNovember 1, 2023Xiaowei Wang, Mengyan Wang, Meilian Cai, Rongguang Shao, Guimin Xia, Wuli Zhaopurchased from Sino Biological (Beijing, China). Small interfering RNA (siRNA): clathrin HC siRNA (h) (sc-35067) and caveolin-1 siRNA (h) (sc-29241) were purchased from Santa Cruz (California, USA). si-h-POLG_101

(2) A universal method to analyze cellular internalization mechanisms via endocytosis without non-specific cross-effectsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2023Itagaki M, Nasu Y, Sugiyama C, Nakase I, Kamei N.

(3) Transport mechanism and subcellular localization of a polysaccharide from Cucurbia Moschata across Caco-2 cells modelInternational journal of biological macromoleculesJuly 1, 2021Li F, Wei Y, Zhao J, Yu G, Huang L, Li Q.

(4) Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent FashionFrontiers in microbiologyJanuary 1, 2021Shi R, Hou L, Wei L, Quan R, Zhou B, Jiang H, Wang J, Zhu S, Song J, Wang D, et al.(Invitrogen, 13778150) according to the manufacturer’s instructions. The siRNAs targeting CLTC (siCLTC, sc-35067), caveolin-1 (siCav1, sc-29241), Rab5 (siRab5, sc-36344), Rab7 (siRab7, sc-29460), and siRNA with a

(5) Avian Flavivirus Enters BHK-21 Cells by a Low pH-Dependent Endosomal PathwayVirusesNovember 30, 2019Baloch AS, Liu C, Liang X, Liu Y, Chen J, Cao R, Zhou B.Japan. 2.6. siRNA Transfections Small interference RNAs siV-ATPase (sc-36787), siCHC Clathrin heavy chain (sc-35067), and negative-control siRNA (sc-37007) all were purchased from Santa Cruz Biotechnology, Inc. Before

(6) Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutationPLoS pathogensJuly 1, 2019Wang C, Puerta-Guardo H, Biering SB, Glasner DR, Tran EB, Patana M, Gomberg TA, Malvar C, Lo NTN, Espinosa DA, et al.from Santa Cruz Biotechnology was used. In brief, Control siRNA-A (sc-37007), Clathrin HC siRNA (h) (sc-35067), Dynamin I/II (sc-43736), and caveolin-1 siRNA (h) (sc-29241) were resuspended in siRNA Dilution Buffer

(7) Bacterial Clearance Is Enhanced by α2,3- and α2,6-Sialyllactose via Receptor-Mediated Endocytosis and PhagocytosisInfection and immunityJanuary 1, 2019Kim J, Kim YJ, Kim JW.HiPerFect reagent (Qiagen, Hilden, Germany) according to the manufacturer’s protocol. Clathrin siRNA (sc-35067), Myd88 siRNA (sc-35986), and TRIF siRNA (sc-106845) were obtained from Santa Cruz Biotechnology. RNA

(8) 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) Rapidly Resolves LPS-Induced Acute Lung Injury Through the Effective Control of Neutrophil RecruitmentFrontiers in immunologyJanuary 1, 2019Lee HR, Shin SH, Kim JH, Sohn KY, Yoon SY, Kim JW.(sc-44900), glycosylphosphatidylinositol high density binding protein 1 (GPI-HBP1) (sc-145686), clathrin (sc-35067), and caveolin-1 (sc-29241) were purchased from Santa Cruz Biotechnology. Scramble siRNA (sc-37007)

(9) Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral ActivityJournal of virologyDecember 15, 2018Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, Shen F, Shi B, Liu J, Peng L, et al.

(10) Porcine sapovirus Cowden strain enters LLC-PK cells via clathrin- and cholesterol-dependent endocytosis with the requirement of dynamin IIVeterinary researchSeptember 17, 2018Soliman M, Kim DS, Kim C, Seo JY, Kim JY, Park JG, Alfajaro MM, Baek YB, Cho EH, Park SI, et al.

(11) Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cellsThe Journal of cell biologyAugust 6, 2018Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, et al.5′-UUUCUUUAUAGUUUGAGAGCCUCUG-3′. siRNA against caveolin 1 (sc-29241), siRNA against clathrin–heavy chain (HC; sc-35067), and scrambled siRNA (sc-37007) were purchased from Santa Cruz Biotechnology. Antibodies The following

(12) Rab5, Rab7, and Rab11 Are Required for Caveola-Dependent Endocytosis of Classical Swine Fever Virus in Porcine Alveolar MacrophagesJournal of virologyAugust 1, 2018Zhang YN, Liu YY, Xiao FC, Liu CC, Liang XD, Chen J, Zhou J, Baloch AS, Kan L, Zhou B, et al.

(13) Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptorsScientific reportsMarch 5, 2018Takahashi T, Kulkarni NN, Lee EY, Zhang LJ, Wong GCL, Gallo RL.

(14) The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case StudyCell chemical biologyJanuary 18, 2018Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J, et al.

(15) Rab5 and Rab11 Are Required for Clathrin-Dependent Endocytosis of Japanese Encephalitis Virus in BHK-21 CellsJournal of virologyOctober 1, 2017Liu CC, Zhang YN, Li ZY, Hou JX, Zhou J, Kan L, Zhou B, Chen PY.the manufacturer’s instructions. siRNA duplexes used in the study are as follows: clathrin heavy chain (sc-35067), caveolin-1 (sc-29241), V-ATPase B1 (sc-36787), siRab5 (sc-36344), siRab7 (sc-29460), siRab9 (sc-44065),

(16) Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanismsBioorganic & medicinal chemistryJanuary 1, 2017Ugarte-Uribe B, Grijalvo S, Pertíñez SN, Busto JV, Martín C, Alagia A, Goñi FM, Eritja R, Alkorta I.

(17) Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interactionCellular signallingDecember 1, 2014Allonby O, El Zawily AM, Freywald T, Mousseau DD, Chlan J, Anderson D, Benmerah A, Sidhu V, Babu M, DeCoteau J, et al.

(18) Herpes simplex virus internalization into epithelial cells requires Na+/H+ exchangers and p21-activated kinases but neither clathrin- nor caveolin-mediated endocytosisJournal of virologyNovember 1, 2014Devadas D, Koithan T, Diestel R, Prank U, Sodeik B, Döhner K.Qiagen (Hilden, Germany); that against clathrin heavy chain (CHC) was from Santa Cruz Biotechnology (sc-35067; Heidelberg, Germany); and Silencer GFP siRNA was from Ambion (AM4626; Darmstadt, Germany). HeLaS3 or

(19) Differential requirements of arrestin-3 and clathrin for ligand-dependent and -independent internalization of human G protein-coupled receptor 40Cellular signallingNovember 1, 2014Qian J, Wu C, Chen X, Li X, Ying G, Jin L, Ma Q, Li G, Shi Y, Zhang G, et al.

(20) A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signalsThe Journal of investigative dermatologyApril 1, 2014Zhu J, Lin F, Brown DA, Clark RAF.(TUNEL reaction mixture) was purchased from Roche Diagnostics (Indianapolis, IN). SiRNA for CHC KD (sc-35067) was purchased from Santa Cruz Biotechnology (Dallas, TX). Allstar negative control siRNA and Hiperfect

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