PLC γ1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPLC γ1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29452
Gene Namephospholipase C, gamma 1
Quantity10 µM
Specieshuman
NCBI Full Gene Namephospholipase C gamma 1
NCBI Gene AliasesNCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic Colorectal CancerClinical cancer research : an official journal of the American Association for Cancer ResearchMarch 15, 2022Cruz-Duarte R, Rebelo de Almeida C, Negrão M, Fernandes A, Borralho P, Sobral D, Gallego-Paez LM, Machado D, Gramaça J, Vílchez J, et al.knockdown, CACO-2 cells were infected with PLCG1 shRNA lentiviral particles and scrambled control (#sc-29452 and #sc-108080; Santa Cruz Biotechnology). Selection of stable clones started 2 days after infection

(2) Phospholipase C controls chloride-dependent short-circuit current in human bronchial epithelial cellsAmerican journal of physiology. Lung cellular and molecular physiologyFebruary 1, 2021Grebert C, Becq F, Vandebrouck C.

(3) OSBP-Related Protein 5L Maintains Intracellular IP₃/Ca²⁺ Signaling and Proliferation in T Cells by Facilitating PIP₂ HydrolysisJournal of immunology (Baltimore, Md. : 1950)March 1, 2020Xu M, Zhu B, Cao X, Li S, Li D, Zhou H, Olkkonen VM, Zhong W, Xu J, Yan D.sequence was 59-CCCTGCCCAGCAGCTACCTGATCTT-39. The siPLCg1 was purchased from Santa Cruz Biotechnology (sc-29452). Quantitative RT-PCR Total RNA was isolated with TRIzol Reagent (Invitrogen) according to the manufacturer’s

(4) BDNF activates TrkB/PLCγ1 signaling pathway to promote proliferation and invasion of ovarian cancer cells through inhibition of apoptosisEuropean review for medical and pharmacological sciencesJune 1, 2019Xu Y, Jiang WG, Wang HC, Martin T, Zeng YX, Zhang J, Qi YS.

(5) TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3pNature communicationsOctober 16, 2017Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, et al.

(6) Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxationThe Journal of biological chemistryJanuary 2, 2015Cho YL, Hur SM, Kim JY, Kim JH, Lee DK, Choe J, Won MH, Ha KS, Jeoung D, Han S, et al.

(7) Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesisThe Journal of clinical investigationSeptember 1, 2014de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, et al.

(8) Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasionNature structural & molecular biologyFebruary 1, 2014Timsah Z, Ahmed Z, Lin CC, Melo FA, Stagg LJ, Leonard PG, Jeyabal P, Berrout J, O'Neil RG, Bogdanov M, et al.

(9) PKCε acts as negative allosteric modulator of EGF receptor signallingCellular signallingFebruary 1, 2011Weisheit S, Schäfer C, Mertens C, Berndt A, Liebmann C.

(10) Exchange protein directly activated by cyclic AMP increases melanoma cell migration by a Ca2+-dependent mechanismCancer researchJuly 1, 2010Baljinnyam E, De Lorenzo MS, Xie LH, Iwatsubo M, Chen S, Goydos JS, Nowycky MC, Iwatsubo K.

(11) Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-SCancer researchFebruary 1, 2010Hong J, Behar J, Wands J, Resnick M, Wang LJ, Delellis RA, Lambeth D, Cao W.

(12) Distinct role of PLCbeta3 in VEGF-mediated directional migration and vascular sproutingJournal of cell scienceApril 1, 2009Bhattacharya R, Kwon J, Li X, Wang E, Patra S, Bida JP, Bajzer Z, Claesson-Welsh L, Mukhopadhyay D.times. siRNA transfection HUVECs were transfected with control scrambled (sc37007), PLCβ3 (sc36272) or PLCγ1 (sc29452) siRNA obtained from Santa Cruz Biotechnology (Santa Cruz, CA) using Oligofectamine reagent in Opti-MEM

(13) PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signalsAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2008Han S, Ritzenthaler JD, Zheng Y, Roman J.

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PLC γ1 siRNA (h)

PLC γ1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PLC γ1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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