Nrf2 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNrf2 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37049
Gene Namenuclear factor (erythroid-derived 2)-like 2
Quantity10 µM
Speciesmouse
NCBI Full Gene Namenuclear factor, erythroid derived 2, like 2
NCBI Gene AliasesNrf2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Administration with carnosic acid alleviates the development of osteoarthritis by attenuating macrophage polarization-mediated inflammation and cartilage oxidative damage and degradation via regulating Nrf2/NF-kB axisFrontiers in ImmunologyFebruary 10, 2026Yang Yang, Wenwen Ping, Jin Xu, Rong Yangscrambled siRNAs were defined as the negative control (si-NC). The siRNA sequences targeting Nrf2 (cat. sc-37049) and si-NC (cat. sc- 37007) were synthesized from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA, USA).

(2) Targeting of a novel interplay between MET tyrosine kinase and NRF2 enhances sensitivity to Paclitaxel in triple negative breast cancerJournal of Experimental & Clinical Cancer ResearchJanuary 20, 2026Irene Taddei, Claudia Cirotti, Fabienne Lamballe, Olivier Castellanet, Flavio Maina, Vanessa Medici, Fabrizio Fierro, Giacomo Corleone, Francesca De Nicola, Maurizio Fanciulli, et al.human MET siRNA (Santa Cruz Biotechnology; sc-35924, sc-29397) or NRF2 siRNA (Santa Cruz Biotechnology; sc-37049) according to the manufacturer’s instructions. For transient transfection, MGT-13 cells were seeded

(3) Lysionotin attenuates bleomycin-induced pulmonary fibrosis by activating AMPK/Nrf2 pathwaySci RepAugust 25, 2025Xiaohua Zhang, Dayan Xiong, Lang Deng, Rui Qian, Siyuan Tang, Wei Liu, Yin Li, Lang Liu, Weixi Xie, Miao Linwere transfected with siRNA (control siRNA or AMPK siRNA or Nrf2 siRNA, Cat# sc-37007, sc-29674, Cat# sc-37049, Santa Cruz, USA) using Lipofectamine 3000(Cat# L3000150, Invitrogen, USA) according to the manufacturer’s

(4) Proteomic analysis reveals inhibition of mevalonate and glycolysis pathways in hepatocytes by 27-hydroxycholesterolBiochemical JournalAugust 6, 2025Wan-Seog Shim, Seulah Lee, Bakhovuddin Azamov, Chanhee Lee, Yeowon Kang, Kwang Min Lee, Changwan Hong, Sang-Mo Kwon, Koanhoi Kim, Dongjun Lee, et al.experiment AML12 cells were transfected with Nrf2 small-interfering RNA (Santa Cruz Biotechnology, Inc.; cat. no. sc-37049) or negative control siRNA (Bioneer, Inc.; cat. no. SN-1002) using Lipofectamine 2000 (Invitrogen, Carlsbad,

(5) Transcriptomic signatures of oxytosis/ferroptosis are enriched in Alzheimer's diseaseBMC BiolMay 14, 2025Antonio Currais, Kayla Sanchez, David Soriano-Castell, Nawab John Dar, K. Garrett Evensen, Salvador Soriano, Pamela Mahercells were transfected with siRNA against Atf4 (Santa Cruz, sc-351113, 17 pmol) or Nrf2 (Santa Cruz, sc-37049, 17 pmol), using lipofectamine (RNAiMAX, ThermoFisher) as the transfection reagent and Opti-MEM (GibcoTM)

(6) ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammationNeoplasiaFebruary 4, 2025Li-Quan Huang, Ting-Xuan Yan, Bao-Sheng Wang, Hao Li, Nai-Bao Zhouinterfering RNAs (siRNAs) targeting ZC3H15 (si-ZC3H15, #sc146711, Santa Cruz, USA), Nrf2 (si-Nrf2, #sc37049, Santa Cruz, USA) and the control siRNAs (sequences: 5’-AATTCTCCGAACGTGTCACGT-3’, GenePharma Co., Ltd.,

(7) Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathwayChin MedJanuary 15, 2025Hui Zhang, Yan Wang, Shenghua Wang, Xiaomei Xue, Kai Huang, Dunfeng Xu, Lai Jiang, Siyuan Li, Yunqian Zhangcollected for the next experiment. siRNA transfection To inhibit the gene expression, Nrf2 siRNA (cat.no. sc-37049, Santa Cruz, USA) was transfected into RAW264.7 cells using Xfect siRNA transfection reagent (Takara

(8) Trimethylamine N-Oxide Improves Exercise Performance by Reducing Oxidative Stress through Activation of the Nrf2 Signaling PathwayMoleculesFebruary 6, 2024Hong Zou, Yu Zhou, Lijing Gong, Caihua Huang, Xi Liu, Ruohan Lu, Jingjing Yu, Zhenxing Kong, Yimin Zhang, Donghai Lin(Nanjing, China). Nrf2 small interfering RNA (siRNA) was provided by Santa Cruz Biotechnology, Inc. (sc-37049, Dallas, TX, USA). Lipofectamine 2000 (lip2000) for transfection was purchased from Thermo Fisher Scientific

(9) Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinomaCell communication and signaling : CCSSeptember 18, 2023Bai X, Shao J, Duan T, Liu X, Wang M, Li X, You Q, Zhang Z, Pan J.acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA): Nrf2 siRNA (h) sc-37030, Nrf2 siRNA (m) sc-37049, CUL-3 siRNA (h) sc-35130, CUL-3 siRNA (m) sc-35131. The cells (3 × 105) were seeded and grown in 6-well

(10) Methylmercury (MeHg) transcriptionally regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) in Hepa-1c1c7 cellsCurrent Research in ToxicologySeptember 17, 2023Mohammed A. Alqahtani, Mahmoud A. El-Ghiaty, Sara R. El-Mahrouk, Ayman O.S. El-KadiMouse monoclonal anti-NQO1 (sc-32793), anti-NRF2 (sc-365949), anti-LAMIN B1 (sc-377000), Nrf2 siRNA (sc-37049), siRNA transfection medium (sc-36868), siRNA transfection reagent (sc-29528) control siRNA-A (sc-37007)

(11) Macrophage PTEN controls STING-induced inflammation and necroptosis through NICD/NRF2 signaling in APAP-induced liver injuryCell communication and signaling : CCSJune 27, 2023Yang T, Qu X, Zhao J, Wang X, Wang Q, Dai J, Zhu C, Li J, Jiang L.injected with the nonspecific (NS) control siRNA or Nrf2 siRNA (2 mg/kg; Santa Cruz Biotechnology (SC), sc-37049) mixed with mannose-conjugated polymers (Polyplus transfection™, Illkirch, France) at a ratio via the

(12) Targeting KAT2A inhibits inflammatory macrophage activation and rheumatoid arthritis through epigenetic and metabolic reprogrammingMedComm (2020)June 1, 2023Zhang Y, Gao Y, Ding Y, Jiang Y, Chen H, Zhan Z, Liu X.(L‐040665‐01‐0010) and nontargeting control (D‐001810‐10‐05) were from Dharmacon. The siRNAs targeting Nrf2 (sc‐37049) and control siRNA (sc‐37007) were from Santa Cruz Biotechnology. Macrophages were transfected with

(13) Autophagy Plays a Crucial Role in Ameloblast DifferentiationJournal of Dental ResearchMay 30, 2023C. Iwaya, A. Suzuki, J. Shim, C. G. Ambrose, J. IwataSanta Cruz Biotechnology), according to the manufacturer’s protocol. Mouse Nrf2/Nfe2l2 siRNA (NM-010902; mapping to 2C3, Sc-37049; Santa Cruz Biotechnology) or the negative control siRNA (sc-37007; Santa Cruz Biotechnology) were transfected

(14) Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic StabilityAntioxidants (Basel, Switzerland)February 13, 2023Mak KK, Shiming Z, Sakirolla R, Balijepalli MK, Dinkova-Kostova AT, Epemolu O, Mohd Z, Pichika MR.

(15) Briarane-type diterpenoids, the inhibitors of osteoclast formation by interrupting Keap1-Nrf2 interaction and activating Nrf2 pathwayEuropean journal of medicinal chemistryJanuary 15, 2023Qi X, Zhang X, Meng J, Wu J, Cheng W, Huang J, Lin W.

(16) PM2.5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62-KEAP1-NRF2 activation in neuronal cellsEcotoxicology and environmental safetyDecember 15, 2022Wei M, Bao G, Li S, Yang Z, Cheng C, Le W.

(17) Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 CellsCellsNovember 14, 2022Kim EN, Trang NM, Kang H, Kim KH, Jeong GS.

(18) Structural Requirements for the Neuroprotective and Anti-Inflammatory Activities of the Flavanone SterubinAntioxidants (Basel, Switzerland)November 7, 2022Liang Z, Maher P.transfection, BV2 cells were plated in 60 mm dishes at 5 × 105 cells/dish and 20 pmol Nrf2 siRNA (#sc-37049) from Santa Cruz Biotechnology or control siRNA (#1027280) from Qiagen (Hilden, Germany) were used along

(19) High Cholesterol-Induced Bone Loss Is Attenuated by Arctiin via an Action in OsteoclastsNutrientsOctober 25, 2022Li G, Park JN, Park HJ, Suh JH, Choi HS.

(20) Evogliptin Directly Inhibits Inflammatory and Fibrotic Signaling in Isolated Liver CellsInternational journal of molecular sciencesOctober 1, 2022Seo HY, Lee SH, Han E, Hwang JS, Han S, Kim MK, Jang BK.

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Nrf2 siRNA (m)

Nrf2 siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Nrf2 siRNA (m) from Santa Cruz Biotechnology, Inc.

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