XBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemXBP-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38627
Gene NameX-box binding protein 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameX-box binding protein 1
NCBI Gene AliasesTREB-5, TREB5, XBP-1, XBP2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Endoplasmic reticulum stress enhances the expression of TLR3-induced TSLP by airway epitheliumAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyMay 1, 2024Prabuddha S. Pathinayake, Alan C.-Y. Hsu, Kristy S. Nichol, Jay C. Horvat, Philip M. Hansbro, Peter A. B. WarkBECs. Gene knockdown. Small interfering (si)RNAs were used for gene silencing. XBP1-silencer siRNA (200 nM, sc-38627; Santa Cruz Biotechnology), CHOP-stealth RNAi siRNA (100 nM, VHS40605; Life Technologies, Australia),

(2) NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma Tumor GrowthMolecular Cancer ResearchApril 2, 2024Chufan Cai, Jiayi Tu, Jeronimo Najarro, Rukang Zhang, Hao Fan, Freya Q. Zhang, Jiacheng Li, Zhicheng Xie, Rui Su, Lei Dong, et al.FlexiTube siRNA (Qiagen, SI03019345).Hs_ATF6_5 FlexiTube siRNA (Qiagen, SI03019205).XBP-1 siRNA (h): sc-38627 (SANTA CRUZ BIOTECHNOLOGY).Control siRNA (Qiagen, 1022076). Construction of shRNA knockdown plasmids All

(3) The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cellsBiochemical and biophysical research communicationsJuly 12, 2022Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M.

(4) TXNIP Links Anticipatory Unfolded Protein Response to Estrogen Reprogramming Glucose Metabolism in Breast Cancer CellsEndocrinologyJanuary 1, 2022Wang Y, Chen S.

(5) IRE1α-XBP1 but not PERK inhibition exerts anti-tumor activity in osteosarcomaDiscov OncolNovember 30, 2021Sasa K, Saito T, Kurihara T, Hasegawa N, Sano K, Kubota D, Akaike K, Okubo T, Hayashi T, Takagi T, et al.(143B, MG63, KHOS, and U2OS). XBP1 siRNA knockdown was also performed using pre-designed XBP1 siRNA (sc-38627: Santa Cruz or siRNA negative control, Sigma-Aldrich), EIF2A siRNA (s38344, s38345: Silencer™ Select Pre-Designed siRNA

(6) Endoplasmic reticulum stress/XBP1 promotes airway mucin secretion under the influence of neutrophil elastaseInternational journal of molecular medicineMay 1, 2021Xu X, Li Q, Li L, Zeng M, Zhou X, Cheng Z.

(7) PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune FunctionMolecular cancer therapeuticsMay 1, 2021Gilardini Montani MS, Benedetti R, Piconese S, Pulcinelli FM, Timperio AM, Romeo MA, Masuelli L, Mattei M, Bei R, D'Orazi G, et al.

(8) IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 ActivationBiomedicinesJanuary 27, 2021Gonnella R, Gilardini Montani MS, Guttieri L, Romeo MA, Santarelli R, Cirone M.according to the manufacturer’s instructions (Santa Cruz Biotechnology, Inc., Heidelberg, Germany, sc38627). Briefly, 3 × 105 cells were seeded in six-well culture plates in RPMI medium without antibiotics for

(9) A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repair via an unfolded protein responseFASEB journal : official publication of the Federation of American Societies for Experimental BiologyDecember 1, 2019Royal JM, Oh YJ, Grey MJ, Lencer WI, Ronquillo N, Galandiuk S, Matoba N.

(10) Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelial-mesenchymal transition and invasion in breast cancer cellsCell death & diseaseApril 24, 2019Zhang N, Zhu T, Yu K, Shi M, Wang X, Wang L, Huang T, Li W, Liu Y, Zhang J.siRNA (sc-40780), GFAT siRNA (sc-6068), CEBPB siRNA (sc-29862), CHOP siRNA (sc-156118), XBP1 siRNA (sc-38627) and scrambled siRNA (sc-37007) were obtained from Santa Cruz Biotechnology (CA, USA). Transfection

(11) Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosisScientific reportsJanuary 24, 2019Han R, Hu S, Qin W, Shi J, Zeng C, Bao H, Liu Z.siRNA (sc-35290), ERα siRNA (sc-29305), GR siRNA (sc-35505), snail siRNA(sc-38398) and XBP-1s siRNA (sc-38627) were bought from Santa Cruz (Dallas, Texas, USA). LOC105375913 siRNA was bought from Thermo fisher

(12) IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signalingNature communicationsJanuary 24, 2019Sheng X, Nenseth HZ, Qu S, Kuzu OF, Frahnow T, Simon L, Greene S, Zeng Q, Fazli L, Rennie PS, et al.and were negative of mycoplasma contamination. Reagents XBP1 siRNA was purchased from Santa Cruz (sc-38627), Allstar Negative Control siRNA was from Qiagen (SI03650318), the human pCDNA3-Flag-XBP1s expression

(13) The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosisThe Journal of biological chemistryDecember 28, 2018Hu S, Han R, Shi J, Zhu X, Qin W, Zeng C, Bao H, Liu Z.

(14) Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 CellsChinese medical journalOctober 5, 2018Yu X, Ren LP, Wang C, Zhu YJ, Xing HY, Zhao J, Song GY.

(15) O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistanceCell death & diseaseMay 1, 2018Liu Y, Cao Y, Pan X, Shi M, Wu Q, Huang T, Jiang H, Li W, Zhang J.following the manufacturer’s instructions. OGT siRNA (sc-40780), GFAT siRNA (sc-6068), XBP1 siRNA (sc-38627), GRP78 siRNA (sc-29338) and scrambled siRNA (sc-37007) were obtained from Santa Cruz Biotechnology

(16) IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcomaOncotargetMarch 6, 2018Tanabe Y, Suehara Y, Kohsaka S, Hayashi T, Akaike K, Mukaihara K, Kurihara T, Kim Y, Okubo T, Ishii M, et al.(Thermo Fisher Scientific). XBP1 siRNA knockdown was also performed using pre-designed XBP1 siRNA (sc-38627, Santa Cruz; or siRNA negative control, Sigma-Aldrich). After 72 h, the total protein and RNA from each

(17) Regulation of Nrf2 by X Box-Binding Protein 1 in Retinal Pigment EpitheliumFrontiers in geneticsJanuary 1, 2018Chen C, Zhong Y, Wang JJ, Yu Q, Plafker K, Plafker S, Zhang SX.

(18) 3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cellsOncotargetAugust 29, 2017Go DH, Lee YG, Lee DH, Kim JA, Jo IH, Han YS, Jo YH, Kim KY, Seo YK, Moon JH, et al.

(19) Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 elementScientific reportsFebruary 13, 2017Déry MA, LeBlanc AC.pools of three siRNAs targeting PrP (sc-36318), Luman (sc-37702), murine Luman (sc-37703) or XBP1 (sc-38627) were purchase from Santa Cruz Biotechnologies (Dallas, TX). Silencing of Luman in primary human neurons

(20) Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 ModulationThe Journal of infectious diseasesJanuary 15, 2017Tang AC, Saferali A, He G, Sandford AJ, Strug LJ, Turvey SE.

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XBP-1 siRNA (h)

XBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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XBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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