TSG-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTSG-6 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-39819
Gene Nametumor necrosis factor, alpha-induced protein 6
Quantity10 µM
Specieshuman
NCBI Full Gene NameTNF alpha induced protein 6
NCBI Gene AliasesTSG-6, TSG6
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) TSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cellsScientific reportsAugust 22, 2025Lim GH, An JH, Lee JH, Seo KW, Youn HY.specific siRNA (si-TSG6) or scrambled siRNA (si-ctrl) (Santa Cruz Biotechnology, Dallas, TX, USA; Cat# sc-39819 and sc-37007, respectively) for 48 h using Lipofectamine RNAiMAX (Invitrogen; Cat# 56532), according

(2) Tumour necrosis factor stimulated gene 6 intrinsically regulates PD-L1 expressions in breast cancer cells, leading to modulation of tumour microenvironmentVeterinary and comparative oncologyJune 1, 2023Lee JH, An JH, Youn HY.

(3) Antifibrotic TSG-6 Expression Is Synergistically Increased in Both Cells during Coculture of Mesenchymal Stem Cells and Macrophages via the JAK/STAT Signaling PathwayInternational journal of molecular sciencesOctober 28, 2022Gong SC, Yoon Y, Jung PY, Kim MY, Baik SK, Ryu H, Eom YW.

(4) TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling PathwayContrast media & molecular imagingJanuary 1, 2022Cui H, Zhang L, Chen B, Zhang F, Xu H, Ma G, Cao L, Wang M.

(5) Human Umbilical Cord Mesenchymal Stem Cells-Secreted TSG-6 Is Anti-Inflammatory and Promote Tissue Repair After Spinal Cord InjuryASN NeuroMay 17, 2021Ziling Liao, Wei Wang, Weiyue Deng, Yuying Zhang, Aishi Song, Sihao Deng, Huifang Zhao, Shusheng Zhang, Zhiyuan Li70%-90%, hucMSCs were transfected with 20 nM siRNA against human TSG-6 (Santa Cruz Biotechnology Cat# sc-39819, USA) or NC siRNA (Santa Cruz Biotechnology Cat# sc-37007, USA). While transfecting, we diluted TSG-6

(6) Enhanced expression of cyclooxygenase-2 related multi-drug resistance gene in melanoma and osteosarcoma cell lines by TSG-6 secreted from canine adipose-derived mesenchymal stem/stromal cellsVeterinary medicine and scienceMay 1, 2021Yang SJ, An JH, Park SM, Lee JH, Chae HK, Lee KM, Song WJ, Youn HY.LMeC cell lines were transfected with siCOX‐2 (sc‐29279), while cADSCs were transfected with siTSG‐6 (sc‐39819). The control group was transfected with control siRNA (sc‐37007). Lipofectamine 2000 (Invitrogen)‐siRNA

(7) Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue HomeostasisCell reportsMarch 17, 2020Ko JH, Kim HJ, Jeong HJ, Lee HJ, Oh JY.

(8) TSG-6 in extracellular vesicles from canine mesenchymal stem/stromal is a major factor in relieving DSS-induced colitisPloS oneJanuary 1, 2020An JH, Li Q, Ryu MO, Nam AR, Bhang DH, Jung YC, Song WJ, Youn HY.reached approximately 70% confluence, they were transfected for 48 h with TSG-6 siRNA or control siRNA (sc-39819 and sc-27007, respectively, Santa Cruz Biotechnology, Dallas, TX, USA) using Lipofectamine RNAiMAX (Invitrogen,

(9) Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal FibrosisStem cells translational medicineDecember 1, 2018Yoshida K, Nakashima A, Doi S, Ueno T, Okubo T, Kawano KI, Kanawa M, Kato Y, Higashi Y, Masaki T.flow cytometry. Transfection with TSG‐6 siRNA SF‐hMSCs were transfected with 20 nM siRNA against human TSG‐6 (sc‐39819; Santa Cruz Biotechnology, Santa Cruz, CA) or NC siRNA (sc‐37007; Santa Cruz Biotechnology) using Lipofectamine 2000 Transfection Reagent

(10) TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in miceStem cell research & therapySeptember 26, 2018Li Q, Song WJ, Ryu MO, Nam A, An JH, Ahn JO, Bhang DH, Jung YC, Youn HY.

(11) Kynurenic acid, an IDO metabolite, controls TSG-6-mediated immunosuppression of human mesenchymal stem cellsCell death and differentiationJuly 1, 2018Wang G, Cao K, Liu K, Xue Y, Roberts AI, Li F, Han Y, Rabson AB, Wang Y, Shi Y.

(12) Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6Stem cell research & therapyJune 26, 2018Chaubey S, Thueson S, Ponnalagu D, Alam MA, Gheorghe CP, Aghai Z, Singh H, Bhandari V.

(13) TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in miceStem cell research & therapyApril 6, 2018Song WJ, Li Q, Ryu MO, Ahn JO, Bhang DH, Jung YC, Youn HY.

(14) Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent MannerMolecular therapy : the journal of the American Society of Gene TherapyJanuary 3, 2018Song HB, Park SY, Ko JH, Park JW, Yoon CH, Kim DH, Kim JH, Kim MK, Lee RH, Prockop DJ, et al.

(15) Human Amniotic Membrane Mesenchymal Stem Cells inhibit Neutrophil Extracellular Traps through TSG-6Scientific reportsSeptember 29, 2017Magaña-Guerrero FS, Domínguez-López A, Martínez-Aboytes P, Buentello-Volante B, Garfias Y.Opti-MEM and Lipofectamine 2000. The siRNA of tsg-6 and the scrambled control siRNA (Santa Cruz, TX, USA; sc-39819; sc-37007, respectively) were diluted with Opti-MEM at a concentration of 20 pM, according to the manufacturer’s

(16) TSG-6 Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells Ameliorates DSS-induced colitis by Inducing M2 Macrophage Polarization in MiceScientific reportsJuly 12, 2017Song WJ, Li Q, Ryu MO, Ahn JO, Ha Bhang D, Chan Jung Y, Youn HY.they reach approximately 40% confluence, hAT-MSCs were transfected with TSG-6 siRNA or control siRNA (sc-39819 and sc-37007, respectively; Santa Cruz Biotechnology, Santa Cruz, CA, USA) for 48 h using Lipofectamine

(17) Comparison of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in a murine model of corneal injuryCytotherapyJanuary 1, 2017Yun YI, Park SY, Lee HJ, Ko JH, Kim MK, Wee WR, Reger RL, Gregory CA, Choi H, Fulcher SF, et al.

(18) Corneal stromal stem cells reduce corneal scarring by mediating neutrophil infiltration after woundingPloS oneJanuary 1, 2017Hertsenberg AJ, Shojaati G, Funderburgh ML, Mann MM, Du Y, Funderburgh JL.grown overnight in a 100 mm culture dish were transfected with TSG-6 siRNA (Santa Cruz Biotechnologies, sc-39819) or a scrambled control siRNA (sc-3007), 42 nM in 9 ml SGM medium using Viromer Blue transfection agent

(19) Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritisCell death & diseaseDecember 22, 2016Shin TH, Kim HS, Kang TW, Lee BC, Lee HY, Kim YJ, Shin JH, Seo Y, Won Choi S, Lee S, et al.

(20) Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6Scientific reportsDecember 5, 2016He Z, Hua J, Qian D, Gong J, Lin S, Xu C, Wei G, Meng H, Yang T, Zhou B, et al.1 day, after which they were used as the target cells for transfection with 20 nM siRNA for TSG-6 (sc-39819; Santa Cruz Biotechnology, Santa Cruz, CA, USA) or scrambled siRNA (sc-37007; Santa Cruz Biotechnology)

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TSG-6 siRNA (h)

TSG-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TSG-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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