Smurf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSmurf2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41675
Gene NameSMAD specific E3 ubiquitin protein ligase 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameSMAD specific E3 ubiquitin protein ligase 2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) SMURF1/2 are novel regulators of WNK1 stabilitybioRxivSeptember 21, 2024Ankita B. Jaykumar, Sakina Plumber, Derk Binns, Chonlarat Wichaidit, Katherine Luby-Phelps, Melanie H. Cobb4390844) as in [99], OSR1 siRNA (Thermo Fisher Scientific, s19303 Silencer® Select), and SMURF2 siRNA (sc-41675, Santa Cruz Biotechnology). HDMEC cells were transfected with 20 nM siRNA using Lipofectamine RNAiMax

(2) SMURF1/2 Are Novel Regulators of WNK1 StabilityKinases and PhosphatasesSeptember 20, 2024Ankita B. Jaykumar, Sakina Plumber, Derk Binns, Chonlarat Wichaidit, Katherine Luby-Phelps, Melanie H. Cobb4390844) as in [9], OSR1 siRNA (Thermo Fisher Scientific, USA; s19303 Silencer® Select), and SMURF2 siRNA (sc-41675, Santa Cruz Biotechnology, USA) were used. HDMEC cells were transfected with 20 nM siRNA using Lipofectamine

(3) DNA topoisomerase II inhibition potentiates osimertinib’s therapeutic efficacy in EGFR-mutant non–small cell lung cancer modelsJournal of Clinical InvestigationMay 15, 2024Zhen Chen, Karin A. Vallega, Dongsheng Wang, Zihan Quan, Songqing Fan, Qiming Wang, Ticiana Leal, Suresh S. Ramalingam, Shi-Yong SunGene knockdown using siRNA and shRNA. TOP2A siRNA (sc-36695), TOP2A shRNA plasmid (sc-36695-SH), SMURF2 siRNA (sc-41675), and SMURF2 shRNA plasmid (sc-41675-SH) were purchased from Santa Cruz Biotechnology. Scrambled control,

(4) SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cellsCell death & diseaseSeptember 30, 2023Yang S, Yang G, Wang X, Xiang J, Kang L, Liang Z.siRNA Ctrl (Cat. No. sc-37007, Santa Cruz), siRNA SIRT2 (sc-40988, Santa Cruz), siRNA SMURF2 (Cat. No. sc-41675, Santa Cruz), and siRNA P/CAF (Cat. No. sc-36198, Santa Cruz) were transfected using Lipofectamine 3000

(5) The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosisJournal of biomedical scienceJanuary 7, 2023Jeon S, Jin H, Kim JM, Hur Y, Song EJ, Lee YJ, Na Y, Cho J, Lee YS.p3xflag-myc-HSP27S15D/S78D/S82D were prepared and pCMV5B-Flag-Smurf2-WT was from Addgene (plasmid #11746). siRNAs against Smurf2 (sc-41675) and a control siRNA (sc-37007) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). For

(6) Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligaseOncotargetSeptember 28, 2021Zhao S, El-Deiry WS.

(7) Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patientsBurns : journal of the International Society for Burn InjuriesSeptember 1, 2021Zhang Z, Liu C, Chen B, Tang W, Liu Z, Cao W, Li X.

(8) The HECT ubiquitin E3 ligase Smurf2 degrades μ-opioid receptor 1 in the ubiquitin-proteasome system in lung epithelial cellsAmerican journal of physiology. Cell physiologyMay 1, 2019Dong S, Liu J, Li L, Wang H, Ma H, Zhao Y, Zhao J.

(9) Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progressionBMC cancerMarch 13, 2018David D, Surendran A, Thulaseedharan JV, Nair AS.

(10) Role of tumor necrosis factor-α in epithelial-to-mesenchymal transition in transplanted kidney cells in recipients with chronic allograft dysfunctionGeneFebruary 5, 2018Zhao C, Xu Z, Wang Z, Suo C, Tao J, Han Z, Gu M, Tan R.

(11) Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2Cancer researchJune 1, 2016Kim DG, Lee JY, Lee JH, Cho HY, Kang BS, Jang SY, Kim MH, Guo M, Han JM, Kim SJ, et al.

(12) KRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated β-TrCP1 degradationNeoplasia (New York, N.Y.)February 1, 2014Shukla S, Allam US, Ahsan A, Chen G, Krishnamurthy PM, Marsh K, Rumschlag M, Shankar S, Whitehead C, Schipper M, et al.

(13) Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent mannerCell divisionJanuary 1, 2014David D, Jagadeeshan S, Hariharan R, Nair AS, Pillai RM.

(14) Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradationJournal of the American Society of Nephrology : JASNOctober 1, 2006Tan R, Zhang J, Tan X, Zhang X, Yang J, Liu Y.control. For siRNA inhibition studies, HKC were transfected with control siRNA (sc-37007) or Smurf2 siRNA (sc-41675; Santa Cruz Biotechnology) at the final concentration of 120 nM by using oligofectamine reagent according

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Smurf2 siRNA (h)

Smurf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Smurf2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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