YAP siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemYAP siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38637
Quantity10 µM
TypesiRNA/dsRNA
NCBI Gene AliasesCOB1, YAP, YAP-1, YAP2, YAP65, YKI
NCBI Full Gene NameYes1 associated transcriptional regulator
Specieshuman
Gene NameYes-associated protein 1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Fluid shear stress enhances pancreatic cancer motility through YAP activationClinical EpigeneticsMay 20, 2026Juan Deng, Giulia Lencioni, Aldo Pastore, Adam E. Frampton, Dongmei Deng, Elisa Giovannettiwith YAP-targeting siRNA Cells were transfected with YAP-targeting siRNA (Santa Cruz Biotechnology, sc-38637) or control siRNA (Thermo Fisher Scientific) using a lipid-based transfection reagent according to the

(2) Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial ActivityTheranosticsMay 18, 2026Yingbo Guo, Siyong Peng, Thibaud Jamet, Virginie Firlej, Marie Irondelle, Constance Nau, Christophe A. Girard, Kaushal Asrani, Tamara L. Lotan, Romain Huc, et al.5’-CCU-ACA-UCC-CGA-UCG-AUG-AUG-TT-3’. siYAP1 #1 (ID:107951) from ThermoFisher Scientific (France), or the siYAP1 #2 (sc38637) Santa-Cruz Biotechnology (Germany). Cell viability was systematically assessed by nuclear morphology

(3) Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate CancerInternational Journal of Biological SciencesJanuary 1, 2026Ágata Sofia Assunção Carreira, Marianna Ciuffreda, Nathakan Thongon, Charles M. Haughey, Adam Pickard, Sharon L. Eddie, Rebecca E. Steele, Elena Cerri, Romina Belli, Daniele Peroni, et al.YAP5SA Transient transfection of siSCR (Santa Cruz Biotechnology, sc-37007), siYAP (Santa Cruz Biotechnology, sc-38637), and siNNMT (Santa Cruz Biotechnology, sc-61213), as well as for the pQCXIH-Myc- empty or pQCXIH-Myc

(4) Activation of the Hippo Pathway by ATN Suppresses Cancer Stem-Like Properties and EGFR-Associated Signaling in Castration-Resistant Prostate Cancer Cells in vitroInternational journal of medical sciencesJanuary 1, 2026Lin KJ, Liu JM, Lin HW, Weng JR, Dokla EME, Lu MT, Chu PC.Discovery, Cat#D-001206-13-05) and YAP siRNA was purchased from Santa Cruz Biotechnology (Santa Cruz, Cat#sc-38637). The plasmid or siRNA was introduced into cells using Lipofectamine 2000 (Thermo Fisher Scientific,

(5) Pulsatile low shear stress increases susceptibility to endothelial inflammation via upregulation of IFT and activation of YAPAPL BioengJune 11, 2025Yu Hou, Hazel R. C. Screen, Martin M. Knightaccording to the manufacturer's protocols. For YAP disruption, cells were transfected with 10 μM YAP siRNA (sc-38637, Santa Cruz Biotechnology). For IFT/primary cilia disruption, cells were transfected with 10 μM IFT88

(6) UFMylation maintains YAP stability to promote vascular endothelial cell senescenceiScienceFebruary 21, 2025Yanan Liu, Min Zuo, Aiwei Wu, Zhaoxiang Wang, Siting Wang, Yongping Bai, Junzhi Zhou, Hu WangLaboratories,N/A ,, Oligonucleotides,Oligonucleotides,Oligonucleotides ,, Primer sequences,Table S1,N/A YAP1 siRNA,Santa Cruz Biotechnology,Cat# sc-38637 UFM1 siRNA,Santa Cruz Biotechnology,Cat# sc-76804 UFL1 siRNA,Santa Cruz Biotechnology,Cat# sc-95134 Negative

(7) Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targetsJournal of Clinical InvestigationDecember 1, 2023Ricardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Spyros Karaiskos, Eleanor M. Plaster, Claudia Loebel, Gizem Efe, Tatiana Karakasheva, Joel T. Gabre, Jianhua Hu, et al.of the experiment. For in vitro experiments using siRNA, YAP siRNA (Santa Cruz Biotechnology Inc., sc-38637) or control (scrambled) siRNA (MilliporeSigma, SIC003) was introduced into the cells using the Lipofectamine RNAiMAX Transfection Reagent

(8) Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targetsJ Clin InvestDecember 1, 2023Ricardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Spyros Karaiskos, Eleanor M. Plaster, Claudia Loebel, Gizem Efe, Tatiana Karakasheva, Joel T. Gabre, Jianhua Hu, et al.of the experiment. For in vitro experiments using siRNA, YAP siRNA (Santa Cruz Biotechnology Inc., sc-38637) or control (scrambled) siRNA (MilliporeSigma, SIC003) was introduced into the cells using the Lipofectamine RNAiMAX Transfection Reagent

(9) Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in ConfinementAdvanced science (Weinheim, Baden-Wurttemberg, Germany)August 1, 2023Hemmati F, Akinpelu A, Song J, Amiri F, McDaniel A, McMurray C, Afthinos A, Andreadis ST, Aitken AV, Biancardi VC, et al.corresponding vehicle controls. For gene knockdown experiments, cells were transfected with YAP1 siRNA (sc‐38637; Santa Cruz Biotechnology), P53 siRNA (sc‐29435; Santa Cruz Biotechnology), LATS2 siRNA (sc‐37444; Santa Cruz Biotechnology

(10) YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1BiomoleculesJune 6, 2023Patrícia Barros, Ana M. Matos, Paulo Matos, Peter JordanEurofins Genomics was used as a mock control, and the siRNAs used to deplete YES1 (sc-29860), YAP1 (sc-38637) or SHC1 (sc-29480) were commercial mixes (each composed of three different oligonucleotides) from Santa Cruz Biotechnology

(11) COL1A1 expression induced by overexpression of both a 15‑amino acid peptide from the fibrinogen domain of tenascin‑X and integrin α11 in LX‑2 cellsMolecular medicine reportsNovember 1, 2022Matsumoto KI, Kawakami K, Yamada K, Takeshita H.plates in DMEM with 2% FBS. Then the medium was changed to DMEM with 0.5% FBS. Fifty nM YAP1 siRNA (sc-38637; Santa Cruz Biotechnology, Inc.), which is a pool of 3 target-specific siRNAs (sc-38637A, sc-38637B,

(12) Salt-inducible kinase 1 deficiency promotes vascular remodeling in pulmonary arterial hypertension via enhancement of yes-associated protein-mediated proliferationHeliyonOctober 1, 2022Pu J, Wang F, Ye P, Jiang X, Zhou W, Gu Y, Chen S.and a relative scrambled siRNA were designed and synthesized by GenePharma (China). Human YAP siRNA (sc-38637) was purchased from Santa Cruz Biotechnology. SIK1 adenovirus (Ad SIK1) and null adenovirus (Ad null)

(13) A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and AngiogenesisCancer Res CommunJuly 12, 2022Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, Jaya Padmanabhan, Domenico Coppola, Srikumar ChellappanRNA-mediated Depletion Assays The two different siRNAs for YAP1 were purchased from Santa Cruz Biotechnology (sc-38637) and Thermo Fisher Scientific (107951), respectively. siRNAs For TAZ (sc-45232), MST1 (sc-39249), MST2

(14) A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and AngiogenesisCancer Res CommunJuly 1, 2022Bora-Singhal N, Saha B, Mohankumar D, Padmanabhan J, Coppola D, Chellappan S.RNA-mediated Depletion Assays The two different siRNAs for YAP1 were purchased from Santa Cruz Biotechnology (sc-38637) and Thermo Fisher Scientific (107951), respectively. siRNAs For TAZ (sc-45232), MST1 (sc-39249), MST2

(15) ETV4 potentiates nuclear YAP retention and activities to enhance the progression of hepatocellular carcinomaCancer lettersJuly 1, 2022Xu X, Wang B, Liu Y, Jing T, Xu G, Zhang L, Kun Jiao, Chen Z, Xiang L, Xu C, et al.

(16) Endoplasmic Reticulum Stress Contributed to Dipyridamole-Induced Impaired Autophagic Flux and Glioma ApoptosisInternational journal of molecular sciencesJanuary 6, 2022Chang CY, Wu CC, Wang JD, Liao SL, Chen WY, Kuan YH, Wang WY, Chen CJ.

(17) Disrupting biological sensors of force promotes tissue regeneration in large organismsNature communicationsSeptember 6, 2021Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, et al.control (scrambled) siRNA (Santa Cruz Biotechnology, sc-37007), YAP1 siRNA (Santa Cruz Biotechnology, sc-38637), or EGR1 siRNA (Santa Cruz Biotechnology, sc-29303). Cells were incubated with this siRNA transfection reagent

(18) Chimeric RNA-binding protein-based killing switch targeting hepatocellular carcinoma cellsMolecular therapy. Nucleic acidsSeptember 3, 2021Yang J, Ding S.min, 450 nm, 5.8 mV/cm2. siRNAs for gene knockdown siRNAs used to knockdown AFP (sc-88864), YAP1 (sc-38637), LATS1 (sc-35797), and MOB1B (sc270319) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA).

(19) YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathwaysOncogenesisMay 4, 2021Ou WB, Lundberg MZ, Zhu S, Bahri N, Kyriazoglou A, Xu L, Chen T, Mariño-Enriquez A, Fletcher JA.Life Technologies), RAF1 siRNA (5′-AAUAGUUCAGCAGUUUGGCUA-3′, Invitrogen Life Technologies), YAP siRNA (sc-38637), TAZ siRNA (sc-38568, Santa Cruz Biotechnology), YWHAE-NUTM2-FLAG, or YWHAE-HA constructs were incubated

(20) Low-Temperature Argon Plasma Regulates Skin Moisturizing and Melanogenesis-Regulating Markers through Yes-Associated ProteinInternational journal of molecular sciencesFebruary 14, 2021Kim HY, Agrahari G, Lee MJ, Tak LJ, Ham WK, Kim TY.

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YAP siRNA (h)

YAP siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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YAP siRNA (h) from Santa Cruz Biotechnology, Inc.

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