TopBP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTopBP1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41068
Gene Nametopoisomerase (DNA) II binding protein 1
Quantity10 µM
Specieshuman
NCBI Full Gene NameDNA topoisomerase II binding protein 1
NCBI Gene AliasesDpb11, TOP2BP1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repairElifeApril 14, 2025Artem K Velichko, Nadezhda V Petrova, Dmitry A Deriglazov, Anastasia P Kovina, Artem V Luzhin, Eugene P Kazakov, Igor I Kireev, Sergey V Razin, Omar L Kantidzesequences of the siRNA is provided in Supplementary file 3) or 50 nM TOPBP1 (Santa Cruz Biotechnology, #sc-41068). For CRISPR/Cas9-mediated knockout, two sgRNA to first exon of the TCOF1 gene were designed using the

(2) Treacle and TOPBP1 control replication stress response in the nucleolusThe Journal of cell biologyAugust 2, 2021Velichko AK, Ovsyannikova N, Petrova NV, Luzhin AV, Vorobjeva M, Gavrikov AS, Mishin AS, Kireev II, Razin SV, Kantidze OL.Santa Cruz Biotechnology), 50 nM Treacle/TCOF1 (#sc-61707; Santa Cruz Biotechnology), 50 nM TOPBP1 (#sc-41068; Santa Cruz Biotechnology), and 50 nM ETAA1 (#sc-94927; Santa Cruz Biotechnology). The TOPBP1 knockout

(3) Calcein-acetoxymethy ester enhances the antitumor effects of doxorubicin in nonsmall cell lung cancer by regulating the TopBP1/p53RR pathwayAnti-cancer drugsSeptember 1, 2017Lv Y, Liu R, Xie S, Zheng X, Mao J, Cai Y, Chen W.

(4) Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 SignalingCell reportsFebruary 21, 2017Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, Zuo X, Song JH, Maity SN, Manyam GC, et al.from Qiagen, ARsi1 (s1538) and ARsi2 (s1540) were purchased from Life Technologies, and TOPBP1si_sc (sc-41068) was purchased from Santa Cruz. Gene knockdown experiments were performed using the Lipofectamine RNAiMax transfection reagent

(5) TopBP1 contributes to the chemoresistance in non-small cell lung cancer through upregulation of p53Drug design, development and therapyJanuary 1, 2016Lv Y, Huo Y, Yu X, Liu R, Zhang S, Zheng X, Zhang X.

(6) Human MutY homolog induces apoptosis in etoposide-treated HEK293 cellsOncology lettersDecember 1, 2012Hahm SH, Chung JH, Agustina L, Han SH, Yoon IS, Park JH, Kang LW, Park JW, Na JJ, Han YS.described (14). ATR siRNA (sc‑29763) and TopBP1 siRNA were purchased from Santa Cruz Biotechnology, Inc. (sc‑41068; Santa Cruz, CA, USA). ATR and TopBP1 knockdown were conducted according to the manufacturer's instructions. Protein extraction

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TopBP1 siRNA (h)

TopBP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TopBP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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