α-synuclein siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemα-synuclein siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29619
Gene Namesynuclein, alpha (non A4 component of amyloid precursor)
Quantity10 µM
Specieshuman
NCBI Full Gene Namesynuclein alpha
NCBI Gene AliasesNACP, PARK1, PARK4, PD1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) α-Synuclein modulates fibronectin expression in the trabecular meshwork independent of TGFβ2Experimental eye researchJanuary 1, 2023Adulla A, Patel U, Ashok A, Katiyar P, Kaulakis M, Kritikos AE, Pillai S, Lee H, Lindner E, Rhee DJ, et al.No: 13778075). Dexamethasone (D1756) was obtained from Sigma Aldrich, USA. siRNA stocks for α-Syn (sc 29619) and scrambled sequences (sc37007) were obtained from Santa Cruz Biotechnology, USA. Monomeric human

(2) Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane compositionCell reportsAugust 23, 2022Mahoney-Sanchez L, Bouchaoui H, Boussaad I, Jonneaux A, Timmerman K, Berdeaux O, Ayton S, Krüger R, Duce JA, Devos D, et al.

(3) Death-associated Protein Kinase 1 Phosphorylates α-Synuclein at Ser129 and Exacerbates Rotenone-induced Toxic Aggregation of α-Synuclein in Dopaminergic SH-SY5Y CellsExperimental neurobiologyJune 30, 2020Shin WH, Chung KC.(SNCA)-speciﬁc small interfering RNAs (siRNAs) were designed and synthesized by Santa Cruz Biotechnology (sc-29619). Cell culture and preparation of cell lysates Mouse embryonic ﬁbroblasts (MEFs) derived from DAPK1-KO

(4) α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's diseaseScientific reportsOctober 9, 2017Baksi S, Singh N.Technologies, USA). Stable cell lines expressing vector or α-syn were used for the studies. α-Syn siRNA (sc-29619) and control siRNA (sc-37007) were procured from Santa Cruz Biotechnology Inc., USA. RPE47 cells were

(5) α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca²⁺ homeostasis and mitochondrial ATP productionActa neuropathologicaJuly 1, 2017Paillusson S, Gomez-Suaga P, Stoica R, Little D, Gissen P, Devine MJ, Noble W, Hanger DP, Miller CCJ.described [43, 78]. Control and human α-synuclein siRNAs were from Santa Cruz Biotechnology (sc-37007 and sc-29619, respectively). Antibodies Rabbit and rat antibodies to VAPB and PTPIP51 were as described [20]. Mouse

(6) Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cellsOncotargetJune 27, 2017Vo MT, Choi SH, Lee JH, Hong CH, Kim JS, Lee UH, Chung HM, Lee BJ, Park JW, Cho WJ.transfection reagent (R0531, Thermo Scientific). Small interfering RNAs (siRNAs) against human α-Syn (α-Syn-siRNA, sc-29619), human TTP (TTP-siRNA, sc-36760) and control siRNA (scRNA, sc-37007) were purchased from Santa Cruz Biotechnology, Inc

(7) Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's diseaseFree radical biology & medicineAugust 1, 2016Baksi S, Tripathi AK, Singh N.A53T–EGFP was purchased from Addgene (#40823). RNAi knockdown Author Manuscript siRNA against α-syn (sc-29619) and control siRNA (sc-37007) were purchased from Santa Cruz Biotechnology Inc, USA. RPE47 cells were

(8) Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug ScreeningPloS oneJanuary 1, 2015Dansithong W, Paul S, Scoles DR, Pulst SM, Huynh DP.siRNAs; Control siRNA (Santa Cruz Inc.; cat# sc-37007) and α-synuclein siRNA (Santa Cruz Inc.; cat# sc-29619) at a concentration of 100 nM were transfected into GFP12 or Luc6B cells using lipofectamine 2000 (Invitrogen

(9) α-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's diseaseJournal of neurochemistryDecember 1, 2014Bir A, Sen O, Anand S, Khemka VK, Banerjee P, Cappai R, Sahoo A, Chakrabarti S.

(10) Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathwayFrontiers in aging neuroscienceJanuary 1, 2014Jiang P, Gan M, Lin WL, Yen SH.

(11) Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brainThe Journal of biological chemistryApril 4, 2008Devi L, Raghavendran V, Prabhu BM, Avadhani NG, Anandatheerthavarada HK.

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