Smad3 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSmad3 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38376
TypesiRNA/dsRNA
NCBI Gene AliasesHSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, mad3
NCBI Full Gene NameSMAD family member 3
Specieshuman
Quantity10 µM
Gene NameMAD homolog 3 (Drosophila)

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) TGF-β1/SMAD signaling downregulates KLF4 expression via direct transcriptional suppression and FAT10-mediated proteasomal degradation in hepatocellular carcinomaCell & BioscienceJanuary 6, 2026Zeping Chen, Senlin Zhao, Desheng Chen, Yichao Lou, Hanhao Lu, Qihang Yao, Jie Lu, Hongcheng Sunduplexes are listed in Supplementary Table S1. Verified SMAD2 siRNA (sc-38374, Santa Cruz), SMAD3 siRNA (sc-38376, Santa Cruz), and SMAD2/3 siRNA (sc-37238, Santa Cruz) duplexes were used to knock down the target gene. Transient transfection

(2) TGFβ1 signaling protects chondrocytes against oxidative stress via FOXO1-autophagy axisOsteoarthritis and cartilageNovember 1, 2021Kurakazu I, Akasaki Y, Tsushima H, Sueishi T, Toya M, Kuwahara M, Uchida T, Lotz MK, Nakashima Y.

(3) High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathwayBiology openMay 15, 2021Guo W, Gao H, Pan W, Yu P, Che G.

(4) The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasisOncogeneJune 1, 2020Huang WJ, Tian XP, Bi SX, Zhang SR, He TS, Song LY, Yun JP, Zhou ZG, Yu RM, Li M.China). The sequence of shLINC01278 and siTCF-4 is shown in Table S3. siSmad2 (sc-38374), siSmad3 (sc-38376), and siβ-catenin (sc-29209), were purchased from Santa Cruz. The sequence of miR-1258-mut and LINC01278-mut

(5) Dual role of RACK1 in airway epithelial mesenchymal transition and apoptosisJournal of cellular and molecular medicineMarch 1, 2020Pu Y, Liu YQ, Zhou Y, Qi YF, Liao SP, Miao SK, Zhou LM, Wan LH.chemically synthesized, double‐stranded RACK1 siRNA (h, sc‐36354), double‐stranded Smad3 siRNA (h, sc‐38376) and negative control siRNA (NC, sc‐37007) were purchased from Santa Cruz. Double‐stranded JNK siRNA

(6) IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membraneAmerican journal of physiology. Renal physiologyFebruary 1, 2020Yang X, Yan H, Jiang N, Yu Z, Yuan J, Ni Z, Fang W.

(7) Recombinant Pyrin Domain Protein Attenuates Airway Inflammation and Alleviates Epithelial-Mesenchymal Transition by Inhibiting Crosstalk Between TGFβ1 and Notch1 Signaling in Chronic Asthmatic MiceFrontiers in physiologyJanuary 1, 2020Wang Z, Li L, Wang C, Piao Y, Jiang J, Li L, Yan G, Piao H.of Smad3 expression, cells were co-transfected with 1.5 μM of Smad3 siRNA (Santa Cruz Biotechnology, SC-38376) or negative control siRNA (Santa Cruz Biotechnology, sc-37007) for 48 h. The transfection efficiency

(8) Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasionBiology openJune 28, 2019Hu Q, Myers M, Fang W, Yao M, Brummer G, Hawj J, Smart C, Berkland C, Cheng N.h. 8 pmol of siRNAs to control (Ambion, cat. no. AM4613), SMAD3 (Santa Cruz Biotechnology, cat. no. sc-38376), p42MAPK (Santa Cruz Biotechnology cat. no. sc-29307) mixed with p44MAPK (Santa Cruz Biotechnology,

(9) C3a and suPAR drive versican V1 expression in tubular cells of focal segmental glomerulosclerosisJCI insightApril 4, 2019Han R, Hu S, Qin W, Shi J, Hou Q, Wang X, Xu X, Zhang M, Zeng C, Liu Z, et al.

(10) SMAD3 silencing enhances DNA damage in radiation therapy by interacting with MRE11-RAD50-NBS1 complex in gliomaJournal of biochemistryApril 1, 2019Jiang Z, Guo Y, Miao L, Han L, Zhang W, Jiang Y.

(11) MDM2 promotes epithelial-mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinomaOncoTargets and therapyJanuary 1, 2019Tang Y, Xuan Y, Qiao G, Ou Z, He Z, Zhu Q, Liao M, Yin G.

(12) TGFβ and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cellsThe Journal of biological chemistryMay 25, 2018Leiphrakpam PD, Brattain MG, Black JD, Wang J.

(13) Deregulation of Hippo-TAZ pathway during renal injury confers a fibrotic maladaptive phenotypeFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2018Anorga S, Overstreet JM, Falke LL, Tang J, Goldschmeding RG, Higgins PJ, Samarakoon R.

(14) Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δEBioMedicineMay 1, 2018Zhou T, Luo M, Cai W, Zhou S, Feng D, Xu C, Wang H.

(15) Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cellsCancer lettersFebruary 28, 2018Rahn S, Zimmermann V, Viol F, Knaack H, Stemmer K, Peters L, Lenk L, Ungefroren H, Saur D, Schäfer H, et al.

(16) Correction: Opposing Effects of PI3K/Akt and Smad-Dependent Signaling Pathways in NAG-1-Induced Glioblastoma Cell ApoptosisPloS oneJanuary 1, 2018Zhang Z, Wu L, Wang J, Li G, Feng D, Zhang B, Li L, Yang J, Ma L, Qin H.siRNA, Smad3 siRNA, and control siRNA products purchased from Santa Cruz Biotechnogy are sc-38374, sc-38376 and sc-44231, respectively. • The adenovirus infection protocol used in the study was as follows: Cells

(17) TGFβ3 recruits endogenous mesenchymal stem cells to initiate bone regenerationStem cell research & therapyNovember 10, 2017Deng M, Mei T, Hou T, Luo K, Luo F, Yang A, Yu B, Pang H, Dong S, Xu J.

(18) Frizzled-7 mediates TGF-β-induced pulmonary fibrosis by transmitting non-canonical Wnt signalingExperimental cell researchOctober 1, 2017Guan S, Zhou J.

(19) HSP27 regulates TGF-β mediated lung fibroblast differentiation through the Smad3 and ERK pathwaysInternational journal of molecular medicineJanuary 1, 2017Wang G, Jiao H, Zheng JN, Sun X.

(20) TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in CancerCancer discoveryDecember 1, 2016Park BV, Freeman ZT, Ghasemzadeh A, Chattergoon MA, Rutebemberwa A, Steigner J, Winter ME, Huynh TV, Sebald SM, Lee SJ, et al.1.5 μM of siRNA for Smad2 (Santa Cruz Biotechnology, SC-38374) and Smad3 (Santa Cruz Biotechnology, SC-38376). Cytokine and Drug Treatments Human recombinant IL-1α, IL-2, IL-4, IL-6, IL-10, IL-12, IL-13, IL-15,

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Smad3 siRNA (h)

Smad3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Smad3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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