PXR siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPXR siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44057
Gene Namenuclear receptor subfamily 1, group I, member 2
Quantity10 µM
Specieshuman
NCBI Full Gene Namenuclear receptor subfamily 1 group I member 2
NCBI Gene AliasesBXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
TypesiRNA/dsRNA

Add to Compare List

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Autophagy and PXR Crosstalk in the Regulation of Cancer Drug Metabolism and Resistance According to Gene Mutational Status in Colorectal CancerGenes (Basel)July 28, 2025Evangelos Koustas, Panagiotis Sarantis, Eleni-Myrto Trifylli, Eleftheria Dikoglou-Tzanetatou, Evangelia Ioakeimidou, Ioanna A. Anastasiou, Michalis V. Karamouzis, Stamatios Theocharisbands. 2.5. siRNA and Transfection For the siRNA transfection experiments, we used siRNA to knock down PXR (sc-44057, Santa Cruz Biochemicals, Santa Cruz, CA, USA) and Lipofectamine 3000 (#L3000-15 Invitrogen Corp.).

(2) PXR activation impairs hepatic glucose metabolism partly via inhibiting the HNF4α-GLUT2 pathwayActa pharmaceutica Sinica. BMay 1, 2022Liu P, Jiang L, Kong W, Xie Q, Li P, Liu X, Zhang J, Liu M, Wang Z, Zhu L, et al.

(3) A microbial metabolite remodels the gut-liver axis following bariatric surgeryCell host & microbeMarch 10, 2021Chaudhari SN, Luo JN, Harris DA, Aliakbarian H, Yao L, Paik D, Subramaniam R, Adhikari AA, Vernon AH, Kiliç A, et al.siRNA,Santa Cruz Biotechnology,Cat. No. sc-106692 Human PXR siRNA,Santa Cruz Biotechnology,Cat. No. sc-44057 Human FXR siRNA,Santa Cruz Biotechnology,Cat. No. sc-38848 Human CAR siRNA,Santa Cruz Biotechnology,Cat.

(4) Xiaoaiping injection enhances paclitaxel efficacy in ovarian cancer via pregnane X receptor and its downstream moleculesJournal of ethnopharmacologyOctober 28, 2020Zhang XQ, Ding YW, Chen JJ, Xiao X, Zhang W, Zhou L, Kong QW, Shi MZ, Yang J, Jiang B, et al.

(5) PXR-ABC drug transporters/CYP-mediated ursolic acid transport and metabolism in vitro and vivoArchiv der PharmazieSeptember 1, 2020Jinhua W, Ying Z, Yuhua L.

(6) Z-guggulsterone regulates MDR1 expression mainly through the pregnane X receptor-dependent manner in human brain microvessel endothelial cellsEuropean journal of pharmacologyMay 5, 2020Xu HB, Tang ZQ, Wang J, Kong PS.

(7) Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel DiseaseFrontiers in pharmacologyJanuary 1, 2020Yu Z, Yue B, Ding L, Luo X, Ren Y, Zhang J, Mani S, Wang Z, Dou W.ligands. Gene Silencing 1×106 LS174T cells were electroporated with the hPXR small-interfering RNA (siRNA) (sc-44057, Santa Cruz Biotech., CA) or the control siRNA using Lonza Nucleofector II instrument (Amaxa Biosystems,

(8) Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathwayScientific reportsNovember 12, 2019Ren Y, Yue B, Ren G, Yu Z, Luo X, Sun A, Zhang J, Han M, Wang Z, Dou W.(ATCC). For the hPXR knockdown assay, 1 × 106 LS174T cells were electroporated with the hPXR siRNA (sc-44057, Santa Cruz Biotech., CA) or the control siRNA using Lonza Nucleofector II instrument (Amaxa Biosystems,

(9) Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by RifampicinMolecular pharmacologyAugust 1, 2017Yan L, Wang Y, Liu J, Nie Y, Zhong XB, Kan Q, Zhang L.

(10) Recent applications of the combination of mesoporous silica nanoparticles with nucleic acids: development of bioresponsive devices, carriers and sensorsBiomaterials scienceFebruary 28, 2017Castillo RR, Baeza A, Vallet-Regí M.

(11) Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cellsInternational journal of oncologySeptember 1, 2016Masuyama H, Nakamura K, Nobumoto E, Hiramatsu Y.

(12) The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2)Toxicology and applied pharmacologyAugust 1, 2016Rigalli JP, Perdomo VG, Ciriaci N, Francés DE, Ronco MT, Bataille AM, Ghanem CI, Ruiz ML, Manautou JE, Catania VA.transfected by incubation for 48 h with PXR siRNA (h) (Santa Cruz Biotechnology, Santa Cruz, CA, USA; sc-44057, PXR− cells) or a non-targeting siRNA (Santa Cruz Biotechnology, sc-37007, PXR+ cells), as a control.

(13) Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicityPloS oneJanuary 1, 2015Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.later. Human PXR was transiently knocked down with 100 nM of PXR siRNA (h) (Santa Cruz Biotechnology, sc-44057) targeting the human PXR mRNA (PXRcells). Control siRNA-A (Santa Cruz Biotechnology, sc-37007), a non-targeting

(14) Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathwayThe Journal of nutritional biochemistrySeptember 1, 2014Dou W, Zhang J, Li H, Kortagere S, Sun K, Ding L, Ren G, Wang Z, Mani S.protease inhibitor cocktail tablets were from Roche Diagnostics, Mannheim, Germany. PXR siRNA duplex (sc-44057) and control siRNA duplex (sc-37007) were from Santa Cruz Biotechnology, CA. Horseradish peroxidase-conjugated

(15) Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathwayThe Journal of pharmacology and experimental therapeuticsJune 1, 2013Dou W, Zhang J, Zhang E, Sun A, Ding L, Chou G, Wang Z, Mani S.et al., 2012). PXR Silencing. A total of 1 106 HepG2 cells were electroporated with PXR siRNA (h) (sc-44057; Santa Cruz Biotechnology) targeting the human PXR mRNA. Control siRNA (sc-37007; Santa Cruz Biotechnology),

(16) Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptorPLoS neglected tropical diseasesJanuary 1, 2012Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.transfection 24 h later. Human PXR was transiently knock down with PXR siRNA (h) (Santa Cruz Biotechnology, sc-44057) targeting the human nuclear receptor mRNA. Control siRNA-A (Santa Cruz Biotechnology, sc-37007), a

(17) Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cellsToxicologyJuly 11, 2011Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

(18) Activated protein C enhances human keratinocyte barrier integrity via sequential activation of epidermal growth factor receptor and Tie2The Journal of biological chemistryFebruary 25, 2011Xue M, Chow SO, Dervish S, Chan YK, Julovi SM, Jackson CJ.

Be the First to Write a Review!

PXR siRNA (h)

PXR siRNA (h) from Santa Cruz Biotechnology, Inc.

Description

Santa Cruz Biotechnology, Inc.

Citations (18)

Reviews

PXR siRNA (h) from Santa Cruz Biotechnology, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map