Smad2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSmad2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38374
Gene NameSMAD family member 2
Quantity10 µM
Specieshuman
NCBI Full Gene NameSMAD family member 2
NCBI Gene AliasesCHTD8, JV18, JV18-1, LDS6, MADH2, MADR2, hMAD-2, hSMAD2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) TGF-β1/SMAD signaling downregulates KLF4 expression via direct transcriptional suppression and FAT10-mediated proteasomal degradation in hepatocellular carcinomaCell & BioscienceJanuary 6, 2026Zeping Chen, Senlin Zhao, Desheng Chen, Yichao Lou, Hanhao Lu, Qihang Yao, Jie Lu, Hongcheng Sunspecific sequences of the siRNA duplexes are listed in Supplementary Table S1. Verified SMAD2 siRNA (sc-38374, Santa Cruz), SMAD3 siRNA (sc-38376, Santa Cruz), and SMAD2/3 siRNA (sc-37238, Santa Cruz) duplexes

(2) TGFβ1 signaling protects chondrocytes against oxidative stress via FOXO1-autophagy axisOsteoarthritis and cartilageNovember 1, 2021Kurakazu I, Akasaki Y, Tsushima H, Sueishi T, Toya M, Kuwahara M, Uchida T, Lotz MK, Nakashima Y.

(3) Fluid flow exposure promotes epithelial-to-mesenchymal transition and adhesion of breast cancer cells to endothelial cellsBreast cancer research : BCROctober 12, 2021Fuh KF, Shepherd RD, Withell JS, Kooistra BK, Rinker KD.

(4) PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancerJournal for immunotherapy of cancerAugust 1, 2020Shen Y, Teng Y, Lv Y, Zhao Y, Qiu Y, Chen W, Wang L, Wang Y, Mao F, Cheng P, et al.

(5) The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasisOncogeneJune 1, 2020Huang WJ, Tian XP, Bi SX, Zhang SR, He TS, Song LY, Yun JP, Zhou ZG, Yu RM, Li M.Biotechnology Co (Guangzhou, China). The sequence of shLINC01278 and siTCF-4 is shown in Table S3. siSmad2 (sc-38374), siSmad3 (sc-38376), and siβ-catenin (sc-29209), were purchased from Santa Cruz. The sequence of miR-1258-mut

(6) MicroRNA-31/184 is involved in transforming growth factor-β-induced apoptosis in A549 human alveolar adenocarcinoma cellsLife sciencesFebruary 1, 2020Wang CJ, Li BB, Tan YJ, Zhang GM, Cheng GL, Ren YS.

(7) MDM2 promotes epithelial-mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinomaOncoTargets and therapyJanuary 1, 2019Tang Y, Xuan Y, Qiao G, Ou Z, He Z, Zhu Q, Liao M, Yin G.

(8) Stemness and chemoresistance are imparted to the OC cells through TGFβ1 driven EMTJournal of cellular biochemistryJuly 1, 2018Mitra T, Prasad P, Mukherjee P, Chaudhuri SR, Chatterji U, Roy SS.

(9) TGFβ and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cellsThe Journal of biological chemistryMay 25, 2018Leiphrakpam PD, Brattain MG, Black JD, Wang J.

(10) MicroRNA-26a inhibits hyperplastic scar formation by targeting Smad2Experimental and therapeutic medicineMay 1, 2018Qi J, Liu Y, Hu K, Zhang Y, Wu Y, Zhang X.

(11) Rapamycin activates TGF receptor independently of its ligand: implications for endothelial dysfunctionClinical science (London, England : 1979)February 28, 2018Miyakawa AA, Girão-Silva T, Krieger JE, Edelman ER.

(12) Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cellsCancer lettersFebruary 28, 2018Rahn S, Zimmermann V, Viol F, Knaack H, Stemmer K, Peters L, Lenk L, Ungefroren H, Saur D, Schäfer H, et al.

(13) Correction: Opposing Effects of PI3K/Akt and Smad-Dependent Signaling Pathways in NAG-1-Induced Glioblastoma Cell ApoptosisPloS oneJanuary 1, 2018Zhang Z, Wu L, Wang J, Li G, Feng D, Zhang B, Li L, Yang J, Ma L, Qin H.the Smad2 siRNA, Smad3 siRNA, and control siRNA products purchased from Santa Cruz Biotechnogy are sc-38374, sc-38376 and sc-44231, respectively. • The adenovirus infection protocol used in the study was as follows:

(14) Connexin43 Controls the Myofibroblastic Differentiation of Bronchial Fibroblasts from Patients with AsthmaAmerican journal of respiratory cell and molecular biologyJuly 1, 2017Paw M, Borek I, Wnuk D, Ryszawy D, Piwowarczyk K, Kmiotek K, Wójcik-Pszczoła KA, Pierzchalska M, Madeja Z, Sanak M, et al.

(15) TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in CancerCancer discoveryDecember 1, 2016Park BV, Freeman ZT, Ghasemzadeh A, Chattergoon MA, Rutebemberwa A, Steigner J, Winter ME, Huynh TV, Sebald SM, Lee SJ, et al.knock-down, the cells were co-transfected with 1.5 μM of siRNA for Smad2 (Santa Cruz Biotechnology, SC-38374) and Smad3 (Santa Cruz Biotechnology, SC-38376). Cytokine and Drug Treatments Human recombinant IL-1α,

(16) Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκkB-PUMA SignalingMedical science monitor : international medical journal of experimental and clinical researchJune 30, 2016Yin Q, Liu S, Dong A, Mi X, Hao F, Zhang K.

(17) Kisspeptin 10 inhibits the Warburg effect in breast cancer through the Smad signaling pathway: both in vitro and in vivoAmerican journal of translational researchJanuary 1, 2016Song GQ, Zhao Y.

(18) SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer MetastasisCancer researchApril 1, 2015Yu L, Liu X, Cui K, Di Y, Xin L, Sun X, Zhang W, Yang X, Wei M, Yao Z, et al.

(19) The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditionsMedical oncology (Northwood, London, England)January 1, 2015Shen X, Xue Y, Si Y, Wang Q, Wang Z, Yuan J, Zhang X.

(20) Nuclear SMAD2 restrains proliferation of glioblastomaCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2015Yu Y, Ran Q.

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Smad2 siRNA (h)

Smad2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Smad2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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