PGC-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPGC-1α siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38884
Quantity10 µM
Specieshuman
NCBI Full Gene NamePPARG coactivator 1 alpha
NCBI Gene AliasesLEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1
TypesiRNA/dsRNA
Gene Nameperoxisome proliferator-activated receptor gamma, coactivator 1 alpha

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosisCell death & diseaseSeptember 26, 2022Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ.from Sigma (St Louis, MO, USA). Control siRNA (sc-37007), Nrf2 siRNA (sc-37030), and PGC-1α siRNA (sc-38884) were purchased from Santa Cruz (Santa Cruz, CA, USA). Click-iT Plus terminal deoxynucleotidyl transferase

(2) Chlorogenic acid alleviated liver fibrosis in methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice and its mechanismThe Journal of nutritional biochemistryAugust 1, 2022Miao H, Ouyang H, Guo Q, Wei M, Lu B, Kai G, Ji L.

(3) SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1Cellular & molecular immunologyAugust 1, 2022Zhang S, Wang J, Wang L, Aliyari S, Cheng G.24 h. siRNA-mediated gene knockdown The pooled siRNAs against human SIRT1 (sc-40986) and PGC-1α (sc-38884) were purchased from Santa Cruz Biotechnology. For siRNA transfection. siRNA against target genes were

(4) Ginsenoside Rg3 Attenuates TNF-α-Induced Damage in Chondrocytes through Regulating SIRT1-Mediated Anti-Apoptotic and Anti-Inflammatory MechanismsAntioxidants (Basel, Switzerland)December 10, 2021Ma CH, Chou WC, Wu CH, Jou IM, Tu YK, Hsieh PL, Tsai KL.

(5) Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPKα-PGC-1α-ERRα Circuit after Traumatic Brain InjuryInternational journal of molecular sciencesDecember 3, 2021Kim M, Kim J, Moon S, Choi BY, Kim S, Jeon HS, Suh SW, Kim YM, Choi YK.

(6) Dexmedetomidine Exerts Renal Protective Effect by Regulating the PGC-1α/STAT1/IRF-1 AxisNephronJanuary 1, 2021Song YC, Liu R, Li RH, Xu F.

(7) N-Acetyl Cysteine Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Intracellular Triglyceride Accumulation by Preserving Mitochondrial FunctionFrontiers in pharmacologyJanuary 1, 2021Hang W, Shu H, Wen Z, Liu J, Jin Z, Shi Z, Chen C, Wang DW.NAD+/NADH was then calculated. siRNA Transfection Homo sapiens PGC1a siRNA was purchased from Santa Cruz (sc-38884). 4 ul siRNA was transfected by 4 ul Lipo 2000 (Invitrogen) to 1 well of 6-well cell culture plate.

(8) Nuclear respiratory factor 1 (NRF-1) upregulates the expression and function of reduced folate carrier (RFC) at the blood-brain barrierFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2020Alam C, Hoque MT, Sangha V, Bendayan R.

(9) Silent Mating-Type Information Regulation 2 Homolog 1 Attenuates the Neurotoxicity Associated with Alzheimer Disease via a Mechanism Which May Involve Regulation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-αThe American journal of pathologyJuly 1, 2020Dong YT, Cao K, Xiang J, Shan L, Guan ZZ.

(10) HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma modelsThe Journal of clinical investigationJuly 1, 2020Nguyen TTT, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela A, Humala N, Mahajan A, et al.

(11) The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cellsScientific reportsAugust 14, 2019Jacoupy M, Hamon-Keromen E, Ordureau A, Erpapazoglou Z, Coge F, Corvol JC, Nosjean O, Mannoury la Cour C, Millan MJ, Boutin JA, et al.(SI05217905)-specific siRNA (Qiagen), MPPB (L-004747-00-0005)-specific siRNA (Dharmacon), PGC-1-α siRNA (sc38884, Santa Cruz), RNAi negative control (12935-200), PINK1 (HSS127945) and Parkin (HSS107593)-specific stealth

(12) Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of MitofusinCell metabolismApril 2, 2019Wu MJ, Chen YS, Kim MR, Chang CC, Gampala S, Zhang Y, Wang Y, Chang CY, Yang JY, Chang CJ.

(13) Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse modelsAgingFebruary 13, 2019Chen CM, Chen WL, Hung CT, Lin TH, Lee MC, Chen IC, Lin CH, Chao CY, Wu YR, Chang KH, et al.expression of specific genes in TBP/Q79-GFP SH-SY5Y cells, small interfering RNA (siRNA) targeting PGC-1α (sc-38884), NRF2 (sc-37030), NFYA (sc-29947) and a scrambled control (sc-37007) (Santa Cruz Biotechnology) were

(14) Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 SignalingAntioxidants & redox signalingJanuary 10, 2019Zeng X, Yang J, Hu O, Huang J, Ran L, Chen M, Zhang Y, Zhou X, Zhu J, Zhang Q, et al.

(15) PGC1α downregulation and glycolytic phenotype in thyroid cancerJournal of CancerJanuary 1, 2019Liu CL, Yang PS, Wang TY, Huang SY, Kuo YH, Cheng SP.

(16) Pyruvate Protects against Cellular Senescence through the Control of Mitochondrial and Lysosomal Function in Dermal FibroblastsThe Journal of investigative dermatologyDecember 1, 2018Kim JY, Lee SH, Bae IH, Shin DW, Min D, Ham M, Kim KH, Lee TR, Kim HJ, Son ED, et al.

(17) Antagonizing CD105 enhances radiation sensitivity in prostate cancerOncogeneAugust 1, 2018Madhav A, Andres A, Duong F, Mishra R, Haldar S, Liu Z, Angara B, Gottlieb R, Zumsteg ZS, Bhowmick NA.siRNAs by transfecting with either control siRNA-A (sc-37007, Santa Cruz Biotechnology), PGC-1α siRNA (sc-38884, Santa Cruz Biotechnology) or P53 siRNA (sc-29435, Santa Cruz Biotechnology). Cells were transfected

(18) Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemiaRedox biologyApril 1, 2018Chen T, Dai SH, Li X, Luo P, Zhu J, Wang YH, Fei Z, Jiang XF.and transfection The specific siRNA targeted Sirt1 (Si-Sirt1, sc-40986), Sirt3 (Si-Sirt3, sc-61555), PGC1 (Si-PGC1, sc-38884) and control siRNA (Si-Control, sc-37007), which should not knock down any known proteins, were purchased

(19) Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuitPloS oneJanuary 1, 2018Choi YK, Park JH, Yun JA, Cha JH, Kim Y, Won MH, Kim KW, Ha KS, Kwon YG, Kim YM.

(20) Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathwayFree radical biology & medicineNovember 1, 2017Song C, Zhao J, Fu B, Li D, Mao T, Peng W, Wu H, Zhang Y.

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PGC-1α siRNA (h)

PGC-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PGC-1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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