PDK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPDK1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36203
Quantity10 µM
Specieshuman
NCBI Full Gene Namepyruvate dehydrogenase kinase 1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer modelsChemico-biological interactionsJune 1, 2023Guo Y, Zhou Y, Wu P, Ran M, Xu N, Shan W, Sha O, Tam KY.

(2) The oncogenic and prognostic role of PDK1 in the progression and metastasis of ovarian cancerJournal of CancerJanuary 1, 2021Yao S, Shang W, Huang L, Xu R, Wu M, Wang F.

(3) PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signalingOncogenesisFebruary 18, 2020Siu MKY, Jiang YX, Wang JJ, Leung THY, Ngu SF, Cheung ANY, Ngan HYS, Chan KKL.stable silencing of PDK1 and DCA treatment For transient silencing, siRNA specifically targeting PDK1 (sc-36203) and control siRNA (Santa Cruz Biotechnology, Inc., Santa Cruz, CA) were introduced into SKOV-3 and

(4) Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8(+) T cell function and survival through elevation of PD-L1OncoimmunologyJanuary 1, 2019Wang JJ, Siu MK, Jiang YX, Leung TH, Chan DW, Cheng RR, Cheung AN, Ngan HY, Chan KK.

(5) The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancerCancer & metabolismJanuary 1, 2019Zhuang Y, Ly RC, Frazier CV, Yu J, Qin S, Fan XY, Goetz MP, Boughey JC, Weinshilboum R, Wang L.signaling, cat# 3700), Cleaved PARP (Cell signaling, Cat#5625), ubiquitin (Abcam, ab7780), PDK1 (Santa Cruz,sc36203), PDK2 (Santa Cruz, sc517284), SNAP-Tag (New England Biolab, p9310s), mCherry (Sigma, SAB2702291), Peroxidase-AffiniPure

(6) Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical SciencesOctober 15, 2018Zhang SL, Yang Z, Hu X, Chakravarty H, Tam KY.

(7) Prostaglandin E2 stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesisRespiratory researchDecember 18, 2015Fan Y, Wang Y, Wang K.

(8) Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signalingCellular signallingDecember 1, 2015Moon G, Kim J, Min Y, Wi SM, Shim JH, Chun E, Lee KY.

(9) COL11A1 confers chemoresistance on ovarian cancer cells through the activation of Akt/c/EBPβ pathway and PDK1 stabilizationOncotargetSeptember 15, 2015Wu YH, Chang TH, Huang YF, Chen CC, Chou CY.

(10) miR-138 inhibits proliferation by targeting 3-phosphoinositide-dependent protein kinase-1 in non-small cell lung cancer cellsThe clinical respiratory journalJanuary 1, 2015Ye XW, Yu H, Jin YK, Jing XT, Xu M, Wan ZF, Zhang XY.

(11) An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer modelsBreast cancer research : BCRJanuary 1, 2013Xia W, Petricoin EF 3rd, Zhao S, Liu L, Osada T, Cheng Q, Wulfkuhle JD, Gwin WR, Yang X, Gallagher RI, et al.

(12) PKC-ι promotes glioblastoma cell survival by phosphorylating and inhibiting BAD through a phosphatidylinositol 3-kinase pathwayBiochimica et biophysica actaJune 1, 2011Desai S, Pillai P, Win-Piazza H, Acevedo-Duncan M.

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PDK1 siRNA (h)

PDK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PDK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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